CAS: 23597-82-2; Hexyl Nicotinate

该化合物是安全的,尽管与许多化合物一样,可能会引起敏感个人的愤怒;其在有机溶剂中的溶解性以及水溶性有限,进一步界定了其在各种配方中的用途.总的来说,乙基尼科丁在化妆品和个人护理行业中是一种多功能成分.

结构式图片

相似化合物

6938-06-3 614-18-6 20826-02-2

欧盟法规

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上下游产品

CAS号20260-53-1 盐酸烟酰氯 | CAS号111-27-3 正己醇 | CAS号59-67-6 烟酸 | CAS号490-11-9 吡啶-3,4-二羧酸

合成工艺路线路线简述

  • 合成目标产物 Hexyl Nicotinate 主要起始原料 3,4-Pyridinedicarboxylic Acid And 1-Hexanol
  • (文献来源)合成步骤主要原料 3,4-Pyridinedicarboxylic Acid 和 1-Hexanol
烟酸置于吡啶,氯化亚砜体系中,化学反应生成烟酸己酯
参考文献:Nicotinic Acid. Water-Insoluble Esters And Amides
标题:Nicotinic Acid. Water-Insoluble Esters And Amides
摘要:
Doi:10.1021/ja01223A028

海关参考信息

专利信息


专利号:US-4568676-A
优先权日:1983-11-25
标题:Method of inhibiting aggregation using thromboxane synthetase inhibitor in combination with a cyclic AMP phosphodiesterase inhibitor
发明人:SMITH J BRYAN
权利人:UNIV JEFFERSON
摘要:A novel method of inhibiting blood platelet aggregation is disclosed which comprises the use of a CAMP inhibitor together with an inhibitor of thromboxane synthesis. While inhibitors of thromboxane synthesis are only weak inhibitors of platelet aggregation, the addition of only a small amount of a CAMP inhibitor has been found to result in a synergistic increase in the degree of platelet aggregation resulting from such combined additions. Marked increases over the otherwise expected culumative effects of these inhibitors have been demonstrated using combination of various thromboxane synthetase inhibitors and various CAMP inhibitors.

专利号:CA-2640585-A1
优先权日:2003-02-05
标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one

专利号:US-2004146539-A1
优先权日:2003-01-24
标 题:Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
发明人:GUPTA SHYAM K
摘要:I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA/UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, “love handlesâ€? in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery ystem.

专利号:US-8354116-B2
优先权日:2007-06-18
标题 :Bifunctional synthetic molecules
发明人:CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
权利人:BIOCHEMICS INC; CARTER STEPHEN G; PATEL KANU; ZHU ZHEN; QIAO LIXIN
摘要:The synthesis and use of bifunctional molecules to improve the topical and transdermal delivery efficiency of various types of therapeutic agents or agents designed to promote the transdermal delivery of those therapeutic agents either into the skin tissue or into the systemic circulation. Three major classes of molecules are covalently joined as bifunctional substances; chemical vasodilators, passive dermal penetration enhancers and therapeutic or diagnostic drugs. Chemical vasodilators may be delivered into the skin to increasing the blood flow in a tissue that has compromised circulation or they may be used as part of a delivery vehicle to promote the delivery of the drug. Passive dermal penetration enhancers are those chemicals that promote the passive penetration of drugs and other chemicals through the stratum corneum and epidermis of the skin tissue. Drugs and diagnostic agents are the third group of chemicals that are candidates for the linkage of molecules.

专利号:CN-107224436-A
优先权日:2017-06-23
标题 :A class of twin-drug HMG-CoA reductase inhibitors and its synthesis method
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主要参考文献


1: Zhai H, Zheng Y, Fautz R, Fuchs A, Maibach HI. Reactions of non-immunologic contact urticaria on scalp, face, and back. Skin Res Technol. 2012 Nov;18(4):436-41. doi: 10.1111/j.1600-0846.2011.00590.x. Epub 2011 Nov 9. doi: 10.1111/j.1600-0846.2009.00400.x. doi: 10.1080/09546630802512679. doi: 10.1002/bdd.610.

合成参考文献


摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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