CAS: 6100-74-9; 3'-Hydroxy-4'-Methoxyacetophenone

上下游产品

CAS号88114-44-7 1-(4-methoxy-3-... | CAS号1197-09-7 3,4-二羟基苯乙酮 | CAS号74-88-4 碘甲烷 | CAS号1131-62-0 3,4-二甲氧基苯乙酮 | CAS号613-70-7 邻甲氧基苯乙酸酯 | CAS号621-59-0 异香兰素； 3-羟基-4-甲氧... | CAS号108-24-7 乙酸酐 | CAS号91-16-7 1,2-二甲氧基苯 | CAS号75-36-5 乙酰氯 | CAS号23428-77-5 1-(3-(苄氧基)-4-甲氧... | CAS号2785-88-8 5-乙基-2-甲氧基苯酚 | CAS号520-34-3 香叶木素 | CAS号31526-71-3 1-(3-乙氧基-4-甲氧基苯基)乙酮 | CAS号88114-44-7 1-(4-methoxy-3-... | CAS号881919-82-0 BENZENE, 2-ETHO... | CAS号918137-24-3 (5-acetyl-2-met... | CAS号918137-27-6 2-methoxy-5-(6-...

对甲氧基苯乙酮置于c28H46N4O10S2,双氧水,溶剂黄146,Iron(II) Chloride体系中,用 水,乙腈 作为反应溶剂,化学反应 1.0H,以65%的收率获得产物4-甲氧基-3-羟基苯乙酮
参考文献:铁催化芳烃c-H羟基化
标题:铁催化芳烃c-H羟基化
摘要:由于芳基碳氢键的相对惰性,酚类产物的较高反应性导致过度氧化的副产物以及经常不足的区域选择性,芳烃的可持续,非定向和选择性催化羟基化仍然是一项持续的研究挑战.我们报告说,铁由受生物启发的l-胱氨酸衍生的配体可以催化非定向芳烃碳氢羟基化,过氧化氢作为末端氧化剂.该反应以其广泛的底物范围,出色的选择性和非常好的产率而著称,并且表现出与氧化敏感官能团的相容性,如醇,多酚,醛,甚至硼酸.该方法非常适合通过多重碳氢羟基化合成多酚,以及天然产物和药物分子的后期功能化.
DOI:10.1126/science.Abj0731

专利信息

专利号:US-9321804-B2
优先权日:2011-03-09
标题 :Synthesis and use of anti-tumor drug LQC-Y
发明人：LEI HAIMIN
权利人:UNIV BEIJING CHINESE MEDICINE; 3D MEDICINES LTD
摘要:Disclosed are the general structural formula of LQC-Y as well as the synthesis and use thereof. Pharmacological experiments demonstrated the marked antitumor effect of such compounds. Single day administration of LQC-Y3 to mice at a maximum dose of 6000 mg/kg showed no toxicity response during the 14-day continuous observation period, indicating the high safety of the compounds, and the compounds can be used to prepare medicaments for preventing and treating carcinomas such as liver cancer, lung cancer. In the general structural formula of LQC-Y, R represents steroid compounds such as cholic acid, deoxycholic acid, ursodeoxycholic acid, chenodeoxycholic acid, and hyodeoxycholic acid and so on; triterpenoid compounds such as oleanolic acid, ursolic acid, pachymic acid, glycyrrhetinic acid and glycosides thereof and so on; emodic acid, emodin and other mono-substituted or poly-substituted structures of anthraquinone parent nucleus; baicalein, baicalin and other flavonoid; shikimic acid, mono-substituted shikimic acid or poly-substituted shikimic acid; gardenia acid and other iridoid acid derivatives; paeonol, curcumin and structural derivatives thereof.

专利号:US-12024521-B2
优先权日:2020-06-30
标 题:Isoquinoline derivatives, methods of synthesis and uses thereof
发明人：Paulvannan Kumarapandian; SOLAS DENNIS; KITAYGORODSKYY ANATOLIY; LINGAPPA VISHWANATH R
权利人:PROSETTA BIOSCIENCES INC
摘要:Described herein are compounds, pharmaceutical compositions and methods of using these compounds and pharmaceutical compositions for treating and/or preventing conditions such as amyotrophic lateral sclerosis. These compounds and pharmaceutical compositions are also useful as antivirals and antimicrobial agents.

专利号:US-9018203-B2
优先权日:2012-04-18
标题 :Pharmaceutical composition of salicylanilide-derived small molecules and preparation and application thereof
发明人：CHANG DEH-MING; HUANG HSU-SHAN; CHEN CHUN-LIANG; LEE CHIA-CHUNG
权利人:CHANG DEH-MING; HUANG HSU-SHAN; CHEN CHUN-LIANG; LEE CHIA-CHUNG; NAT DEFENSE MEDICAL CT
摘要:The present invention provides a pharmaceutical composition of salicylanilide-derived small molecules include:n (a) a compound which structure is selected from formula I or formula II: nn n n n n n n n n n n n (b) a pharmaceutically acceptable salt and excipient. The present invention also provides the synthesis method of the pharmaceutical composition and the application thereof.

专利号:CN-1337391-A
优先权日:2001-08-17
标题 :A New Process for the Phosgene Synthesis of a Class of Medicinal Acetylsalicylate Derivatives

专利号:US-2024300962-A1
优先权日:2020-06-30
标题 :Isoquinoline Derivatives, Methods of Synthesis and Uses Thereof

专利号:US-2014011786-A1
优先权日:2011-03-09
标题:Synthesis and use of anti-tumor drug lqc-y