CAS: 112811-66-2; 2,4,5-Trifluoro-3-Methoxybenzoyl Chloride

相似化合物

870837-66-4 881190-46-1 112811-65-1

上下游产品

CAS号112811-65-1 2,4,5-三氟-3-甲氧基苯甲酸 | CAS号136897-64-8 2,4,5-三氟-3-甲氧基苯甲酸甲酯 | CAS号112811-71-9 1-环丙基-6,7-二氟-1,... | CAS号112811-68-4 3-氧代-3(2,4,5-三氟... | CAS号351368-41-7 3-氨基-1-环丙基-6,7-... | CAS号351367-87-8 1-cyclopropyl-6... | CAS号112811-67-3 (E)-ethyl 3-eth... | CAS号112811-64-0 3-METHOXY-2,4,5... | CAS号865246-09-9 2-(2,4,5-TRIFLU... | CAS号865246-27-1 2,4,5-三氟-N-(1-羟... | CAS号922491-07-4 9-cyclopropyl-6... | CAS号922718-28-3 7-bromo-9-cyclo...

N-甲基四氟酞酰亚胺置于氯化亚砜,Sodium Hydroxide体系中,化学反应 25.0H,反应生成2,4,5-三氟-3-甲氧基苯甲酰氯
参考文献:一种加替沙星环合酯的合成方法
标题:一种加替沙星环合酯的合成方法
摘要:本发明属于药物中间体的生产工艺,具体公开了一种加替沙星环合酯的合成方法,合成方法以3,4,5,6‑四氟‑n‑甲基邻苯二甲酰亚胺为起始原料,经过水解,脱羧,甲基化得到2,4,5‑三氟‑3‑甲氧基苯甲酰氯,2,4,5‑三氟‑3‑甲氧基苯甲酰氯先与n,N‑二甲氨基丙烯酸乙酯偶联,再与环丙胺置换,最后在dmf和氟化钾的作用下环合生成加替沙星环合酯;反应的合成路线短,原料来源更易,且反应条件温和,易操作控制,降低了原料消耗,后处理方便,降低了成本;反应使用氟化钾代替碳酸钾,不仅能够减少废气的产生,且使用后的氟化钾可以通过氢氧化钾调节后继续使用,进一步降低了成本.

专利信息

专利号:US-11530178-B2
优先权日:2018-01-18
标题 :Hyper-branched compounds, synthesis and uses thereof
发明人：ANTONY PRINCE JAMES SELVARAJ
权利人:MEMSIFT INNOVATIONS PTE LTD
摘要:The present invention relates to hyper-branched compounds, a method of synthesizing the hyper-branched compounds and applications of the hyper-branched compounds. The hyper-branched compounds of the present invention include hyper-branched fluorinated compounds, hyper-branched fluorinated graphene and hyper-branched amine functionalized graphene oxide.

专利号:US-8946422-B2
优先权日:2005-07-27
标题:8-methoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones and related compounds as anti-infective agents
发明人：BRADBURY BARTON JAMES; WILES JASON ALLAN; WANG QIUPING; HASHIMOTO AKHIRO; LUCIEN EDLAINE; PAIS GODWIN CLARENCE GILROY; DESHPANDE MILIND; PUCCI MICHEAL JOHN; KIM HA YOUNG
权利人:BRADBURY BARTON JAMES; WILES JASON ALLAN; WANG QIUPING; HASHIMOTO AKHIRO; LUCIEN EDLAINE; PAIS GODWIN CLARENCE GILROY; DESHPANDE MILIND; PUCCI MICHEAL JOHN; KIM HA YOUNG; ACHILLION PHARMACEUTICALS INC
摘要:The invention provides compound and salts of Formula I and II, disclosed herein, which includes compounds of Formula A and Formula B: Such compounds possess useful antimicrobial activity. The variables R2, R3, R5, R6, R7, and R9 shown in Formula A and B are defined herein. Certain compounds of Formula I and Formula II disclosed herein are potent and/or selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula I or Formula II and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula I or Formula II as the only active agent or may contain a combination of a compound of Formula I or Formula II and one or more other active agents. The invention also provides methods for treating microbial infections in animals.

专利号:CN-120136785-A
优先权日:2023-12-13
标题:Synthesis method of 1-cyclopropyl-6, 7-difluoro-1, 4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid n-propyl ester