CAS: 455-13-0; 4-Iodobenzotrifluoride

上下游产品

CAS号98-08-8 三氟甲苯 | CAS号5122-99-6 4-碘苯硼酸 | CAS号2926-29-6 三氟代甲烷亚磺酸钠 | CAS号402-43-7 对溴三氟甲苯 | CAS号2314-97-8 三氟碘甲烷 | CAS号98-56-6 4-氯三氟甲苯 | CAS号591-50-4 碘苯 | CAS号81290-20-2 (三氟甲基)三甲基硅烷 | CAS号185515-88-2 hexakis[4-(trif... | CAS号402-54-0 4-硝基三氟甲苯 | CAS号101466-85-7 3-(4-(三氟甲基)苯基)丙烯酸乙酯 | CAS号108789-37-3 1-benzylsulfany... | CAS号35779-04-5 1-叔丁基-3-碘苯 | CAS号455-14-1 4-氨基三氟甲苯 | CAS号34898-30-1 2-[4-(三氟甲基)苯基]-1H-咪唑 | CAS号362601-71-6 3-(4-三氟甲基苯基)-1H-吡唑 | CAS号329-15-7 对三氟甲基苯甲酰氯 | CAS号583-02-8 4-(三氟甲基)苯甲酸乙酯 | CAS号455-24-3 4-三氟甲基苯甲酸 | CAS号329-14-6 4-三氟甲基茴香硫醚

4-硝基三氟甲苯置于盐酸,Tin(Ll) Chloride体系中,化学反应生成 4-碘三氟甲苯
参考文献:Jones,Journal Of The American Chemical Society,1947,Vol. 69,P. 2352
标题:Jones,Journal Of The American Chemical Society,1947,Vol. 69,P. 2352

专利信息

专利号:US-10487099-B2
优先权日:2017-06-30
标 题:Synthesis of hypervalent iodine reagents with dioxygen
发明人：POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN
权利人:TEXAS A & M UNIV SYS
摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:WO-2024206300-A1
优先权日:2023-03-27
标题 :Synthesis of a hippo-yap pathway modulator and a polymorph thereof
发明人：KONRADI ANDREI W; WILSON JO ANN ZBUR; ZELLER JAMES ROBERT
权利人:VIVACE THERAPEUTICS INC
摘要:Described herein is the preparation of a Hippo-YAP pathway modulator and chemical intermediates used in the synthetic process. Also described herein is a polymorph of a Hippo-YAP pathway modulator.

专利号:US-11542283-B2
优先权日:2018-05-28
标题 :Synthesis of peptide borate ester compound and use thereof
发明人：QIN YANRU
权利人:JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO LTD
摘要:Provided are a peptide borate ester compound or a pharmaceutically acceptable salt thereof, a preparation method therefor, and pharmaceutical use thereof. The peptide borate ester compound or pharmaceutically acceptable salt thereof has a structure as shown in Formula (I), and is useful in the preparation of proteasome inhibitors to treat solid tumors and hematoma.

专利号:US-5998627-A
优先权日:1997-08-04
标题 :Preparation and uses of hydrocarbylnitrones
发明人：THERIOT KEVIN J
权利人:ALBEMARLE CORP
摘要:Nitrones are produced by reaction of primary amine with aldehyde or ketone, in the presence of a transition metal-containing oxidation catalyst, and a peroxidic compound. The nitrone can then be reacted with a vinylaromatic compound to produce a 2-hydrocarbyl-5-arylisoxazolidine. Both such reactions can be conducted concurrently by including the vinylaromatic compound in the initial reaction mixture. Hydrogenation of the 2-hydrocarbyl-5-arylisoxazolidine, e.g., using hydrogen and a palladium-carbon catalyst, forms an N-hydrocarbyl-3-aryl-3-hydroxypropylamine. Such reactions enable, inter alia, synthesis of the racemic hydrochloride salt of N-methyl-3-phenyl-3-[4-trifluoromethyl)phenoxy]-propylamine, known generically as fluoxetine hydrochloride, a widely used antidepressant.

专利号:US-8013157-B2
优先权日:2006-12-20
标题:Synthesis of unsaturated piperidines from piperidones with a silyl reagent
发明人：MANI NEELAKANDHA S; MORRILL CHRISTIE
权利人:JANSSEN PHARMACEUTICA NV
摘要:Syntheses of unsaturated piperidines from piperidones through a silyl piperidine reagent via the Shapiro reaction and palladium-catalyzed cross-coupling reactions with organo halides.