CAS: 1459-96-7; Dimethyl Bicyclo[2.2.2]Octane-1,4-Dicarboxylate

相似化合物

711-02-4 18720-35-9 94994-15-7

上下游产品

1-(2-氯乙基)环己烷-1,4-二羧酸二甲酯 Dimethyl 1-(2'-Chloroethyl)Cyclohexane-1,4-Dicarboxylate 106004-06-2
二环[2,2,2]辛烷-1,4-环己二羧酸 1,4-Bicyclo[2.2.2]Octanedicarboxylic Acid 711-02-4
1,4-环己烷二羧酸二甲酯 Dimethyl 1,4-Cyclohexane Dicarboxylate 94-60-0
1,4-立方烷二甲酸二甲酯 Cubane-1,4-Dicarboxylic Acid Dimethyl Ester 29412-62-2
1,4-环己烷二甲酸 Cyclohexane-1,4-Dicarboxylic Acid 1076-97-7
2,5-二氧代双环[2.2.2]辛烷-1,4-二羧酸二甲酯 Dimethyl 2,5-Dioxobicyclo[2,2,2]Octane-1,4-Dicarboxylate 57293-62-6
Dimethyl Bicyclo[2.2.2]Oct-2-Ene-1,4-Dicarboxylate 1659-67-2

1,4-环己烷二甲酸置于六甲基磷酰三胺,正丁基锂,氯化亚砜,二异丙胺体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 1.0H,反应生成双环[2.2.2]辛烷-1,4-二羧酸二甲酯
参考文献: Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines,Compositions Thereof,And Methods Of Treatment Therewith[fr] Diaminocarboxamidepyrimidines Et Diaminocarbonitrilepyrimidines Substituées,Compositions De Celles-Ci Et Procédés De Traitement à L'Aide De Celles-Ci
标题: Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines,Compositions Thereof,And Methods Of Treatment Therewith[fr] Diaminocarboxamidepyrimidines Et Diaminocarbonitrilepyrimidines Substituées,Compositions De Celles-Ci Et Procédés De Traitement à L'Aide De Celles-Ci
摘要:本文提供具有以下结构的二氨基嘧啶化合物:其中r1,R2,R3和r4如本文所定义,包含有效量二氨基嘧啶化合物的组合物,以及用于治疗或预防肝纤维化疾病或通过抑制jnk途径可治疗或预防的疾病的方法.

专利信息

专利号:US-11518726-B2
优先权日:2017-10-11
标题 :Synthesis of bicyclo[2.2.2]octane derivatives
发明人：HU YUE RACHEL; HEMBRE ROBERT THOMAS; TUSTIN GERALD CHARLES; LIU ZHUFANG; ADAMS STEVEN J
权利人:EASTMAN CHEM CO
摘要:Provided is a process for the preparation of certain 1,4-bicyclo[2.2.2]octane derivatives. The new synthetic procedure involves treating 1,4-dimethylene cyclohexane with an oxidizing agent in the presence of a transition metal catalyst to afford an oxo-substituted bicyclo[2.2.2]octane species. This intermediate structure can then be further derivatized. The processes of this disclosure thus affords a novel and simplified means for the commercial production of a wide variety of bicyclo[2.2.2]octane derivatives.

专利号:EP-3694831-A1
优先权日:2017-10-11
标题:Synthesis of bicyclo[2.2.2]octane derivatives

专利号:WO-2019075004-A1
优先权日:2017-10-11
标 题:SYNTHESIS OF BICYCLO [2.2.2] OCTANE DERIVATIVES

专利号:CN-111433181-A
优先权日:2017-10-11
标题 :Synthesis of Bicyclo[2.2.2]octane Derivatives

专利号:US-2020270191-A1
优先权日:2017-10-11
标 题 :Synthesis of bicyclo[2.2.2]octane derivatives

专利号:CN-111433181-B
优先权日:2017-10-11
标题:Synthesis of Bicyclo[2.2.2]octane Derivatives