CAS: 882499-87-8; Methyl 2-Amino-5-Bromo-4-Pyridinecarboxylate

相似化合物

1227586-36-8 1260664-14-9 1000339-23-0

上下游产品

methyl 2-aminoisonicotinatemethyl 2-aminoisonicotinate ethyl 6'-{[(ethylamino)carbonyl]amino}-4'-(4-phenyl-1,3-thiazol-2-yl)-3,3'-bipyridine-5-carboxylate N-[5-bromo-4-(4-phenyl-1,3-thiazol-2-yl)pyridin-2-yl]-N'-ethylurea 6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-ylboronic acid

2-氨基异烟酸甲酯置于溴体系中,用 氯仿 作为反应溶剂,以23%的收率获得产物2-氨基-5-溴异烟酸甲酯
参考文献:Bisaryl-Sulfonamides
标题:Bisaryl-Sulfonamides
摘要:提供了在治疗或预防由pparγ或pparδ介导的疾病或紊乱方面有用的化合物,组合物和方法.具体来说,本发明的化合物调节pparγ或pparδ的功能.该方法特别适用于治疗和/或预防糖尿病,肥胖症,高胆固醇血症,类风湿性关节炎和动脉粥样硬化.

专利信息

专利号:US-11319326-B2
优先权日:2015-03-30
标 题 :Tricyclic fused derivatives of 1-(cyclo)alkyl pyrtdin-2-one useful for the treatment of cancer
发明人：VADIVELU SARAVANAN; RAJAGOPAL SRIDHARAN; CHINNAPATTU MURUGAN; GONDRALA PAVAN KUMAR; SIVANANDHAN DHANALAKSHMI; MULAKALA CHANDRIKA
权利人:JUBILANT BIOSYS LTD
摘要:The present disclosure described heterocyclic compounds of Formula I or, its stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms and pharmaceutically active derivative thereof and pharmaceutical compositions containing them as the active ingredient. The present disclosure also describes the synthesis and characterization of aforementioned compounds to exhibit high anticancer activity. The compounds of the present disclosure are useful as medicaments and their use in the manufacture of medicaments for treatment, prevention or suppression of diseases, and conditions mediated by one or more BET family of bromodomains.