CAS: 818-08-6; Dibutyl(Oxo)Tin

上下游产品

CAS号71-36-3 正丁醇 | CAS号1002-53-5 二丁基锡烷 | CAS号56-35-9 三丁基氧化锡 | CAS号7067-44-9 butyltricyclohe... | CAS号1118-46-3 丁基三氯化锡 | CAS号78-94-4 丁烯酮 | CAS号106-51-4 苯醌 | CAS号589-92-4 4-甲基环己酮 | CAS号98-53-3 4-叔丁基环己酮 | CAS号119-61-9 二苯甲酮 | CAS号5926-85-2 1,3-dimethoxy-1... | CAS号1067-55-6 二丁基二甲氧基锡 | CAS号1066-68-8 dibutyltin,trib... | CAS号104697-81-6 [dibutyl-[2-(2-... | CAS号34833-46-0 butoxy-[butoxy(... | CAS号3349-36-8 二丁氧基二丁基锡烷 | CAS号563-25-7 二丁基二氟锡 | CAS号17997-43-2 Dibutylbis(phen... | CAS号2050-95-5 diisopentyl car... | CAS号20556-88-1 [(4-aminobenzoy...

二丁基二氯化锡置于sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应生成 二正丁基氧化锡
参考文献:一种二丁基氧化锡的制备方法
标题:一种二丁基氧化锡的制备方法
摘要:一种二丁基氧化锡的制备方法.本发明属于超细粉体催化剂制备技术领域,具体涉及一种二丁基氧化锡的制备方法.具体包括以下步骤:(1)将二丁基二氯化锡加热至一定温度进行液化后导入雾化器中;(2)启动雾化器使液态二丁基二氯化锡雾化;(3)将雾化后的二丁基二氯化锡气流喷入装有碱液的反应釜中,充分混合后进行第一次反应;(4)反应完毕后将液体分离再加入碱液进行第二,三次反应;(5)水洗,离心,真空干燥,放料称重得到所需二丁基氧化锡产品.此方法合成的二丁基氧化锡细腻均匀,产品纯度高,可作为电泳漆催化剂使用.

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-7420052-B2
优先权日:2001-08-24
标 题:Intermediates for synthesis of vinblastine, process for preparation of the intermediates and process for synthesis of vinblastines
发明人：FUKUYAMA TOHRU; TOKUYAMA HIDETOSHI; YOKOSHIMA SATOSHI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:An intermediate for vinblastine synthesis represented by general formula A. n ngeneral formula A.n n(in the formula, R 1 , R 2 , R 3 and R 4 are the group selected independently from the group consisting of H, lower alkyl group, lower alkoxy group, halogen, lower perfluoroalkyl group, lower alkylthio group, hydroxy group, amino group, mono- or di-alkyl or acylamino group, lower alkyl or arylsulfonyloxy group. R 5 is H, or a lower alkyl group or a substituted or non-substituted aryl group, R 6 is an alkyl group of carbon number 4 or less, R 7 is a substituted or non-substituted aryl group, R 8 is a substituted or non-substituted aryl group or lower alkyl group and R 9 is an acyl group or trialkylsilyl group.) A method for synthesis of the compound of general formula A utilizing radical ring forming reaction of thioanilides and using the compound of general formula B as the starting material, synthesizing thioanilide of general formula C by the reaction with compound 1 and the formation of a 11-membered ring by intramolecular alkylation of 2-nitrobenzenesulfonamide by which the reactions can proceed under mild conditions and high yield can be accomplished.

专利号:US-11479577-B2
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY; DAVIES IEUAN; OTTER CARL; BATCHELOR RHYS
权利人:NZP UK LTD
摘要:The present invention relates to compounds which are intermediates in the synthesis of bile acid derivatives with pharmacological activity. The invention relates to compounds of general formula (I):wherein:, R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease. In addition, the invention relates to a method of synthesizing these intermediates and a method of preparing obeticholic acid and obeticholic acid analogues from the compounds of the invention.

专利号:US-2004018598-A1
优先权日:2000-05-30
标题 :Bio-intermediates for use in the chemical synthesis of polyketides
发明人：SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKS†) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediates†) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.

专利号:US-9233943-B2
优先权日:2012-01-10
标题:Process for synthesis of syn azido epdxide and its use as intermediate for the synthesis of amprenavir and saquinavir
发明人：GADAKH SUNITA KHANDERAO; REKULA REDDY SANTHOSH; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:A novel synthetic route to the syn-azido epoxide of formula 5 includes cobalt-catalyzed hydrolytic kinetic resolution of a racemic mixture of the azido-epoxide. Reaction steps include subjecting an allylic alcohol to epoxidation with mCPBA to obtain a racemic epoxy alcohol; ring opening the epoxy alcohol with azide anion to obtain an anti-azido alcohol, which can then be selectively tosylated at the primary alcohol; treating the tosylate with base to obtain the racemic azido-epoxide; and subjecting the racemic azido-epoxide to cobalt-catalyzed hydrolytic kinetic resolution to obtain the syn-azido epoxide of formula 5. The compound of formula 5 may be used as a common intermediate for the asymmetric synthesis of HIV protease inhibitors, such as Amprenavir, Fosamprenavir, Saquinavir, and formal synthesis of Darunavir and Palinavir.

专利号:US-5104498-A
优先权日:1988-01-08
标题 :Electrolytic synthesis of metal salts of weak acids
发明人：PEGOURET JEAN
权利人:SAINT GOBAIN RECH
摘要:The invention relates to the synthesis of metal salts of weak acids and in particular indium formate. n It proposes a process in which the anodic oxidation of metal is achieved under the effect of electric current in a cell filled with an electrolytic solution containing weak acid whose salt it is desired to produce, having at least its anode or anodes consisting of metal whose salt it is desired to produce. The salt is available in suspension in the electrolytic solution. n The invention also proposes an electrosynthesis cell, as well as products synthesized in a particular morphology. n The invention applies itself to the synthesis of indium formate in particular to pyrolyze it as a thin layer on glass.