CAS: 778-28-9; Butyl 4-Methylbenzenesulfonate

该化合物是一种有机磺酸酯,通常用作烷基剂或合成化学的中间体,其主要优点包括其在标准条件下的稳定性及其在核细胞替代反应中的反应性,使其对将丁基分子组引入目标分子具有价值.芳香环上的甲基替代成分增加了其在有机溶剂中的溶解性,便利了在各种反应系统中的处理.该化合物在需要控制对等的精细化学合成中特别有用.其明确界定的结构和可预测的反应性有助于其在实验室和工业应用中的可靠性.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

p-toluenesulfonyl chloride butan-1-ol dibutyl ether acetyl p-toluenesulfonateN-butylpyridine p-toluenesulfonate 1-butyl-3-hydroxy-pyridinium; toluene-4-sulfonate 1-bromo-butane 1-butylbenzene

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-11161827-B2
    优先权日:2019-04-05
    标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
    发明人:Zhang xiao-xiang; Lang kai
    权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
    摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

    专利号:US-10253165-B2
    优先权日:2015-02-26
    标 题 :Control of organic impurities in polycarbonate synthesis
    发明人:BOJARSKI AARON DAVID; GARCIA AGUDO JORGE A
    权利人:SABIC GLOBAL TECHNOLOGIES BV
    摘要:Polymerization processes comprising melt polymerizing a carbonate and a dihydroxy compound in the presence of an amount of a beta organic catalyst so as to give rise to a polycarbonate product, wherein the amount of beta organic catalyst comprises at least one onium salt and also comprises triphenyl phosphonium oxide (TPPO), and wherein the TPPO represents less than about 0.3 weight % of the sum of the weights of the at least one onium salt and the TPPO in the amount of beta organic catalyst.

    专利号:US-4352788-A
    优先权日:1979-08-09
    标题 :Derivatives of 2,4,6-triiodo-isophthalic acid, processes for their synthesis and X-ray contrasting materials containing these
    发明人:FELDER ERNST; PITRE DAVIDE
    权利人:BRACCO IND CHIMICA SPA
    摘要:Compounds for use in non-ionic X-ray contrasting materials having the formula ##STR1## in which (H0) 2-3 alkyl is 1,3-dihydroxyisopropyl, 2,3-dihydroxypropyl or 1,3-dihydroxy-2-hydroxymethylisopropyl, n R is hydrogen or methyl, and n R 1 is an alkyl residue with 1 to 5 carbon atoms. n These compounds possess high water-solubility as well as excellent stability against hydrolysis. Methods for preparation and use of the compounds are also disclosed.

    专利号:WO-2018191612-A1
    优先权日:2017-04-14
    标 题 :Synthesis of a phosphorous containing monomer and the incorporation in polycarbonate by interfacial polymerization thereof

    专利号:US-8841425-B2
    优先权日:2003-05-20
    标 题:Cytotoxic agents comprising new maytansinoids
    发明人:CHARI RAVI V J; WIDDISON WAYNE C
    权利人:CHARI RAVI V J; WIDDISON WAYNE C; IMMUNOGEN INC
    摘要:New thiol and disulfide-containing maytansinoids bearing a mono or di-alkyl substitution on the α-carbon atom bearing the sulfur atom are disclosed. Also disclosed are methods for the synthesis of these new maytansinoids and methods for the linkage of these new maytansinoids to cell-binding agents. The maytansinoid-cell-binding agent conjugates are useful as therapeutic agents, which are delivered specifically to target cells and are cytotoxic. These conjugates display vastly improved therapeutic efficacy in animal tumor models compared to the previously described agents.

    专利号:US-2020048410-A1
    优先权日:2017-04-14
    标 题:Synthesis of a phosphorous containing monomer and the incorporation in polycarbonate by interfacial polymerization thereof
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    合成参考文献


    摘要:Zeitschrift fuer Krebsforschung., 74(241), 1970 []
    摘要:Summary Tables of Biological Tests, National Research Council Chemical-Biological Coordination Center., 2(303), 1950
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#01764
    摘要:Harmata, M., Science of Synthesis, (2007) 25, 457.
    摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 800.
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