CAS: 27012-25-5; 5-Bromo-2-Phenylpyridine

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CAS号223463-13-6 5-溴-2-碘吡啶 | CAS号98-80-6 苯硼酸 | CAS号624-28-2 2,5-二溴吡啶 | CAS号591-50-4 碘苯 | CAS号56673-34-8 5-溴-2-巯基吡啶 | CAS号100-58-3 苯基溴化镁 | CAS号143-66-8 四苯硼钠 | CAS号108-86-1 溴苯 | CAS号626-55-1 3-溴吡啶 | CAS号591-18-4 1-溴-3-碘苯 | CAS号1008-89-5 2-苯基吡啶 | CAS号15827-72-2 2,5-二苯基吡啶 | CAS号155079-10-0 2-苯基吡啶-5-硼酸

4-溴-2-碘吡啶置于tris-(Dibenzylideneacetone)Dipalladium(0),Silver Tetrafluoroborate,异丙基氯化镁体系中,用 四氢呋喃,N,N-二甲基甲酰胺 用作溶剂,化学反应 19.0H,反应生成5-溴-2-苯基吡啶
参考文献:有机锗烷的正交纳米颗粒催化.
标题:有机锗烷的正交纳米颗粒催化.
摘要:尽管纳米颗粒被广泛用作催化剂,但与均相分子或本体非均相催化剂相比,其潜在的引发特权转化的能力知之甚少.我们在本文中证明(并合理化)纳米颗粒在芳基卤化物与芳基锗烷的交叉偶联中显示出与分子催化剂正交的反应性.芳基锗烷在ln Pd0 / Ln Pdii催化中不反应并允许已存在的偶合体选择性官能化,但它们在pd纳米颗粒条件下显示出优异的反应活性,超过了已建立的偶合体(如arbpin和arbmida),并且具有耐空气性,无碱基且正交获得有价值且具挑战性的联芳基图案.与众所周知的不稳定的多氟芳基和2-吡啶基硼酸相反,相应的德语非常稳定并且易于耦合.我们的机理和计算研究为纳米颗粒催化提供了明确的支持,并表明由于芳基锗烷的电子丰富,它们优先通过亲电子芳族取代反应,进而优先被亲电子性更高的纳米颗粒活化.
Doi:10.1002/anie.201910060

专利信息

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:WO-2009073246-A1
优先权日:2007-12-06
标 题 :Method for the synthesis of iridium (iii) complexes with sterically demanding ligands

专利号:US-2009124805-A1
优先权日:2006-12-08
标题 :Method for synthesis of iriduim (iii) complexes with sterically demanding ligands

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues

专利号:US-8519130-B2
优先权日:2006-12-08
标 题 :Method for synthesis of iriduim (III) complexes with sterically demanding ligands
发明人：ALLEYNE BERT
权利人:ALLEYNE BERT; UNIVERSAL DISPLAY CORP
摘要:Phosphorescent materials and devices with improved device manufacturing, fabrication, stability, efficiency, and/or color.