CAS: 3149-28-8; 2-Methoxypyrazine

相似化合物

4774-15-6 38028-67-0 68468-30-4

上下游产品

CAS号14508-49-7 2-氯吡嗪 | CAS号124-41-4 甲醇钠 | CAS号865-33-8 甲醇钾 | CAS号6542-37-6 (四氢-1H-恶唑并[3,4-... | CAS号23902-69-4 Pyrazine, 2-met... | CAS号32046-05-2 2-methoxypyrazi... | CAS号23902-69-4 Pyrazine, 2-met... | CAS号2847-30-5 2-甲氧基-3-甲基吡嗪 | CAS号58139-04-1 2-碘-3-甲氧基吡嗪 | CAS号4774-10-1 2-氨基-3-甲氧基吡嗪 | CAS号138430-98-5 3-(3-methoxypyr... | CAS号56343-40-9 1-(3-methoxypyr... | CAS号63874-90-8 2-甲酰基-3-甲氧基吡嗪

2-氯吡嗪,Sodium Methylate 以 甲醇 用作溶剂,化学反应 2.0H,以92%的收率获得2-甲氧基吡嗪
参考文献:A New Route To Aminodiazines Via Metalation Reaction. Synthesis Of An Aza Analogue Of Nevirapine: Diazines Xv
标题:A New Route To Aminodiazines Via Metalation Reaction. Synthesis Of An Aza Analogue Of Nevirapine: Diazines Xv
摘要:报道了一种合成氨基二嗪的新路线,使用了二嗪的邻位定向锂化,随后与作为电亲体的托烯基叠氮化物反应.对所获得的叠氮或四唑化合物进行了还原,得到了预期的胺.这种方法学使得新氨基二嗪的合成成为可能,并提高了之前描述的各种氨基二嗪的收率.该反应被用于制备 Nevirapine 的氮杂类似物.
Doi:10.1055/s-1996-4303

专利信息

专利号:US-2025034146-A1
优先权日:2023-07-13
标题:Electro-photochemical synthesis of 1,2,4-triazolo-[4,3-a]pyrazine
发明人：PIERCEY DAVIN GLENN; YOUNT JOSEPH ROBERT
权利人:PURDUE RESEARCH FOUNDATION
摘要:A method of preparing a 1,2,4-triazolo-[4,3-a]pyrazine backbone using an electro-photochemical process comprising coupling a compound comprising a 5-substituted tetrazole moiety to a compound comprising an optionally substituted pyrazine moiety electrochemically and subjecting the resulting compound to photochemical excitation with ultraviolet light.

专利号:WO-2013112823-A1
优先权日:2012-01-25
标题 :Heterophase synthesis of metal-coordinated framework materials for particle size control
发明人：AHN DONGCHAN; LEE JEONG YONG
权利人:DOW CORNING
摘要:Various embodiments of the present invention relate to a method of preparing coordination polymer crystals, and to the crystals produced thereby. The method includes providing a composition. The composition includes Component (i), a metal-containing compound that is a source of one or more metal ions; Component (ii), a bridging ligand-containing compound that is a source of one or more bridging ligands; Component (iii), a first liquid in which (i) and (ii) are soluble; and Component (iv), a second liquid immiscible with the first liquid. The method includes mixing the composition to form an emulsion. The method also includes maintaining the emulsion for a time sufficient to produce a crystalline coordination polymer. Various embodiments also provide methods of making membranes and membranes made thereby wherein the membrane-forming composition includes the coordination polymer crystals, including methods of making membranes wherein coordination polymer crystals form in the membrane or in the membrane-forming composition before, during, or after curing of the membrane-forming composition. Various embodiments also provide methods of gas separation using the membranes.

专利号:US-2024335442-A1
优先权日:2021-08-02
标 题:N-acylhydrazone compounds capable of inhibiting nav1.7 and/or nav1.8, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人：BARREIRO GABRIELA; SANT'ANA DANILO PEREIRA DE; GAMBA LUIS EDUARDO REINA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA; LIMA LÃ?DIA MOREIRA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO UFRJ
摘要:N-acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein the substituents R1 to R6 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of said compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, and which are applicable in the fields of medicinal chemistry and organic synthesis, as well as in the treatment of pain-related disorders.

专利号:US-6103865-A
优先权日:1998-08-03
标 题 :PH-sensitive polymer containing sulfonamide and its synthesis method
发明人：BAE YOU HAN; PARK SANG YEOB
权利人:KWANGJU INST SCI & TECH
摘要:There are disclosed pH-sensitive polymers containing sulfonamide groups, which can be changed in physical properties, such as swellability and solubility, depending on pH and which can be applied for a drug-delivery system, bio-material, sensor, etc, and a preparation method therefor. The pH-sensitive polymers are prepared by introduction of sulfonamide groups, various in pKa, to hydrophilic groups of polymers either through coupling to the hydrophilic groups, such as acrylamide, N,N-dimethylacrylamide, acrylic acid, N-isopropylacrylamide, etc, of polymers or copolymerization with other polymerizable monomers. These pH-sensitive polymers may have a structure of linear polymer, grafted copolymer, hydrogel or interpenetrating network polymer.

专利号:US-10000598-B2
优先权日:2012-10-15
标题:Methods for preparation of molecularly imprinted polymers for wine extraction
发明人：BELBRUNO JOSEPH J
权利人:DARTMOUTH COLLEGE
摘要:Disclosed herein are compositions of, synthesis methods and methods of use for improved molecularly imprinted polymers useful for extracting target molecule compounds of wine.

专利号:US-6552018-B1
优先权日:1997-01-27
标 题:Pyrazole derivatives
发明人：EJIMA AKIO; OHSUKI SATORU; OHKI HITOSHI; NAITO HIROYUKI
权利人:DAIICHI SEIYAKU CO
摘要:The present invention relates to cis- and trans-forms of pyrazole derivatives, salts thereof, or agents containing the same, and represented by the general formula (I): n wherein G represents a nitrogen containing saturated heterocyclic structure represented by the following formula: n These compounds exhibit anti-tumor activity on 5-FU-resistant tumors and effects on P glycoprotein expressing, multiple-drug resistant tumors. An example of a pyrazole derivative which demonstrates 50% inhibition of tumor cell growth is 3-[4-(3-chloro-5-fluorophenyl)- 1 piperazinyl]-1-[1-(3-chloro-2-pyridyl)-5-methyl-4-pyrazolyl)-1-trans-propene hydrochloride. Synthesis of the compounds represented by formula (I) can be prepared by any one of various routes such as a Mannich reaction, a Wittig reaction, reductive amination or substitution by allylation.