CAS: 2921-14-4; O-(Carboxymethyl)Hydroxylamine Hemihydrochloride

该化合物是化学化合物,其特点是有矿物质功能组和碳酸衍生物,通常被作为白色和白外晶状粉,由于存在极地功能组,在水中可溶解;该化合物经常用于有机合成,并可作为生产药品或农用化学品的一个中间体;其六氟化碳形式表明它是一种盐,可以影响其稳定性和溶性性;碳化物和矿物质组的存在允许各种化学再活动,包括可能参与凝聚反应和形成氨;在处理和储存准则时,应参考安全数据表,与任何化学物质一样,以确保采取适当的安全措施;总的来说,碳化汞氧盐氢氯化物是一种多种化合物,在研究和工业中应用,特别是在合成更复杂的分子方面.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于盐酸体系中,化学反应生成羧甲基羟胺半盐酸盐
    参考文献:Kitagawa; Takani,Journal Of Biochemistry,1936,Vol. 23,P. 181,182
    标题:Kitagawa; Takani,Journal Of Biochemistry,1936,Vol. 23,P. 181,182

    海关参考信息

    专利信息


    专利号:US-7884182-B2
    优先权日:2001-11-14
    标 题 :Chemical peptide ligation with three or more components
    发明人:BOTTI PAOLO; GAERTNER HUBERT; MANGANIELLO SONIA; VILLAIN MATTEO
    权利人:AMYLIN PHARMACEUTICALS INC
    摘要:The invention provides a method of assembling oligopeptide intermediates in a native chemical ligation reaction that eliminates self-ligation of bi-functional intermediates. An important aspect of the invention is a bi-functional intermediate with an N-terminal heterocyclic protecting group which effectively prevents self-ligation in the chemical assembly process. The present invention is useful in methods for convergent synthesis of polypeptides and proteins and improves the efficiency of native chemical ligation reactions, particularly where three or more peptide fragments are used to assemble a polypeptide or protein product.

    专利号:ES-2249986-B1
    优先权日:2004-07-02
    标 题 :SYNTHESIS OF FLUORESCENT DERIVATIVES OF TACROLIMUS (FK506) AND ITS USE IN THE CHARACTERIZATION OF THE INTERACTION OF FK506 WITH PROTEINS UNION TO FK506.

    专利号:ES-2249986-A1
    优先权日:2004-07-02
    标 题 :Synthesis of fluorescent derivatives of tacrolimus (FK506) consists of a cellular interaction promotion and proteins based union technique

    专利号:CN-103626693-A
    优先权日:2012-08-28
    标 题 :A class of pleuromutilin derivatives, its pharmaceutical composition and its synthesis method and application

    专利号:RU-2024527-C1
    优先权日:1986-03-25
    标 题 :Method of macrolide compounds synthesis
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    主要参考文献


    1: Carmona E, Gomes C, Trolin G. Effect of aminooxyacetic acid (AOAA) on GABA levels in some parts of the rat brain. Naunyn Schmiedebergs Arch Pharmacol. 1980 May;312(1):51-5.
    4: van der Laan JW, Weick G, van Bleek G. Effects of inhibitors of GABA-transaminase on hole-board exploration and on temperature. Relation with effects on quasi-morphine abstinence behaviour induced by sodium dipropylacetate. Biochem Pharmacol. 1985 Nov 1;34(21):3789-94. Epub 2006 Mar 3. doi: 10.1007/s11010-012-1257-3. Epub 2012 Feb 18.

    合成参考文献


    摘要:Journal of Medicinal and Pharmaceutical Chemistry., 5(464), 1962
    参考文献:10.1186/1744-8069-8-89
    摘要:Li L, Xie R, Hu S, Wang Y, Yu T, Xiao Y, Jiang X, Gu J, Hu CY, Xu GY. Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation. Mol Pain. 2012 Dec 18;8():89.
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