CAS: 108-03-2; 1-Nitropropane

上下游产品

CAS号74-98-6 丙烷 | CAS号3156-70-5 (E)-1-nitroprop... | CAS号107-08-4 1-碘丙烷 | CAS号106-94-5 溴代丙烷 | CAS号106-97-8 丁烷 | CAS号589-57-1 二乙基亚磷酰氯 | CAS号12384-98-4 aci-1-nitroprop... | CAS号75-52-5 硝基甲烷 | CAS号557-20-0 二乙基锌 | CAS号7697-37-2 硝酸 | CAS号105678-25-9 N-b°C-丙胺 | CAS号3431-62-7 3-硝基苯甲醛肟 | CAS号50766-86-4 3-硝基苯丁酮 | CAS号6270-16-2 3-硝基-2-丁醇,异构体混合物 | CAS号5447-99-4 3-硝基二戊醇 | CAS号4208-57-5 2-丁酰呋喃 | CAS号22632-02-6 2-bromo-2-nitro... | CAS号2108-81-8 (NE)-N-heptan-3...

丙烷置于硝酸,氯体系中,化学反应生成硝基丙烷
参考文献:Drug Therapy And Prevalence Of Erectile Dysfunction In The Massachusetts Male Aging Study Cohort
标题:Drug Therapy And Prevalence Of Erectile Dysfunction In The Massachusetts Male Aging Study Cohort
摘要:研究目标:检查常用药物与勃起功能障碍(ed)在两个时间点的关联. 设计:基于人群的横断面调查分析. 参与者:从马萨诸塞州男性衰老研究(mmas)中随机选取的男性队列,包括1476名男性作为基线(1987-1989年)和922名男性用于后续分析(1995-1997年). 干预:通过卡方统计分析特定药物类别之间的粗略关联.使用逻辑回归分析来区分药物效应与心脏病,高血压,未治疗糖尿病或抑郁症状的影响. 测量和主要结果:在mmas中,通过家庭访问访谈收集病史,当前药物使用情况和勃起功能状态.在未调整分析中,噻嗪类和非噻嗪类利尿剂,β-阻滞剂,钙通道阻滞剂,Angiotensin转化酶抑制剂,苯二氮平,洋地黄,硝酸盐,3-羟基-3-甲基谷氨酰辅酶a还原酶抑制剂和组胺h2受体拮抗剂与已存在的ed相关.调整合并症和健康行为后,这些关联减弱,仅非噻嗪类利尿剂和苯二氮平的统计显著性仍然存在. 结论:一些常用药物可能增加ed的发生率;然而,需要来自更大人群的额外数据,以确定这些关联是否独立于潜在健康状况,并探索剂量和使用持续时间的影响.
Doi:10.1592/phco.21.7.676.34571

专利信息

专利号:US-9988364-B1
优先权日:2017-03-21
标题 :Process for synthesis of Eliglustat and intermediate compounds thereof
发明人：LIU YU; YU GUANNENG; ZHENG ZHIGUO
权利人:ZHEJIANG AUSUN PHARMACEUTICAL CO LTD
摘要:The present invention relates to a process for synthesis of Eliglustat and intermediate compounds thereof. In particular, the present invention relates to a process for synthesis of Eliglustat and pharmaceutically acceptable salts thereof, and relates to the intermediate compounds in the process and a process for preparation of the intermediate compounds.

专利号:US-5442065-A
优先权日:1993-09-09
标 题:Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin
发明人：MAGNUS PHILIP D; ILIADIS THEODORE; EISENBEIS SHANE A; FAIRHURST ROBIN A
权利人:UNIV TEXAS
摘要:A process is described for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin. The synthesis allows efficient production of the enediyne as a stable, compound in good yield from the adamantyl N-protected azabicyclo[7.3.1]tridecadiyne. The adamantyl protecting group is employed in the starting material, N-adamantyl dihydroquinoline or N-adamantyl 6-methoxy quinoline. Also disclosed are process for the synthesis of 3-hydroxy-6-methoxyquinoline and several N-substituted derivatives of azobicyclo[7.3.1]tridecaenediyne. Solid tumor and leukemia assays were performed on the analogs of dynemicin. The results suggest a method that these compounds will useful in treating certain types of leukemias and solid tumors. The disclosed synthesis provides a route to new dynemicin intermediates and analogs which will allow development of second and third generation dynemicins.

专利号:US-4938940-A
优先权日:1988-01-14
标 题:Vapor-phase method for synthesis of diamond
发明人：HIROSE YOICHI; KOMAKI KUNIO
权利人:HIROSE YOICHI; SHOWA DENKO KK
摘要:A method for vapor-phase synthesis of diamond comprises burning a raw material compound for synthesis of diamond thereby forming a combustion flame, disposing a substrate for deposition of diamond in said combustion flame, and keeping said substrate at a prescribed temperature, thereby inducing deposition of diamond on said substrate.

专利号:US-4219489-A
优先权日:1978-09-05
标题:Synthesis of steroids
发明人：BUNES LEONARD A; JOHNSON WILLIAM S
权利人:STANFORD LELAND JUNIOR UNIV TR
摘要:Method and compounds are provided for use in the synthesis of steroids wherein a polyolefin is provided having an initiating group having a chalcogen atom in juxtaposition to a double bond, so as to be capable of bond formation to close to form a ring and having a terminating group involving pi unsaturation (a double or triple bond) conjugated to an aromatic ring. Upon acid catalysis, sigma bonds are formed through the interaction of a carbocation formed at the carbon atom bonded to the chalcogen atom and the double bond intermediate the initiating group and the terminating group, which close to form rings of a steroid nucleus, the carbocation interacting with the pi unsaturation conjugated with the aromatic group and being captured by a nucleophile present in the acidic reaction medium. The resulting steroid product may then be modified in known ways to produce known steroids.

专利号:US-12281398-B2
优先权日:2022-02-07
标题:Microfluidic process for the general electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds
发明人：SCHROER THORSTEN G; LECROY GREGORY E; AGUILA MIGUEL; RODRIGUEZ MAYRA P; DOWNARD TYLER J; MACLEOD BRIANNA L
权利人:US GOV AIR FORCE; US AIR FORCE
摘要:A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps ofpumping a solution comprising a compound of Formula Iinto a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator;applying an electrical current through the microfluidic electrochemical reactor; andperforming oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II

专利号:US-3884945-A
优先权日:1973-04-26
标题 :Synthesis of steroids by cyclization in nitro solvents
发明人：JOHNSON WILLIAM S; MORTON DOUGLAS R; GRAVESTOCK MICHAEL B
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Synthesis of steroids by cyclization of a dienyne cyclization substrate to a steroid or A-nor steroid employing a primary or secondary aliphatic nitro compound as solvent, thereby forming an oxime ether group at the C-17 position of the resulting steroid (or at the corresponding position of the resulting A-nor steroid where that is the product of cyclization). This oxime group can be converted to an hydroxy group by reductive cleavage. Conversion of the cyclization products to steroids such as 17hydroxypregnan-20-ones and testosterone is facilitated. The method is also applied to cyclization of suitable substrates to bicyclic products.