CAS: 73821-97-3; Boc-Glu(Ochex)-Oh

相似化合物

150047-85-1 73821-95-1 143415-51-4

上下游产品

CAS号56-86-0 L-谷氨酸 | CAS号108-93-0 环己醇 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号112471-82-6 L-谷氨酸-5-环己酯 | CAS号56-86-0 L-谷氨酸 | CAS号2419-94-5 B°C-L-谷氨酸

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于三甲基氢氧化锡体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 10.0H,以100%的收率获得产物n-Boc-L-谷氨酸5-环己基酯
参考文献:氢氧化三甲基锡选择性地分离merrifield,Pam和wang树脂中boc保护的氨基酸和肽
标题:氢氧化三甲基锡选择性地分离merrifield,Pam和wang树脂中boc保护的氨基酸和肽
摘要:我们描述了一种新的非酸解性和非亲核性方法的发展,该方法用于通过三甲基锡氢氧化物选择性地切割氨基酸和二肽在与酯合成中常用的树脂连接的苄基酯键处进行选择性切割.
DOI:10.1016/s0040-4020(98)00805-9

专利信息

专利号:EP-1246837-B1
优先权日:2000-01-11
标 题:Oligomers of nonpeptide restricted mimetics of dipeptides or tripeptides and the use thereof in the synthesis of synthetic proteins and polypeptides
发明人：AMBLARD MURIEL; MARTINEZ JEAN; BERGE GILBERT
权利人:CENTRE NAT RECH SCIENT
摘要:The invention relates to nonpeptide oligomers of amino acids. The oligomers comprise -(NR'-A-CO)-O- units which represent a nonpeptide, restricted-mimetic inducer of the beta turn in a dipeptide or tripeptide fragment. Said oligomers may be produced by peptide synthesis techniques, whether in solution or in the solid phase, and can be used in the synthesis of synthetic proteins or polypeptides, in which the peptide fragment(s) (is) are identical to those of the corresponding natural protein or polypeptide and whose structural fragment(s) comprise(s) a fragment of an oligomer according to the invention.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2003191049-A1
优先权日:2000-01-11
标 题:Oligomers of nonpeptide restricted mimetics of dipeptides of tripeptides, and the use thereof in the synthesis of synthetic proteins and polypeptides

专利号:EP-1246837-A2
优先权日:2000-01-11
标 题:Oligomers of nonpeptide restricted mimetics of dipeptides or tripeptides and the use thereof in the synthesis of synthetic proteins and polypeptides