CAS: 455-01-6; 2-(3-(Trifluoromethyl)Phenyl)Ethanol

上下游产品

CAS号351-35-9 3-(三氟甲基)苯乙酸 | CAS号395-45-9 邻三氟甲基苯乙烯 | CAS号402-24-4 3-(三氟甲基)苯乙烯 | CAS号75-21-8 环氧乙烷 | CAS号402-26-6 间(三氟甲基)苯基溴化镁 | CAS号2338-76-3 间三氟甲基苯乙腈 | CAS号705-29-3 3-三氟甲基氯苄 | CAS号62451-84-7 3-三氟甲基苯乙酸甲酯 | CAS号402-24-4 3-(三氟甲基)苯乙烯 | CAS号21172-31-6 2-(3-(三氟甲基)苯基)乙醛 | CAS号1997-80-4 1-(2-溴乙基)-3-(三氟甲基)苯 | CAS号402-35-7 1-(2-氯乙基)-3-(三氟甲基)苯

3-三氟甲基苯乙酸甲酯置于三乙基硼氢化钠,Sodium Hydroxide体系中,用 乙醚,甲苯,甲醇 作为反应溶剂,化学反应 10.0H,以95%的收率获得产物3-(三氟甲基)苯乙醇
参考文献:一般实用的三乙基硼烷催化的羰基官能团还原为醇
标题:一般实用的三乙基硼烷催化的羰基官能团还原为醇
摘要:大量廉价的三乙基硼烷与烷醇钠的组合可反应生成一种高效催化剂,用于在温和条件下使用廉价的氢化硅烷将酯以及酮和醛还原为醇.该催化剂体系表现出优异的化学选择性和高水平的官能团耐受性.机理研究表明,三乙基烷氧基棉酸钠的静置状态是bet 3与醇钠反应的产物.该硼酸盐物质与氢硅烷反应形成nabet 3 H,这会迅速还原酯.
DOI:10.1002/chem.201502942

专利信息

专利号:US-2005240034-A1
优先权日:2002-05-07
标 题 :Artemisinin-based peroxide compounds as broad spectrum anti-infective agents
发明人：AVERY MITCHELL; MURALEEDHARAN KANNOTH M
权利人:AVERY MITCHELL; MURALEEDHARAN KANNOTH M
摘要:Described herein is the synthesis, bioassay results and utility of new C- 9 and C- 10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.

专利号:CN-111807971-A
优先权日:2020-07-09
标 题 :Alkylation synthesis method for in-situ catalysis of alcohols

专利号:CN-111807971-B
优先权日:2020-07-09
标题 :Alkylation synthesis method of a kind of in-situ catalytic alcohols