CAS: 21286-54-4; ((1S,4R)-7,7-Dimethyl-2-Oxobicyclo[2.2.1]Heptan-1-yl)Methanesulfonyl Chloride

相似化合物

3144-16-9 35963-20-3 5872-08-2

上下游产品

CAS号3144-16-9 右旋樟脑磺酸 | CAS号77541-94-7 acide S(+)-10-c... | CAS号464-49-3 D(+)-樟脑 | CAS号94594-81-7 (S)-(+)-(2-丁烯酰)... | CAS号184850-95-1 (4S)-7,7-dimeth... | CAS号94594-90-8 左旋樟脑磺内酰胺 | CAS号464-49-3 D(+)-樟脑 | CAS号60886-80-8 (-)-10-樟脑内磺酰亚胺 | CAS号71242-58-5 (1S)-(-)-10-巯基异冰片 | CAS号71242-59-6 (1S)-(-)-10-巯基冰片 | CAS号60933-63-3 (1S)-10-樟脑内磺酰胺 | CAS号464-78-8 酮基蒎酸 | CAS号107869-45-4 (+)-10-樟脑磺内酰亚胺

D(+)-10-樟脑磺酸置于三氯乙腈,三苯基膦体系中,用 二氯甲烷 用作溶剂,化学反应 1.0H,反应生成右旋樟脑-10-磺酰氯
参考文献:一种实用有效的利用cl 3 Ccn / Pph 3制备磺酰胺的方法
标题:一种实用有效的利用cl 3 Ccn / Pph 3制备磺酰胺的方法
摘要:Cl 3 Ccn与pph 3的结合被证明是一种高反应性的试剂,可在回流的ch 2 Cl 2中将磺酸转化为相应的磺酰氯.与胺反应后,以非常好至优异的收率获得相应的磺酰胺.
Doi:10.1016/j.Tetlet.2006.08.036

专利信息

专利号:EP-0839142-B1
优先权日:1995-07-13
标题 :A novel asymmetric synthesis of r and s warfarin and its analogs
发明人：LI HUI-YIN; ROBINSON ANDREA JANE
权利人:DU PONT PHARM CO
摘要:The present invention provides a novel process for making compounds of formula (2a or 2b) or pharmaceutically acceptable salts thereof, wherein R1 is selected from the group consisting of phenyl and phenyl substituted with at least one group selected from NO2 and halogen, R2 is H; R3 is selected from the group consisting of C1-4 alkyl, phenyl, and benzyl; and, R4 is selected from the group consisting of H and halogen; which comprises the steps of: a) oxidizing a racemate of formula (2) or a salt thereof to form a dehydro-compound of formula (3), wherein R5 is selected from the group consisting of H, CH3, benzyl, C2-8 acyl, Na, Li and K; and, b) asymmetrically hydrogenating a compound of formula (3) in the presence of a chiral phosphine catalyst to form a compound of formula (2a or 2b).

专利号:CA-2960437-A1
优先权日:2014-09-10
标 题 :Synthesis of isoflavanes and intermediates thereof

专利号:JP-4063320-B2
优先权日:1995-07-13
标题 :Novel asymmetric synthesis of R and S warfarin and similar compounds

专利号:US-2017283389-A1
优先权日:2014-09-10
标题 :Synthesis of Isoflavanes and Intermediates Thereof

专利号:DE-69615200-T2
优先权日:1995-07-13
标题:ASYMETRIC SYNTHESIS OF R AND S WARFARIN AND THEIR SIMILAR COMPOUNDS

专利号:US-5686631-A
优先权日:1995-07-13
标题 :Asymmetric synthesis of R and S warfarin and its analogs