专利号:CN-112961030-A 优先权日:2021-02-03 标 题:A kind of method for catalytic synthesis of 4-(trans-4-alkylcyclohexyl)cyclohexanone
专利号:US-9839664-B2 优先权日:2014-07-25 标 题 :GLP-1 receptor modulators 发明人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM R; BRAHMACHARY ENUGURTHI; FOWLER THOMAS; NOVAK ANDREW; MEGHANI PREMJI; KNAGGS MICHAEL 权利人:CELGENE INT II SÀRL 摘要:Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36), GLP-1(9-36), and oxyntomodulin, or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “ â€? represents either or both the R and S form of the compound): n nwhere A, B, C, R 1 , R 2 , R 3 , R 4 , R 5 , n, p and q are as defined herein.
专利号:CN-107501059-B 优先权日:2017-08-14 标 题:Green and environment-friendly synthesis method of 4- (4' -alkylcyclohexyl) cyclohexanone
专利号:CN-117326905-A 优先权日:2023-09-28 标 题:Synthesis method of (trans, trans)-4-ethyl-4’-propyl-1,1’-bicyclohexane
参考文献:10.1007/bf02253164 摘要:Kryvenko LI, Soldatova SA, Zvolinskii OV, Romanenko ÉÉ, Struchkova MI, Soldatenkov AT. Synthesis, structure, and biological activity of [2.2]paracyclophanes. 7. Synthesis of 2-([2.2]paracyclophan-4-yl)pyridines,-tetrahydroquinolines, and-benzo[h]quinolines based on condensation of 4-(β-dimethylaminopropionyl)[2.2]paracyclophane with primary amines. Chemistry of Heterocyclic Compounds. 1997 Aug;33(8):933–6. doi: 10.1007/bf02253164.