CAS: 57497-39-9; N-(Tert-Butyl) Hydroxylamine Hydrochloride

相似化合物

16649-50-6 50632-53-6 10017-37-5

上下游产品

N-t-butylethylaminetert-butyl-3-methylamino-4-phenyl-2H-isoxazol-5-one2-tert-butyl-3-methylamino-4-phenyl-2H-isoxazol-5-one N-tert.-Butyl-N,O-bis-(phenylcarbamoyl)-hydroxylamin dibenzyl P-(N-tert-butyl-hydroxyaminomethyl)phosphonate 1-tert-Butyl-1-hydroxy-2-phenylisourea hydr°Chloride

N-叔丁基乙胺置于双氧水,盐酸体系中,用 甲醇,水 作为反应溶剂,40.0~60.0 °C,15.0 Kpa 条件下,反应 10.5H,反应生成 N-叔丁基羟胺盐酸盐
参考文献: Process For The Purification Of A Mixture Comprising N-Alkyl-Hydroxylammonium Salts[fr] Procédé De Purification D'Un Mélange Comprenant Des Sels De N-Alkyl-Hydroxylammonium
标题: Process For The Purification Of A Mixture Comprising N-Alkyl-Hydroxylammonium Salts[fr] Procédé De Purification D'Un Mélange Comprenant Des Sels De N-Alkyl-Hydroxylammonium
摘要:本发明涉及一种纯化包含水,N-烷基-羟胺盐和一些副产物的混合物的方法,其中从混合物中蒸馏出水和副产物,直到残渣中n-烷基-羟胺盐的纯度达到95%或更高,并在蒸馏过程中和之后保持水含量>=40重量百分比.

专利信息

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-11904268-B2
优先权日:2017-07-28
标题 :Preparation of new aldehyde and/or ketone traps and filters
发明人：TRAN-THI THU-HOA; BORTA ANA; GINEYS MICKAEL; SOM MARIE-PIERRE; HAMMEL FRÉDÉRIC
权利人:COMMISSARIAT ENERGIE ATOMIQUE; CENTRE NATIONAL DE LA RECH SCIENTIFIQUE—CNRS—
摘要:A method for preparing a nanoporous silica sol-gel matrix containing at least one amine reactant selected from hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, tetraethylenepentamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof, said method including the following steps: a) synthesising a gel from tetramethoxysilane or from a mixture of tetramethoxysilane and another organosilicon precursor selected from among phenyltrimethoxysilane, phenyltriethoxysilane, a fluoroalkyltrimethoxysilane, a fluoroalkyltriethoxysilane, a chloroalkylmethoxysilane, a chloroalkylethoxysilane, an alkyltrimethoxysilane, an alkyltriethoxysilane, an aminopropyltriethoxysilane and the mixtures thereof, the synthesis being performed in an aqueous medium at a temperature ranging from 10 to 70° C. in the presence of at least one amine reactant selected from among hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof; b) drying the gel obtained during step a) so as to obtain a sol-gel matrix containing at least one amine reactant.

专利号:AU-2020409711-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins

专利号:US-6512143-B1
优先权日:1998-07-10
标 题:Salts of N-tert-butylhydroxylamine
发明人：BLIXT JOERGEN
权利人:ASTRAZENECA AB
摘要:Novel salts of N-tert-butylhydroxylamine with lower carboxylic acids are disclosed, together with processes for their preparation. The salts possess advantageous properties that render them useful in synthesis.

专利号:EP-4076533-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins

专利号:CA-3164962-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins