CAS: 140-67-0; 1-Allyl-4-Methoxybenzene

该化合物是一种有机化合物,被归类为苯丙烯,是一种芳香化合物,其特点是香味和香味,通常存在于基本油类中,特别是在焦拉松和巴西里.埃斯特拉戈勒的分子配方为C10H12O,并配有一种配有氯乙烯组的甲氧基组,有助于其独特的芳香.这种化合物在室内温度下是粉黄液体的无色,可溶于有机溶剂,但水溶性有限.埃斯特拉戈经常用于食品和香味行业的调味和香味.然而,必须指出的是,已经研究过斯特拉戈尔的潜在致癌效应,导致在某些地区进行监管检查.与许多芳香化合物一样,应该谨慎处理,考虑到其潜在健康影响和使用中适当的安全措施的必要性.

结构式图片

相似化合物

140-67-0 24743-14-4 1515-95-3

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

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CAS号104-92-7 对溴苯甲醚 | CAS号106-95-6 烯丙基溴 | CAS号623-12-1 4-氯苯甲醚 | CAS号24850-33-7 烯丙基三丁基锡 | CAS号591-87-7 乙酸烯丙酯 | CAS号696-62-8 4-碘苯甲醚 | CAS号1092390-58-3 sodium 1,1-dime... | CAS号107-05-1 氯丙烯 | CAS号762-72-1 烯丙基三甲基硅烷 | CAS号15183-74-1 1-METHOXY-4-TRI... | CAS号4521-28-2 4-(4-甲氧基苯基)丁酸 | CAS号100-09-4 对甲氧基苯甲酸 | CAS号104-01-8 4-甲氧基苯乙酸 | CAS号104-45-0 对丙基苯甲醚 | CAS号5462-06-6 4-甲氧基-Alpha-甲基苯丙醛 | CAS号56047-51-9 4-甲氧基苯丁醛 | CAS号4180-23-8 茴香烯 | CAS号25679-28-1 (Z)-anethol | CAS号501-92-8 4-烯丙基苯酚 | CAS号20637-08-5 4-(4-甲氧基苯基)丁酸甲酯

合成工艺路线路线简述

    反式-4-甲氧基肉桂酸置于吡啶,Lithium Aluminium Tetrahydride,乙醚体系中,化学反应生成4-烯丙基苯甲醚
    参考文献:Recombinant Human Bone Morphogenetic Protein-2 Enhances Osteotomy Healing In Glucocorticoid-Treated Rabbits
    标题:Recombinant Human Bone Morphogenetic Protein-2 Enhances Osteotomy Healing In Glucocorticoid-Treated Rabbits
    摘要:本研究的目的是评估慢性泼尼松龙治疗对兔子截骨愈合的影响,并确定重组人骨形态发生蛋白-2 (Rhbmp-2) 在长期糖皮质激素治疗的情况下是否会增强愈合. 49 只骨骼成熟的雄性兔子被注射泼尼松龙(n = 26;每天 0.35 Mg/kg,每周 3 次)或盐水(n = 23).经过 6 周的预处理期后,通过手术进行了双侧尺骨截骨术.其中一个截骨术采用可吸收拼贴海绵 (Acs) 上的 Rhbmp-2(0.2 Mg/ml Rhbmp-2,总共 40 μg Rhbmp-2)进行治疗,而对侧截骨术则未进行治疗.持续泼尼松龙或盐水治疗直至截骨后6周或8周处死兔子.通过放射线照相,外周定量计算机断层扫描 (Pqct),扭转生物力学和未脱钙组织学评估截骨愈合情况.由于我们在 6 周和 8 周队列中观测到泼尼松龙和 Rhbmp-2/acs 治疗的相似反应,因此将这些时间点的结果合并.泼尼松龙治疗的兔子的血清骨钙素和椎骨小梁密度较低.泼尼松龙治疗显着抑制截骨愈合.在未经治疗的尺骨中,接受泼尼松龙治疗的兔子的愈伤组织面积和扭转强度分别比盐水组小 25% 和 55%(两者的 P < 0.001). Rhbmp-2/acs 增强了泼尼松龙治疗组和盐水治疗组的愈合能力,尽管泼尼松龙治疗组的效果更大.在泼尼松龙治疗的兔子中,与对侧未经治疗的截骨术相比,用 Rhbmp-2/acs 治疗的截骨术中愈伤组织面积和扭转强度分别大 40% 和 165%(两者 P < 0.001).组织学评估证实,泼尼松龙抑制截骨愈合,Rhbmp-2/acs 加速截骨愈合.总之,单次应用 Rhbmp-2/acs 可以抵消泼尼松龙暴露引起的截骨愈合抑制.这些结果表明,Rhbmp-2/acs 可能是促进长期接受糖皮质激素治疗的患者骨折愈合的有效治疗方法.
    Doi:10.1359/jbmr.2002.17.2.301

    海关参考信息

    专利信息


    专利号:US-11306041-B2
    优先权日:2017-03-30
    标 题:Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts
    发明人:SCHINSKI WILLIAM; GOLDMAN ALAN; GUNNOE THOMAS B; WEBSTER-GARDINER MICHAEL S; SCHWARTZ NICHOLE
    权利人:UNIV VIRGINIA PATENT FOUNDATION
    摘要:Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN).

    专利号:US-2023174477-A1
    优先权日:2021-12-03
    标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester
    发明人:DAI MINGJI; SIMS HUNTER
    权利人:PURDUE RESEARCH FOUNDATION
    摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.

    专利号:WO-2024130393-A1
    优先权日:2022-12-21
    标 题 :Nanoparticle and method of synthesis thereof
    发明人:MOSKOVCHENKO SVITLANA
    权利人:MOSKOVCHENKO SVITLANA
    摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.

    专利号:US-7253324-B1
    优先权日:2007-01-23
    标 题:Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers
    发明人:MAJEED MUHAMMED; THOMAS SAMUEL MANOHARAN; NAGABHUSHANAM KALYANAM; BALAKRISHNAN SIVAPRAKASH KURUM; PRAKASH SUBBALAKSHMI
    权利人:SAMI LABS LTD
    摘要:Alkoxy aromatic compounds are conveniently dealkylated to the corresponding phenolic compounds by treatment with aluminum chloride/N,N-dimethyl aniline complex. Aromatic poly O-demethylation is a unique feature of this invention. This process is applicable to the manufacture of polyphenols such as Resveratrol, Oxyresveratrol, Gnetol.

    专利号:US-6448412-B1
    优先权日:1995-07-31
    标题:Methods for the preparation and characterization of multi-substituted fullerenes
    发明人:MURPHY RANDALL B; WILSON STEPHEN R; LU QUING
    权利人:SPHERE BIOSYSTEMS INC
    摘要:The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a library of fullerene derivatives and comprises the steps of forming a mixture of fullerene derivatives by reacting the C n fullerene with two or more reactive precursor compounds, and removing the unreacted compounds to yield the fullerene derivatives having the desired activity. Methods for the identification and screening of a combinatorial library of fullerenes by 3 He-nuclear magnetic resonance and electrospray mass spectrometry to define members with the optimal desired activity are also provided.

    专利号:US-8927776-B2
    优先权日:2010-11-08
    标题 :Method for hydroformylation of unsaturated compounds
    发明人:FRANKE ROBERT; BELLER MATTHIAS; JACKSTELL RALF; JENNERJAHN REIKO; PIRAS IRENE
    权利人:FRANKE ROBERT; BELLER MATTHIAS; JACKSTELL RALF; JENNERJAHN REIKO; PIRAS IRENE; EVONIK DEGUSSA GMBH
    摘要:The invention relates to a method for hydroformylation of unsaturated compounds such as olefins and alkynes using mixtures of synthesis gas (CO/H 2 ), in which either the unsaturated compounds and a catalyst are heated to a reaction temperature of 60 to 200° C. and the synthesis gas is then added, or the unsaturated compounds and the catalyst are brought into contact with pure CO at normal temperature in a preformation step, then are heated to reaction temperature and on reaching the reaction temperature the CO is replaced by the synthesis gas. The pressure is 1 to 200 bar and the CO:H 2 ratio in the synthesis gas is in the range from 1:1 to 50:1. The iridium catalyst used comprises a phosphorus-containing ligand in the iridium:ligand ratio in the range from 1:1 to 1:100. With high catalyst activities and low catalyst use, very high turnover frequencies are achieved.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Liang L, Zhang W, Hao J, Wang Y, Wei S, Zhang S, Hu Y, Lv Y. Estragole Inhibits Growth and Aflatoxin Biosynthesis of Aspergillus flavus by Affecting Reactive Oxygen Species Homeostasis. Microbiol Spectr. 2023 Aug 17;11(4):e0134823. doi: 10.1128/spectrum.01348-23. Epub 2023 Jun 8.
    2: Shivaramu S, Parepally SK, Byregowda VY, Pagadala Damodaram KJ, Bhatnagar A, Naga KC, Sharma S, Kumar M, Kempraj V. Estragole, a potential attractant of the winged melon aphid Aphis gossypii. Pest Manag Sci. 2023 Jul;79(7):2365-2371. doi: 10.1002/ps.7413. Epub 2023 Mar 9.
    444:152566. doi: 10.1016/j.tox.2020.152566. Epub 2020 Aug 25.

    合成参考文献


    摘要:Diver, S. T., Science of Synthesis, (2009) 46, 135.
    摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 63.
    摘要:Tsukamoto, M.; Kitamura, M., Science of Synthesis, (2009) 48, 350.
    摘要:Sartori, G.; Maggi, R., Science of Synthesis, (2010) 47, 520.
    摘要:Okamoto, K.; Ohe, K., Science of Synthesis Knowledge Updates, (2020) 1, 119.
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