CAS: 6346-09-4; 4,4-Diethoxybutan-1-Amine

相似化合物

114094-45-0 41365-75-7 19060-15-2

上下游产品

CAS号18381-45-8 3-氰基丙醛二乙基缩醛 | CAS号10602-36-5 4,4-二乙氧基-1-丁烯 | CAS号122-51-0 原甲酸三乙酯 | CAS号35573-93-4 3-氯丙醛二乙基乙缩醛 | CAS号13269-77-7 环氧丙烯醛缩二乙醇 | CAS号143706-30-3 4,4-Diethoxy-3-... | CAS号4307-98-6 2-(1-苄基-1H-吲哚-3... | CAS号144035-23-4 5-(1H-1,2,4-三唑-... | CAS号3764-94-1 5-氯靛胺盐酸盐 | CAS号220803-77-0 N-(4,4-二乙氧基丁基)-甲酰胺 | CAS号22375-73-1 N-乙酰基-6-甲氧基色胺 | CAS号88919-22-6 3-(2-氨基乙基)-N-甲基... | CAS号86658-78-8 (2-INDOL-3-YLET... | CAS号7518-21-0 2-(1-甲基-1H-吲哚-3-基)乙胺 | CAS号530-53-0 脱氧鸭嘴花碱酮 | CAS号61-54-1 色胺

3-氯丙醛二乙醇缩醛置于sodium Ethanolate体系中,用 乙醇,二甲基亚砜 作为反应溶剂,化学反应生成 4-氨基丁醛缩二乙醇
参考文献:Anderson,E.; Capon,B.,Journal Of The Chemical Society. Perkin Transactions Ii,1972,P. 515-522
标题:Anderson,E.; Capon,B.,Journal Of The Chemical Society. Perkin Transactions Ii,1972,P. 515-522

专利信息

专利号:US-7491520-B2
优先权日:2004-01-19
标题 :Biochemical synthesis of 6-amino caproic acid
发明人：RAEMAKERS-FRANKEN PETRONELLA C; NOSSIN PETRUS M M; BRANDTS PAUL M; WUBBOLTS MARCEL G; PEETERS WIJNAND P H; ERNSTE SANDRA; WILDEMAN DE STEFAAN M A; SCHUERMANN MARTIN
权利人:DSM IP ASSETS BV
摘要:The invention relates to biochemical synthesis of 6-amino caproic acid from 6-aminohex-2-enoic acid compound or from 6-amino-2-hydroxyhexanoic acid, by treatment with an enzyme having α,β-enoate reductase activity towards molecules containing an α,β-enoate group and a primary amino group. The invention also relates to processes for obtaining suitable genetically engineered cells for being used in such biotransformation process, and to precursor fermentation of 6-amino caproic acid from intermediates leading to 6-amino caproic acid. Finally, the invention relates to certain novel biochemically produced compounds, namely 6-aminohex-2-enoic acid, 6-aminohexanoic acid, as well as to caprolactam produced therefrom and to nylon-6 and other derivatives produced from such biochemically produced compounds or caprolactam.

专利号:US-5219988-A
优先权日:1989-02-22
标 题 :Gem-diamino derivatives and their use in the synthesis of retro-inverso peptides
发明人：GAZERRO LAURA; PINORI MASSIMO; VERDINI ANTONIO S
权利人:ENIRICERCHE SPA; SCLAVO SPA
摘要:This invention relates to new gem-diamino derivatives of general formula (I) ##STR1## where R is the side chain of an amino acid, of which any functional groups are suitably protected, and n X is an acyl group chosen from the group consisting of 2-nitrobenzoyl, 4-chloro-butyryl, acetoacetyl, 4-bromo-butyryl, (2-nitrophenoxy)-acetyl and 2-methyl-2-(2'-nitro-phenoxy)propionyl, of use in introducing gem-diamino residues into retro-inverso peptides. The invention further relates to a method for the synthesis of retro-inverso peptides in which the gem-diamino residue or residues are introduced using the new compound (I).

专利号:US-9034624-B2
优先权日:2009-06-16
标 题 :Process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules, polymeric conjugates and relative uses thereof
发明人：D ESTE MATTEO; RENIER DAVIDE; PASUT GIANFRANCO; ROSATO ANTONIO
权利人:D ESTE MATTEO; RENIER DAVIDE; PASUT GIANFRANCO; ROSATO ANTONIO; FIDIA FARMACEUTICI
摘要:The present invention relates to a process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules of varying nature, comprising small molecules and macro-molecules. In particular, the present invention relates to the conjugation of hyaluronic acid (HA) and its derivatives with polypeptides and proteins with a biological action, such as, for example, interferons, erythropoietins, growth factors, insulin, cytokines, antibodies and hormones. n An object of the present invention also relates to isolatable intermediates obtained by the partial or total reaction of GAG with protected amino aldehydes in the conjugation process mentioned above.

专利号:US-5116947-A
优先权日:1988-12-23
标题:Process for the preparation of retro-inverso peptides and new intermediates thereof
发明人：PINORI MASSIMO; CENTINI FELICE; VERDINI ANTONIO S
权利人:SCLAVO SPA
摘要:A method of synthesis of a partially retro-inverso peptide incorporating at least one malonyl residue of formula (III) ##STR1## wherein R represents the side chain of an α-amino acid, is described which is characterized in that said malonyl residue is incorporated by condensing a 5-substituted-2,2-dimethyl-1,3-dioxane-4,6-dione of formula (IV) ##STR2## wherein R' is the side-chain R wherein the functional groups, if any, are suitably protected, with an amino acid, amino acid amide, peptide fragment, or pseudo-peptide fragment wherein the terminal carboxyl group, if present, and the possible side-chain functionalities are suitably protected and the reactive amino group is tri-alkyl-silylated. n The new compounds of formula (VI) and a process for the preparation of a partially retro-inverso tuftsin analog which involves use of said method and said intermediate are also described and claimed.

专利号:US-9284343-B2
优先权日:2011-04-04
标 题:2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
发明人：BEAUCAGE SERGE L; CIESLAK JACEK
权利人:BEAUCAGE SERGE L; CIESLAK JACEK; US HEALTH
摘要:Disclosed are O-protected compounds of the formula (I): n nwherein B is an optionally protected nucleobase, and R 1 -R 3 are as described herein, wherein at least one of R 1 -R 3 is —CH 2 —O—Nâ•?CHR. The compounds are useful as intermediates in oligonucleotide synthesis. Also disclosed is a method of preparing the compounds from nucleosides via a process comprising conversion of a hydroxyl group to a methylthiomethoxy group, and a method of preparing oligonucleotides such as RNA starting from the compounds. The —CH 2 —O—Nâ•?CHR group is stable during oligonucleotide synthesis and can be easily removed after synthesis via, for example, treatment with a base.

专利号:WO-2010145821-A1
优先权日:2009-06-16
标 题 :Process for the synthesis of conjugates of glycosaminoglycanes (gag) with biologically active molecules, polymeric conjugates and relative uses thereof