CAS: 83-30-7; 2,4,6-Trihydroxybenzoic Acid

该化合物是一种酚色碳球酸,其特征是三个对称的羟基组,在苯环上分布在对称.这种结构具有很强的铬化和抗氧化性特性,使其在分析化学中有用,作为金属离子检测的根和中间有机合成.它在极地溶剂中的高溶性以及酸性条件下的稳定性增强了其在实验室环境中的可应用性.该化合物的苯丙基组还有助于它作为合成更复杂的芳香衍生物的前体发挥作用.其定义明确的分子结构和再活性特征使得它成为化学和材料科学协调研究的宝贵试剂.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

methyl iodide quercetin-3-O-β-L-rhamnopyranosyl-(1->6)-β-D-glucopyranoside quercetol 3,5-dihydroxyphenol methyl-2,6-dihydroxy-4-methoxybenzoate methyl 4,6-dimethoxysalicylate methyl 2,4,6-trimethoxybenzoate methyl 2,4,6-trihydroxybenzoate

合成工艺路线路线简述

  • 89-86-1 = 83-30-7
    反应条件:1.1 Reagents: Acetic Acid,Sulfuric Acid,Chromic Acid (H2Cr2O7),Compd. With Quinoline (1:2) Solvents: Water; Cooled; 323 K; 24 H,323 K
    标题:Kinetics Of The Oxidation Of Salicyclic Acids By Quinolinium Dichromate
    作者:Suante,H.; Et Al
    参考文献:Oxidation Communications 日期:2005 卷标:28(3) 页码:681-688]

    487-70-7 = 83-30-7
    反应条件:1.1 Reagents: Potassium Bromate,Potassium Bromide Catalysts: Hydrochloric Acid Solvents: Water; 12 H,Rt
    标题:Oxidation Of Aromatic Aldehydes With Potassium Bromate-Bromide Reagent And An Acidic Catalyst
    作者:Sharma,G. V. R.; Et Al
    参考文献:Research On Chemical Intermediates 日期:2013 卷标:39(7) 页码:3251-3254]

    65039-03-4 + 71-52-3 = 83-30-7
    反应条件:1.1 Solvents: 1H-Imidazolium,3-Ethyl-1-Methyl-,Carbonate (1:1); 104 S,10 Bar,135 °C
    标题:Intensified Kolbe-Schmitt Synthesis Using Continuous Microreactor Processing,Reactive Ionic Liquids And Microwave Heating
    作者:Krtschil,Ulrich; Et Al
    参考文献:Vdi-Berichte 日期:2008 卷标:2039 页码:117-124]

    99-96-7 = 83-30-7
    反应条件:1.1 Reagents: Acetic Acid,Sulfuric Acid,Chromic Acid (H2Cr2O7),Compd. With Quinoline (1:2) Solvents: Water; Cooled; 323 K; 24 H,323 K2.1 Reagents: Acetic Acid,Sulfuric Acid,Chromic Acid (H2Cr2O7),Compd. With Quinoline (1:2) Solvents: Water; Cooled; 323 K; 24 H,323 K
    标题:Kinetics Of The Oxidation Of Salicyclic Acids By Quinolinium Dichromate
    作者:Suante,H.; Et Al
    参考文献:Oxidation Communications 日期:2005 卷标:28(3) 页码:681-688]

    520-18-3 = 83-30-7 + 99-96-7
    反应条件:1.1 Reagents: Tetraethylammonium Bromide,Potassium Superoxide Solvents: Dimethylformamide; 15 Min,Rt1.2 15 H,Rt
    标题:Reactivity Pattern Of In Situ Generated Tetraethylammoniun Superoxide With Some Flavonoids
    作者:Singh,Krishna Nand; Et Al
    参考文献:Indian Journal Of Chemistry 日期:2007 卷标:(9) 页码:1554-1557]

    480-16-0 = 83-30-7 + 89-86-1
    反应条件:1.1 Reagents: Oxygen Catalysts: Manganese Oxide (Mno2); 25 °C
    标题:Isothermic Adsorption Of Morin Onto The Reducible Mesoporous Manganese Oxide Materials Surface
    作者:Ilunga,Ali K.; Et Al
    参考文献:Applied Catalysis 日期:2018 卷标:224 页码:928-939]

    153-18-4 = 83-30-7 [标题:Reaction Conditions
    标题:2,46-Trihydroxybenzoic Acid Manufacture By Corynebacterium
    参考文献:Japan]

    298-14-6 = 83-30-7
    反应条件:1.1 Reagents: Resorcinol Solvents: Water; 465 S,40 Bar,120 °C
    标题:Microreactor Processing For The Aqueous Kolbe-Schmitt Synthesis Of Hydroquinone And Phloroglucinol
    作者:Hessel,Volker; Et Al
    参考文献:Chemical Engineering & Technology 日期:2007 卷标:30(3) 页码:355-362]

    17575-26-7 = 83-30-7
    反应条件:1.1 Reagents: Oxygen
    标题:Sensitized Photooxygenation Of Coumarins
    作者:Chibber,S. S.; Et Al
    参考文献:Indian Journal Of Chemistry 日期:1979 卷标:(6) 页码:538-9]

    80432-08-2 + 71-52-3 = 83-30-7
    反应条件:1.1 Solvents: 1-Butyl-3-Methylimidazolium Hydrogen Carbonate; 104 S,10 Bar,135 °C
    标题:Intensified Kolbe-Schmitt Synthesis Using Continuous Microreactor Processing,Reactive Ionic Liquids And Microwave Heating
    作者:Krtschil,Ulrich; Et Al
    参考文献:Vdi-Berichte 日期:2008 卷标:2039 页码:117-124]

    = 83-30-7 + 65-85-0
    反应条件:1.1 Reagents: Tetraethylammonium Bromide,Potassium Superoxide Solvents: Dimethylformamide; 15 Min,Rt1.2 16.5 H,Rt
    标题:Reactivity Pattern Of In Situ Generated Tetraethylammoniun Superoxide With Some Flavonoids
    作者:Singh,Krishna Nand; Et Al
    参考文献:Indian Journal Of Chemistry 日期:2007 卷标:(9) 页码:1554-1557]

    117-39-5 = 83-30-7 + 99-50-3
    反应条件:1.1 Reagents: Tetraethylammonium Bromide,Potassium Superoxide Solvents: Dimethylformamide; 15 Min,Rt1.2 18 H,Rt
    标题:Reactivity Pattern Of In Situ Generated Tetraethylammoniun Superoxide With Some Flavonoids
    作者:Singh,Krishna Nand; Et Al
    参考文献:Indian Journal Of Chemistry 日期:2007 卷标:(9) 页码:1554-1557]

    480-16-0 = 83-30-7 + 89-86-1
    反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: [[4,4′,4′′,4′′′-[(29H,31H-Phthalocyanine-C,C,C,2-Tetrayl-Kn29,Kn30,Kn31,Kn32)Tet... Solvents: Water; 25 Min,Ph 10.5,25 °C
    标题:The Investigation Of Oxidative Bleaching Performance Of Peripherally Schiff Base Substituted Tri-Nuclear Cobalt-Phthalocyanine Complexes
    作者:Sen,Pinar; Et Al
    参考文献:Inorganica Chimica Acta 日期:2017 卷标:462 页码:30-39]

    480-16-0 = 83-30-7 + 294662-64-9 + 89-86-1
    反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: Cobalt Oxide (Co3O4),Lithium; 3 Min,Rt
    标题:Effect Of Alkali And Alkaline Earth Metal Dopants On Catalytic Activity Of Mesoporous Cobalt Oxide Evaluated Using A Model Reaction
    作者:Bingwa,Ndzondelelo; Et Al
    参考文献:Applied Catalysis 日期:2018 卷标:555 页码:189-195]

    117-39-5 = 83-30-7 + 99-50-3 + 10118-81-7 + 69098-01-7 + 30048-34-1 + 102788-23-8
    反应条件:1.1 Reagents: Potassium Hydroxide,Potassium Chloride,β-Cyclodextrin Solvents: Water
    标题:The Influence Of The Host-Guest Interaction On The Oxidation Of Natural Flavonoid Dyes
    作者:Ramesova,Sarka; Et Al
    参考文献:Collection Of Czechoslovak Chemical Communications 日期:2011 卷标:76(12) 页码:1651-1667
高良姜素置于potassium Superoxide,四乙基溴化铵体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 16.5H,以27%的收率获得产物2,4,6-三羟基苯甲酸
参考文献:Singh,Krishna Nand; Kumar,Rajesh,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,2007,Vol. 46,# 9,P. 1554-1557
标题:Singh,Krishna Nand; Kumar,Rajesh,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,2007,Vol. 46,# 9,P. 1554-1557

海关参考信息

专利信息


专利号:US-5386019-A
优先权日:1992-01-15
标 题 :Synthesis of inhibitors of calmodulin-mediated enzymes including KS-501, KS-502 and their enantiomers
发明人：DANISHEFSKY SAMUEL J; DUSHIN Russell; HAIT WILLIAM N
权利人:UNIV YALE
摘要:The total synthesis of a group of compounds with inhibitory effects on calmodulin-mediated enzyme activities has been accomplished. Among these synthesized compounds are KS-501 and KS-502. Other compounds that have been synthesized by the described scheme are ent-KS-501 and ent-KS-502 which are enantiomers of KS-501 and KS-502 and which also have inhibitory effects on calmodulin-mediated enzyme activities.

专利号:US-9611255-B2
优先权日:2015-06-10
标题 :Process for total synthesis of flavonoid compounds and isomers thereof
发明人：RAO BATCHU VENKATESWARA; LINGAMURTHY MACHA; RAJU Gurrapu; SARMA VANKA UMAMAHESWARA
权利人:COUNCIL SCIENT IND RES; COUNCIL SCIENT IND RES
摘要:The present invention relates to the a process for total synthesis of flavonoid compounds of general formula I and isomers thereof n nwherein R 1 and R 2 is OH; R 3 â•?H orn n n n n n n n n n n The present invention particularly relates to the process for preparation and separation of (2S,3S)-taxifolin-6-C-β-D-glucopyranoside (ulmoside A), (2R,3R)-taxifolin-6-C-β-D-glucopyranoside and taxifolin.

专利号:US-6180830-B1
优先权日:1995-11-08
标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes
发明人：JACQUOT ROLAND
权利人:RHODIA CHIMIE SA
摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.

专利号:US-4107210-A
优先权日:1976-09-07
标 题 :Synthesis of alpha-diketones
发明人：FREITER EDWARD R
权利人:DOW CHEMICAL CO
摘要:Alpha-diketones, such as 1-phenyl-1,2-propanedione and 1-propyl-1,2-butanedione, are prepared by reacting an acylmethyl ester of a carboxylic acid (e.g., benzoylmethyl acetate or butanoylmethyl propionate) with an aldehyde, such as formaldehyde or acetaldehyde, in the presence of an acid catalyst and water. Such alpha-diketones are also obtained by first refluxing a mixture of an alpha-haloketone and a carboxyl anion source and then reacting the mixture with an aldehyde in the presence of an acid catalyst and water.

专利号:US-10017391-B2
优先权日:2015-04-23
标题:Direct polymer templating synthesis of mesoporous carbon
发明人：DAI SHENG; NELSON KIMBERLY M
权利人:UT BATTELLE LLC; UNIV TENNESSEE RES FOUND
摘要:The invention is directed to a method for fabricating a mesoporous carbon composite material. The method comprises providing a precursor composition and subjecting the precursor material to a curing step followed by carbonization step. The precursor composition comprises (i) a templating component comprised of a linear homopolymer material, (ii) a phenolic compound or material, (iii) a crosslinkable aldehyde component, and (iv) an acid catalyst.

专利号:US-2025162973-A1
优先权日:2022-02-22
标题:Methods of synthesis and uses of agrimol compounds
发明人：CHE CHI MING; FU ZHIWEN; LEUNG YIU CHUNG GULICE
权利人:VERSITECH LTD; LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:Synthetic agrimol B and derivatives thereof (“compoundsâ€?) that have anticancer properties are disclosed. Methods for synthesizing the compounds with an overall yield ≥7% are disclosed. Pharmaceutical formulations in forms suitable for the delivery of the compounds to a subject in need thereof are disclosed. Methods of using the compounds for treating a cancer, reducing a cancer, or treating or ameliorating one or more symptoms associated with a cancer, such as non-small-cell lung cancer, in a subject are also disclosed. The methods include (i) administering to the subject the pharmaceutical formulation containing one or more compounds, for one or more times. The compounds can selectively kill cancer cells and/or cancer stem cells over noncancerous cells by inducing mitochondria dysfunction and/or inhibiting ER to Golgi trafficking in the cancer cells and/or cancer stem cells.

其他信息查阅

上海蓝润化学有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证，请用户仔细辨别，谨慎交易。
数据来源于公开网络搜索，平台未作核实，请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.longrunchem.com
企业联系电话：021-69515658;13701998368👤
📞上海蓝润化学有限公司 ⚠️参考联系方式
联系人：路小姐
电话：021-69515658;13701998368
手机：13701998368
传真：QQ:819185261
邮箱：longrunchem@163.com
通信地址: 上海市青浦区重固镇赵重公路2278号5号楼4层C区34座
邮编: 201800
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→

地址:上海市青浦区重固镇赵重公路2278号5号楼4层C区34座
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别
✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。
常州市金坛中兴医药化工有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证，请用户仔细辨别，谨慎交易。
数据来源于公开网络搜索，平台未作核实，请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.zxpharm.com
企业联系电话：0519-82850188;82850288👤
📞常州市金坛中兴医药化工有限公司 ⚠️参考联系方式
联系人：赵剑
电话：0519-82850188;82850288
手机：13901492272,13806141272
传真：0519-82850388
邮箱：webmaster@zxpharm.com
通信地址: 江苏省常州市金坛区金城镇后阳化工园区12号
邮编: 213200
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→

地址:江苏省常州市金坛区金城镇后阳化工园区12号
⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别
✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。
第 1 / 1 页

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis And Fate Of O-Carboxybenzophenones In The Biosynthesis Of Aflatoxin
作者:Kevin M. Henry,Craig A. Townsend |发布日期:2005.3.1
摘要:Oxidative Rearrangement Of Anthraquinone Natural Products To Xanthones In Vivo. Many Of These Baeyer-Villiger-Like Cleavages Are Believed To Be Carried Out By Cytochrome P450 Enzymes. In The Biosynthesis Of The Fungal Carcinogen, Aflatoxin, Six Cytochromes P450 Are Encoded By The Biosynthetic Gene Cluster. One Of These, Afln, Is Known To Be Involved In The Conversion Of The Anthraquinone Versicolorin A (3)

合成参考文献


摘要:Dembitsky, V. M.; Vil’, V. A., Science of Synthesis Knowledge Updates, (2019) 3, 360.
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
参考文献:10.1007/s10265-021-01325-0
摘要:Zhou S, Yang J, Qian C, Yin X, Yan X, Fan X, Fang T, Gao Y, Chang Y, Ma X. Organic acid metabolites involved in local adaptation to altitudinal gradient in Agriophyllum squarrosum, a desert medicinal plant. Journal of Plant Research. 2021 Jul 26;134(5):999–1011. doi: 10.1007/s10265-021-01325-0.
参考文献:10.1007/s00394-004-0502-2
摘要:Aura A-, Martin-Lopez P, O’Leary KA, Williamson G, Oksman-Caldentey K-, Poutanen K, Santos-Buelga C. In vitro metabolism of anthocyanins by human gut microflora. European Journal of Nutrition. 2004 Apr 28;44(3):133–42. doi: 10.1007/s00394-004-0502-2.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知