CAS: 464-06-2; 2,2,3-Trimethylbutane

该化合物是一种含有分子式C8H18的分链烷,其特点是结构结构,具有中丁烷主干骨,与第二和第三个碳原子相连.这种配置有助于其高度的分流,影响其物理和化学特性.该物质在室温下是一种无色液体,与类似分子重量的直链烷相比,其沸点相对较低,使其更加挥发性.2,2,3-三甲基丁烷以其高辛烷等级而著称,这使其在汽油配制,提高燃料性能和减少发动机撞击中成为有价值的成分.它也相对稳定且不具有极性,在标准条件下表现出低的再活动性.此外,该物质在水中不溶解,但在有机溶剂中溶解,碳氢化合物是典型的.安全考虑因素包括其易燃性以及吸入或皮肤接触时可能对健康造成影响,需要采取适当的处理和储存措施.

结构式图片

欧盟法规

统一分类与标签压力设备指令-第1组危险流体REACH注册ECHA物质欧盟气雾剂指令-标签制度ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号594-83-2 五甲基乙醇 | CAS号67-56-1 甲醇 | CAS号79-29-8 2,3-二甲基丁烷 | CAS号142-82-5 正庚烷 | CAS号55505-23-2 2,2,3-trimethyl... | CAS号187737-37-7 propene | CAS号75-28-5 异丁烷 | CAS号78-78-4 异戊烷 | CAS号115-10-6 二甲醚 | CAS号564-02-3 2,2,3-三甲基戊烷 | CAS号591-76-4 2-甲基已烷(异庚烷) | CAS号565-59-3 2,3-二甲基戊烷 | CAS号589-34-4 3-甲基己烷 | CAS号142-82-5 正庚烷 | CAS号513-35-9 2-甲基-2-丁烯 | CAS号187737-37-7 propene | CAS号74-84-0 乙烷 | CAS号74-98-6 丙烷 | CAS号563-78-0 2,3-二甲基-1-丁烯 | CAS号115-11-7 2-甲基丙烯

合成工艺路线路线简述

  • 合成目标产物 2,2,3-Trimethylbutane 主要起始原料 Methanol And 2,3-Dimethylbutane
  • (文献来源)合成步骤主要原料 Methanol 和 2,3-Dimethylbutane
2,2,3-三甲基戊烷置于kieselguhr,氢气,镍体系中,化学反应生成 2,2,3-三甲基丁烷
参考文献:Haensel; Ipatieff,Journal Of The American Chemical Society,1946,Vol. 68,P. 346
标题:Haensel; Ipatieff,Journal Of The American Chemical Society,1946,Vol. 68,P. 346

专利信息


专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人:WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:WO-2013065009-A1
优先权日:2011-11-01
标题:A sortase-click reaction suite for synthesis of multivalent dendrimeric protein assembly
发明人:GUPTA KANCHAN; SINGH SHIKHA; KHAN NAEEM; SEHGAL DEVINDER; ROY RAJENDRA PRASAD
权利人:NAT INST IMMUNOLOGY
摘要:The present invention relates to synthesis of bio-conjugates and well-defined multivalent protein dendrimer assembly by a general and straightforward chemo- enzymatic method. The method involves a simple two-step process in which proteins appended with an orthogonal label by facile sortase-mediated ligation are conjugated to a multivalent dendritic scaffold using the versatile copper-catalyzed azide-alkyne cycloaddition reaction. The 'Sortase-Click' strategy produces satisfactory yield of dendrimers under mild conditions from readily available His6 -tagged proteins and serves as a powerful general strategy for covalent assembly of bio-conjugates and protein dendrimers.

专利号:US-7504524-B2
优先权日:2004-07-26
标题:Method for synthesis of 2,5-dioxane-1,4-diones
发明人:BOURISSOU DIDIER; MARTIN-VACA BLANCA; BEN FREDERIC; GRAULLIER MAGALIE; CHERIF-CHEIKH ROLAND; MONTES MARTIN
权利人:SOD CONSEILS RECH APPLIC
摘要:The invention relates to a novel method for the synthesis of 2,5-dioxane-1,4-diones having formula (I), comprising the oxidation of the ketone function of a cyclic compound having formula (II), wherein R 1 , R 2 , R 3 and R 4 independently represent the hydrogen atom, halo, (C 2 -C 6 ) alkenyl, (C 3 -C 7 )cycloalkyl, cyclohexenyl and a radical having formula —(CH 2 ) m —V—W.

专利号:WO-2015183067-A1
优先权日:2014-05-30
标题 :Synthesis of analogues of y-amino acids and resulting products
发明人:FERNÃ?NDEZ ZERTUCHE MARIO; TOVAR GUDIÑO ERIKA; TRUJILLO FERRARA JOSÉ GUADALUPE; GUEVARA SALAZAR JUAN ALBERTO
权利人:UNIV AUTÓNOMA DEL ESTADO DE MORELOS
摘要:The invention relates to a compound of formula (see formula), suitable for use as drugs in the treatment of chronic neurodegenerative disorders of the Huntington's disease, Parkinson's disease and epilepsy type, inter alia . The invention relates to novel methods for the synthesis of said analogues and the pharmaceutically acceptable solvates and salts thereof.

专利号:US-8889926-B2
优先权日:2011-06-30
标 题:Method for the synthesis of low cost initiators for telechelic polyisobutylenes
发明人:KENNEDY JOSEPH P; ERDODI GABOR
权利人:KENNEDY JOSEPH P; ERDODI GABOR; UNIV AKRON
摘要:A method for the synthesis of 1,3-di(chloropropyl)-5-tert-butyl benzene includes the steps of conducting Friedl-Crafts alkylation of 1,3-diisopropyl benzene by tert-butyl chloride in the presence of an alkylation catalyst to obtain 1-tert-butyl-3,5-diisopropylbenzene; peroxidizing the 1-tert-butyl-3,5-diisopropyl benzene by gaseous oxygen in the presence of a peroxidation catalyst in a basic solution to obtain 1,3-di(peroxypropyl)-5-tert-butylbenzene; reducing the 1,3-di(peroxypropyl)-5-tert-butylbenzene with a reducing agent to 1,3-di(hydroxylpropyl)-5-tert-butylbenzene; and chlorinating the 1,3-di(hydroxypropyl)-5-tert-butylbenzene to obtain 1,3-di(chloropropyl)-5-tert-butyl benzene.

专利号:WO-2005103035-A1
优先权日:2004-04-23
标题:Modified fischer indole synthesis of eletriptan
发明人:ASHCROFT CHRISTOPHER PAUL
权利人:PFIZER LTD; ASHCROFT CHRISTOPHER PAUL; PFIZER
摘要:The present invention relates to a new process for the preparation of eletriptan (I), or its enantiomer comprising a modified Fischer indole synthesis, namely the reaction of a compound of formula (II), wherein R1 is a suitable hydrazine protecting group, with a compound of formula (III) wherein R2 is an aldehyde group (-CHO) or the functional equivalent thereof.
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合成参考文献


参考文献:10.2165/11590370-000000000-00000
摘要:Källén B, Nilsson E, Otterblad Olausson P. Delivery outcome after maternal use of drugs for migraine: a register study in Sweden. Drug Saf. 2011 Aug 01;34(8):691–703. doi: 10.2165/11590370-000000000-00000.
参考文献:10.1007/s10194-011-0364-y
摘要:Gaul C, Visscher CM, Bhola R, Sorbi MJ, Galli F, Rasmussen AV, Jensen R. Team players against headache: multidisciplinary treatment of primary headaches and medication overuse headache. The Journal of Headache and Pain. 2011 Jul 21;12(5):511–9. doi: 10.1007/s10194-011-0364-y.
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