CAS: 109-75-1; 3-Butenenitrile

该化合物是一种有机化合物,其特点是不饱和的硝三烯结构,其特点是四碳链,第二和第三碳原子之间有双重联系,以及碳终端中含有一个环状体.该化合物一般是无色的,可粉黄,具有独特的气味,在乙醇和乙醇等有机溶剂中溶解,但水溶性有限.3-丁烯三烯因其再活动性而闻名,特别是在聚合反应方面,使其在合成各种聚合物和共聚物方面有用.此外,它可以经受典型的变异作用,例如添加反应,并可用于生产特殊化学品.由于它具有潜在的毒性和易燃性,在处理该物质时应当采取适当的安全措施.其应用范围遍及各个行业,包括塑料,树脂和其他化学中间体的生产.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号106-95-6 烯丙基溴 | CAS号75-86-5 丙酮氰醇 | CAS号5314-34-1 2-Butenal, oxime | CAS号7319-38-2 but-3-enal | CAS号593-60-2 溴乙烯 | CAS号75-05-8 乙腈 | CAS号65300-07-4 triphenyl(P,P,P... | CAS号151-50-8 氰化钾 | CAS号143-33-9 氰化钠 | CAS号2835-21-4 Allyl is°Cyanide | CAS号1067-99-8 4-(diethoxymeth... | CAS号3724-55-8 3-丁烯酸甲酯 | CAS号3524-33-2 1-乙基-3-甲基-1H-吡唑-5-胺 | CAS号461-98-3 4-氨基-2,6-二甲基嘧啶 | CAS号541-35-5 丁酰胺 | CAS号64-17-5 乙醇 | CAS号79-39-0 甲基丙烯酰胺 | CAS号44565-27-7 4-氨基-2-甲基-1-丁醇 | CAS号3724-65-0 巴豆酸 | CAS号300-85-6 DL-3-羟基丁酸

合成工艺路线路线简述

  • 合成目标产物 3-Butenenitrile 主要起始原料 Sodium:Cyanide And Allyl Chloride
  • (文献来源)合成步骤主要原料 Sodium:Cyanide 和 Allyl Chloride
天然芥菜籽油置于铜,Paraffin Oil体系中,化学反应生成烯丙基腈
参考文献:De259364
标题:De259364

海关参考信息

专利信息


专利号:WO-2023102600-A1
优先权日:2021-12-06
标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
权利人:NEWSOUTH INNOVATIONS PTY LTD
摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

专利号:EP-0020401-B1
优先权日:1978-09-21
标 题 :Improved process for the synthesis of 1,4-diaza-2-cycloalkanone and substituted derivatives thereof
摘要:Improved process for the synthesis of 1,4-diaza-2-cycloalkanones and substituted derivatives thereof involving solid-liquid phase transfer phenomenon. More specifically, the subject compounds are prepared by combining a substituted diamine and suitable coreactant in the presence of a phase transfer catalyst and caustic.

专利号:US-RE46218-E
优先权日:2011-01-05
标 题 :Process for the synthesis of agomelatine
发明人:ZARD SAMIR; SIRE BÉATRICE; BOUMEDIENE MEHDI
权利人:SERVIER LAB
摘要:Process for the industrial synthesis of the compound of formula (I)

专利号:US-8835661-B2
优先权日:2011-08-26
标 题:Process for the synthesis of C11 and C12 omega-aminoalkanoic acid esters comprising a nitrilation step
发明人:COUTURIER JEAN-LUC; DUBOIS JEAN-LUC
权利人:COUTURIER JEAN-LUC; DUBOIS JEAN-LUC; ARKEMA FRANCE
摘要:A process for the synthesis of C11 and C12 ω-amino-alkanoic acid esters including a step of continuous nitrilation in the gas phase or in a mixed gas-liquid phase, a step of metathesis and a step of reduction by hydrogenation, using, as raw material, C10 and C11 ω-alkenoic acid esters.

专利号:US-8748651-B2
优先权日:2008-11-17
标题:Method for the synthesis of an omega-amino acid or ester starting from a monounsaturated fatty acid or ester
发明人:DUBOIS JEAN-LUC
权利人:DUBOIS JEAN-LUC; ARKEMA FRANCE
摘要:The invention relates to a method for the synthesis of ω-amino alkanoic acids or esters thereof starting from unsaturated natural fatty acids passing through an ω-unsaturated nitrile intermediate compound.

专利号:US-2004203036-A1
优先权日:2001-07-09
标 题 :Multimer polynucleotide synthesis
发明人:STENGELE KLAUS-PETER; PFLEIDERER WOLFGANG
摘要:The present invention relates to a process for the preparation of polynucleotides, whereby under suitable usual conditions the free 5′-hydroxy group, whose terminal 3′-hydroxy group contains a usual protecting group, is reacted with a hydroxy group, derivatized in a previous reaction step to a phosphite amidoester, phosphpotriester or phosphonic acid ester, whereby said hydroxy group is a 3′-hydroxy function of a free or solid phase bound polynucleotide, or a solid phase bound hydroxy function. n Further the present invention relates to a kit for performing a process according to the invention, which contains at least one or more selected oligonucleotides, having a free 5′-hydroxy group and a protected 3′-hydroxy group. Further on, the present invention relates to new oligonucleotides and their use as building blocks for the synthesis of polynucleotides in the process according to the invention. n Furthermore the present invention relates to the use of the process according to the invention or the use of the kits for the preparation of poly/oligonucleotides resp. polynucleotide libraries or nucleic acid chips.
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主要参考文献

参考标题:An Alternative Synthesis Of The Non-Small Cell Lung Carcinoma Drug Afatinib
作者:Tatjana Kovacevic,Milan Mesic,Amir Avdagic,Miroslav Zegarac |发布日期:2018.11
摘要:Afatinib (Bibw2992) Is The Anticancer Drug Developed By Boehringer Ingelheim. This Work Is Reporting The Synthesis Of The Afatinib Using A New Route By Ullmann-Goldberg Reaction From Corresponding 4-Anilinoquinazoline Iodide As The Last Step In The Synthesis. This Route Was Not Described Previously And It Could Be Used For Synthesis Of Afatinib Analogues.

合成参考文献


摘要:Michalak, M.; Gulajski, L.; Grela, K., Science of Synthesis, (2010) 47, 333.
摘要:Michalak, M.; Gulajski, L.; Grela, K., Science of Synthesis, (2010) 47, 340.
摘要:Clark, R. W.; Wiskur, S. L., Science of Synthesis Knowledge Updates, (2015) 1, 16.
摘要:Molander, G. A.; Beaumard, F., Science of Synthesis Knowledge Updates, (2013) 3, 122.
摘要:Okamoto, K.; Ohe, K., Science of Synthesis Knowledge Updates, (2020) 1, 113.
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