CAS: 125401-75-4; 2,6-Bis((4,6-Dimethoxypyrimidin-2-yl)Oxy)Benzoic Acid

该化合物是一种选择性除草剂,主要用于控制大叶草和水稻种植中某些草草,它属于杀虫菊酯类和功能,抑制对植物中分链氨基酸合成至关重要的酶乙酸合成酶(ALS),这种行动机制导致蛋白合成的中断,最终导致植物死亡.双子菌的特点是它对哺乳动物和鸟类的毒性相对较低,因此在农业应用中是一种首选.它通常是在乳后施用,针对已经发芽的杂草.该化合物在有机溶剂中溶解,在环境中具有中度稳定,有可能通过微生物活动降解.它在许多国家得到管制,并且必须遵守建议的应用准则,以尽量减少对杂草人群的环境影响和抗药性发展.总的来说,双子菌是综合杂草管理战略中的有效工具,特别是在水稻生产系统中.

结构式图片

上下游产品

4,6-dimethoxypyrimidin-2-yl methyl sulfone 2,6-Dihydroxybenzoic acid methyl 2,6-dihydroxybenzoateisopropylidene aminoester of 2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid bispyribac sodium salt

合成工艺路线路线简述

  • 合成目标产物 Bispyribac 主要起始原料 2,6-Dihydroxybenzoic Acid And 2-Methanesulfonyl-4,6-Dimethoxypyrimidine
  • (文献来源)合成步骤主要原料 2,6-Dihydroxybenzoic Acid 和 2-Methanesulfonyl-4,6-Dimethoxypyrimidine
2,6-二羟基苯甲酸置于硫酸,Potassium Carbonate,柠檬酸体系中,用 丙酮 用作溶剂,化学反应生成双草醚
参考文献:一种双草醚衍生物及其制备方法与应用
标题:一种双草醚衍生物及其制备方法与应用
摘要:本发明公开了一种双草醚衍生物及其制备方法与应用,具有如下结构:具体制备步骤如下,2,6‑二羟基苯甲酸为原料,经多步反应合成双草醚(酸),后制备成双草醚酰氯,进一步与2‑吡啶基乙醇酯化反应合成双草醚衍生物2‑(吡啶‑2‑基)乙基‑2,6‑二((4,6‑二甲氧基吡啶‑2‑基)氧基)苯甲酸酯.本发明的化合物具有较好的除草活性,特别是对双子叶杂草播娘蒿有较好的防除活性,制备方法操作简单,收率较高.

海关参考信息

专利信息


专利号:WO-2024256370-A1
优先权日:2023-06-13
标 题 :Synthesis of glufosinate using an amidase-based process
发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

专利号:US-2025120400-A1
优先权日:2021-12-10
标题:Synthesis of glufosinate using a hydantoinase-based process
发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

专利号:WO-2021130756-A1
优先权日:2019-12-25
标题:Combinations of non-protein amino acids and acetolactate synthase enzyme inhibitors
发明人:KLIPCAN LIRON; VAN-OSS PINHASI RUTH
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:The present invention provides compositions and methods for disrupting protein synthesis in plant cells.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

专利号:US-9999223-B2
优先权日:2008-05-21
标 题 :Herbicidal composition comprising glyphosate, glufosinate or their salts
发明人:SIEVERNICH BERND; MOBERG WILLIAM KARL; SIMON ANJA; WALTER HELMUT; EVANS RICHARD R
权利人:BASF SE
摘要:The present invention relates to a herbicidal composition which comprises:n a) at least one herbicide A selected from glyphosate, glufosinate and their salts, and b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone]. nn The present invention relates in particular to a herbicidal composition comprising:n a) at least one herbicide A selected from glyphosate, glufosinate and their salts, b) a herbicide B which is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-oxazole [common name: pyroxasulfone], and c) at least one further herbicide C, which is selected from the herbicide groups C.1 to C.8:n C.1 herbicides of the group of acetolactate synthase inhibitors (ALS inhibitors), C.2 herbicides of the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors), C.3 herbicides of the group of auxines, C.4 herbicides of the group of 4-hydroxyphenyl-pyruvate-dioxygenase inhibitors (HPPD inhibitors), C.5 herbicides of the group of phytoene desaturase inhibitors (PDS inhibitors), C.6 herbicides of the group of photosystem II inhibitors (PSII inhibitors), C.7 herbicides of the group of microtubulin inhibitors, and C.8 herbicides of the group of inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors).
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合成参考文献


参考文献:10.1007/s00894-011-1169-2
摘要:Singh DV, Adeppa K, Misra K. Mechanism of isoproturon resistance in Phalaris minor: in silico design, synthesis and testing of some novel herbicides for regaining sensitivity. Journal of Molecular Modeling. 2011 Jul 15;18(4):1431–45. doi: 10.1007/s00894-011-1169-2.
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