CAS: 351-50-8; H-D-His-Oh

相似化合物

109425-51-6 123333-71-1 135610-90-1

上下游产品

CAS号71-00-1 L-组氨酸 | CAS号75983-68-5 (R)-2-乙酰氨基-3-(1... | CAS号10101-30-1 N-乙酰基-DL-组织氨基酸 | CAS号1499-46-3 methyl (2S)-2-a... | CAS号4998-57-6 DL-组氨酸 | CAS号6893-26-1 D-谷氨酸 | CAS号2504-83-8 3-(4-咪唑)-2-氧丙酸

L-组氨酸 反应生成 D-组氨酸
参考文献:Biosynthesis Of A Broad-Spectrum Nicotianamine-Like Metallophore In Staphylococcus Aureus
标题:Biosynthesis Of A Broad-Spectrum Nicotianamine-Like Metallophore In Staphylococcus Aureus
摘要:所有细胞都必须找到一种获取微量金属的方法.例如,细菌和植物通过合成和释放称为铁载体的铁螯合化合物来清除铁.ghssein等人描述了金属载体的另一种类型的生物合成过程,该过程由金黄色葡萄球菌中的三种酶负责(见nolan的透视文章).代谢组学和一系列生化测定表明,该化合物名为staphylopine,根据生长环境的不同,参与吸收一系列金属.staphylopine生物合成所需的基因在许多致病细菌中保守,并且与植物产生的广谱金属载体的基因类似. Science,本期 P. 1105;另见p. 1055
DOI:10.1126/science.Aaf1018

专利信息

专利号:US-12421534-B2
优先权日:2021-11-10
标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
发明人：ALMHJELL PATRICK J; ARNOLD FRANCES H
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

专利号:WO-2023030277-A1
优先权日:2021-08-30
标 题:Method for fully liquid-phase synthesis of grnh nonapeptide amide analog
发明人：SUN PENGCHENG; PAN JING; WU JUNYONG; TANG YONGBO; Du Yixiong; GUO LIN
权利人:HUNAN MICRO PEPTIDE BIOMEDICAL CO LTD
摘要:Provided is a method for fully liquid-phase synthesis of a GRnH nonapeptide amide analog, which belongs to the technical field of medicine synthesis. The method comprises respectively synthesizing a 'Trp-Ser-Tyr' fragment, an 'R-Leu' fragment, a 'Pyr-His' fragment and 'Arg-Pro-Hunan T', wherein, R = D-Ala (alarelin), D-Leu (leuprorelin), D-Trp (deslorelin) and D-His (histrelin), and obtaining the GRnH nonapeptide amide analog with high yield and high purity by means of a '3 +2 +2 +2' fragment condensation method. The synthesis method is environmentally friendly, mild, and free of any highly toxic and poisonable reagents. The cost is greatly reduced and the synthesis method is very suitable for large-scale production.

专利号:EP-0443532-B1
优先权日:1990-02-20
标题:Temporary minimal protection synthesis of LH-RH analogs
发明人：NESTOR JOHN J JR; MCCLURE NATALIE L
权利人:SYNTEX INC
摘要:A solid phase synthesis of LH-RH analogs in which the amino acids serine and histidine, if present, are side chain protected during the synthesis with groups labile to selected alpha -amino or deprotecting agents.

专利号:US-2025042860-A1
优先权日:2022-04-22
标题:Process for Chemical Synthesis of Ergothioneine and Methods of Use
发明人：ZHU YONGXIAO; YU DONGDONG; ZHU YING; ZHU XI; LIAO KYLIN
权利人:NANJING NUTRABUILDING BIO TECH CO LTD
摘要:The present invention provides a process for chemical synthesis of different optical forms of ergothioneine (e.g., L-form or D-form or any mixture thereof). Another aspect of the invention relates to a composition comprising a non-racemic mixture of L-ergothioneine and D-ergothioneine.

专利号:US-8835477-B2
优先权日:2009-10-06
标题 :Method for the synthesis of 2-thiohistidine and the like
发明人：ERDELMEIER IRÈNE; DAUNAY SYLVAIN
权利人:ERDELMEIER IRÈNE; DAUNAY SYLVAIN; TETRAHEDRON
摘要:Methods for the synthesis of 2-thiohistidine or a derivative thereof of the formula (I), or of a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, from a compound of the formula (II) or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, by cleavage reaction in the presence of a thiol at a temperature higher than or equal to 60° C. The invention also relates to compounds of the formula (II) and a method for the synthesis thereof.

专利号:US-2019177392-A1
优先权日:2014-09-23
标 题 :Synthesis of glp-1 peptides
发明人：PENIAS NAVON SHARON; NAVEH SHIRLY; VASILEIOU ZOI; BARLOS KONSTANTINOS
权利人:NOVETIDE LTD
摘要:Disclosed are processes for the synthesis of GLP-1 peptides, such as liraglutide and semaglutide, and a process for purifying liraglutide.