CAS: 141556-45-8; 1,3-Dimesityl-1H-Imidazol-3-Ium Chloride

上下游产品

N,N'-bis(2,4,6-trimethylphenyl)ethanediimine ethyl chloromethyl ether formaldehyd 1,N2-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine(E,E)-N1,N2-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine [1,3-bis(2,4,6-trimethylphenyl)imidazol]-2-ylidene 1,3-bis(2,4,6-trimethylphenyl)imidazolium-2-carboxylate H-imidazol-1-ium; chloride2-isobutoxycarbonyl-1,3-bis-(2,4,6-trimethyl-phenyl)-3H-imidazol-1-ium; chloride

2,4,6-三甲基苯胺置于盐酸,甲酸体系中,用 1,4-二氧六环,甲醇,水 用作溶剂,化学反应 27.0H,反应生成1,3-双(2,4,6-三甲基苯基)氯化咪唑
参考文献:A More Sustainable And Efficient Access To Imes.hcl And Ipr.hcl By Ball-Milling
标题:A More Sustainable And Efficient Access To Imes.hcl And Ipr.hcl By Ball-Milling
摘要:一种用户友好型且环保的合成方法,通过机械化学方法实现了广泛使用的n-杂环卡宾(nhc)前体的合成.
Doi:10.1039/c7Gc03539J

专利信息

专利号:WO-2025119975-A1
优先权日:2023-12-04
标 题:A method for synthesis of harmine
发明人：HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN
权利人:RECONNECT LABS AG
摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.

专利号:WO-2009135600-A1
优先权日:2008-05-07
标题:Catalysts for the synthesis of polyurethanes
发明人：LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.

专利号:US-8071783-B2
优先权日:2007-03-16
标题:N-heterocyclic carbene catalyzed synthesis of N-phenylisoxazolidin-5-one derivative and synthesis of β-amino acid ester derivative
发明人：ZHANG YUGEN; YING JACKIE Y; SEAYAD JAYASREE; PATRA PRANAB K
权利人:ZHANG YUGEN; YING JACKIE Y; SEAYAD JAYASREE; PATRA PRANAB K; AGENCY SCIENCE TECH & RES
摘要:A process for preparing a N-phenylisoxazolidin-5-one derivative is provided. The process for preparing the N-phenylisoxazolidin-5-one derivative comprises reacting an α,β-unsaturated aldehyde with nitrosobenzene in the presence of a N-heterocyclic carbene (NHC) catalyst. A process for preparing an N-alkoxyphenyl protected β-amino acid ester derivative is further provided. The process for preparing the N-alkoxyphenyl protected β-amino acid ester derivative comprises reacting an α,β-unsaturated aldehyde with nitrosobenzene in the presence of a N-heterocyclic carbene (NHC) catalyst to form a N-phenylisoxazolidin-5-one derivative, and then treating the N-phenylisoxazolidin-5-one derivative with an alcohol in the presence of an acid catalyst. A process for preparing an N-alkoxyphenyl protected β-amino acid ester derivative, comprising treating a N-phenylisoxazolidin-5-one derivative with an alcohol in the presence of an acid catalyst, is also provided.

专利号:US-7109348-B1
优先权日:2002-08-30
标题 :Synthesis of 1,3 distributed imidazolium salts
发明人：NOLAN STEVEN P
权利人:UNIV NEW ORLEANS RES AND TECHN
摘要:Imidazolium salts are the immediate precursors to N-heterocyclic carbenes (NHC) yet a simple, general synthetic route to a wide variety of imidazolium salts is not yet available. Such a straightforward route is described for two specific members of this family of ligand precursor: 1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride (IMes.HCl) and 1,3-Bis(2,6-diispropylphenyl)imidazolium chloride (IPr.HCl). The procedure appears general and similar protocols can be used to isolate various imidazolium salts.

专利号:US-10457640-B2
优先权日:2016-10-19
标 题:Synthesis of inhibitors of EZH2
发明人：VASWANI RISHI G; HEWITT MICHAEL CHARLES
权利人:CONSTELLATION PHARMACEUTICALS INC
摘要:Provided herein are synthetic methods for the preparation of EZH2 inhibitors.

专利号:US-2013131343-A1
优先权日:2009-12-07
标 题:Microwave-assisted synthesis of n-heterocyclic carbene transition metal complexes
发明人：NAVARRO OSCAR; WINKELMANN OLE H
权利人:NAVARRO OSCAR; WINKELMANN OLE H; UNIV HAWAII
摘要:Microwave heating is used to synthesize NHC-transition metal complexes. Reaction times for the formation of NHC-transition metal complexes is greatly reduced. The speed of the reactions allows for otherwise problematic air handling of reagents. Apparatus for carrying out the reactions is less complex than conventional apparatus and requires less energy to achieve the desired temperatures. Methods utilize salts of NHC's which overcomes the oftentimes difficult preparation of free carbenes for formation of the corresponding transition metal complexes.