专利号:US-2018333433-A1 优先权日:2017-05-18 标题 :Synthesis of silver nanoparticles using sesame oil cake 发明人:ALSALHI MOHAMAD SALEH; DEVANESAN SANDHANASAMY; ALFURAYDI AKRAM AHMED; AL-ANSARI MYSOON M F 权利人:UNIV KING SAUD 摘要:A method of synthesizing silver nanoparticles includes using sesame ( Sesamum indicum ) oil cake extract as a reducing agent. The silver nanoparticles can range in size from about 6 nm to about 15 nm. The silver nanoparticles can have an average particle size of about 10 nm.
专利号:US-2025164360-A1 优先权日:2022-06-09 标 题:On-slide synthesis of a schiff reagent 发明人:BIRD JEAN MARIE; CANTORIA MARY JO CASTRO; DURRANT EDWARD E; HANNON ANDREW 权利人:VENTANA MED SYST INC 摘要:The present disclosure is directed to compositions, kits, and methods for synthesizing a Schiff's reagent in situ, i.e., directly on a substrate, such as within a puddle disposed on the surface of a substrate. In some embodiments, the kits comprise at least a dye composition and a sulfite composition. In some embodiments, the dye composition comprises a compound having a 4-Benzhydrylidene-2,5-cyclohexadien-1-imine core functionalized to include at least two substituted or unsubstituted amine groups, wherein the compound has a molecular weight ranging from between about 300 g/mol to about 600 g/mol. In some embodiments, the dye composition optionally includes an acid. In some embodiments, the sulfite composition comprises a sulfite or SO2 source.
专利号:US-2008194678-A1 优先权日:2005-07-15 标 题:Process To Obtain Synthetic And Semi-Synthetic Lignan Derivatives, Their Antiparasitic Activities And Corresponding Pharmaceutical Formulations, Including The Therapeutic Method Using Said Lignan For The Treatment Of Parasitosis 发明人:SILVA MARCIO LUIS ANDRADE E; SILVA ROSANGELA DA; RODRIGUES VANDERLEI; PEREIRA OLAVO DOS SANTOS; SILVA FILHO ADEMAR ALVES DA; DONATE PAULO MARCOS; ALBUQUERQUE SERGIO; BASTOS JAIRO KENUPP 权利人:FUNDACAO DE AMPARO A PESQUISSA 摘要:A process to obtain synthetic and semi-synthetic derivatives of lignans, especially dibenzylbutyrolactonic, tetrahydrofuranic, aryltetralynic, furofuranic and dibenzocyclooctanic lignans obtained by means of partial synthesis and/or full synthesis or also by isolation from plant extracts. It refers to a process to obtain synthetic and semi-synthetic derivatives of (−)-cubebin, such as: (−)-O-acetylcubebin; (−)-O-methylcubebin; (−)-O—N,N-(dimethylamino-ethyl)-cubebin; (−)-hinokinin; (−)-6,6′-dinitroinokinine; (−)-O-benzylcubebin; (−)-6,6′-diaminoinokinin, (−)-6,6′-dinitroinokinin, as well as to obtain dibenzocyclooctanic lignans from dibenzylbutyrolactoinic lignans by means of structural modifications in the positions 7, 7′, 8, 8′, 9′ and in the aromatic rings (introduction and/or substitution of functional groups such as: —OH, —CO 2 H, —CO 2 CH 3 , —NO 2 , —NH 2 , —OCH 3 , —OAc, —SO 2 CH 3 , —SO 2 NH 2 , prenyl and halogens) is provided. A therapeutic method using the derivatives is also provided.
专利号:US-12187735-B2 优先权日:2018-09-17 标 题:Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease 发明人:LING XIANG; LI QINGYONG; LI FENGZHI 权利人:CANGET BIOTEKPHARMA LLC 摘要:Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.
专利号:US-2025092058-A1 优先权日:2018-09-17 标 题 :Matter of composition, synthesis, formulation and application of fl 118 platform positions 7 and 9-derived analogues for treatment of human disease 发明人:LING XIANG; LI QINGYONG; LI FENGZHI 权利人:CANGET BIOTEKPHARMA LLC 摘要:Described herein, are the chemical synthesis, compounds, methods and uses of the fluoroaryl-substituted derivatives at the FL118 position 7, which target multiple cellular human disease-relevant proteins and their signaling pathways.
专利号:CN-110184247-B 优先权日:2019-05-09 标 题:Melatonin synthesis gene MsASMT in alfalfa and its application in regulating the synthesis of melatonin and flavonoids in plants
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