CAS: 33184-16-6; 5-Fluoro-2-Methylbenzoic Acid

上下游产品

CAS号124-38-9 二氧化碳 | CAS号246877-31-6 3-Amino-5-fluor... | CAS号1006-34-4 2-溴-5-氟苯甲酰胺 | CAS号1082040-43-4 6-氟-1H-吲哚-4-甲酸甲酯 | CAS号33184-52-0 5-fluoro-2-meth... | CAS号138786-65-9 2-(溴甲基)-5-氟苯甲酸甲酯 | CAS号175278-29-2 5-氟-2-甲基苯甲酸甲酯 | CAS号1207453-91-5 4-氨基-6-氟异苯并呋喃-1... | CAS号1207453-90-4 6-氟-4-硝基异苯并呋喃-1... | CAS号697739-03-0 2-甲基-3-硝基-5-氟苯甲酸甲酯 | CAS号850462-64-5 5-氟-2-甲基-3-硝基苯甲酸

5-氟-2-甲基苯甲醇置于potassium Hydroxide体系中,用 水 作为反应溶剂,110.0 °C,1.0 Mpa 条件下,反应 24.0H,以91%的收率获得产物5-氟-2-甲基苯甲酸
参考文献:用于有氧氧化合成(杂)芳香醛,酮,酯,酸,腈和酰胺的"通用"催化剂
标题:用于有氧氧化合成(杂)芳香醛,酮,酯,酸,腈和酰胺的"通用"催化剂
摘要:功能化(杂)芳族化合物是基础和应用科学中广泛使用的不可或缺的化学品.其中,尤其是芳香醛,酮,羧酸,酯,腈和酰胺是有价值的精细和大宗化学品,可用于化学,制药,农业化学和材料工业.对于它们的合成,醇的催化有氧氧化构成了一种绿色,可持续且具有成本效益的工艺,理想情况下应该利用活性和选择性的 3D 金属.在这里,我们报告了通过在碳上热解钴-哌嗪-酒石酸络合物作为最通用的氧化催化剂,制备包裹在 Co-纳米颗粒中的石墨层.这种独特的材料可以合成简单,功能化和结构多样的(杂)芳香醛,酮,
DOI:10.1016/j.Chempr.2021.12.001

专利信息

专利号:WO-0010565-A1
优先权日:1998-08-18
标 题 :Growth hormone secretagogues
发明人：DODGE JEFFREY ALAN; HAUSER KENNETH LEE; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR CHARLES WILLIS III; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROBERT LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
权利人:LILLY CO ELI; DODGE JEFFREY ALAN; HAUSER KENNETH LEE; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR CHARLES WILLIS III; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROBERT LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:EP-3515880-B1
优先权日:2017-03-17
标题:Methods and compositions for synthesis of encoded libraries
发明人：LI JIN; MORGAN BARRY A; Wan jinqiao; DOU DENGFENG; LIU GUANSAI; CHANG YONG; CHEN QIUXIA; WANG XING; XU YANSHAN; HU DONGYAN; LIU JIAN; CHENG XUEMIN
权利人:HITGEN INC

专利号:US-2020149034-A1
优先权日:2017-03-17
标题:Methods and Compositions for Synthesis of Encoded Libraries

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-6992097-B2
优先权日:1998-08-18
标 题 :Growth hormone secretagogues
发明人：HAUSER KENNETH LEE; DODGE JEFFREY ALAN; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR III CHARLES WILLIS; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROGER LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
权利人:LILLY CO ELI
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:CN-116813508-A
优先权日:2022-03-21
标 题 :Method for highly selective synthesis of 5-halo-2-methylbenzoic acid