CAS: 929-59-9; 1,2-Bis(2-Aminoethoxy)Ethane

• 英文名称1,2-Bis(2-Aminoethoxy)Ethane
• 中文名称1,8-二氨基-3,6-二氧杂辛烷
• IUPAC名称2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-amine)
• 其它别名Bis-Nh2-Peg2; 3,6-Dioxaoctamethylenediamine; Edj; 1,8-Diaminotriethyleneglycol; H2N-Peg-Nh2; 2,2'-(Ethylenedioxy)Bis(Ethylamine), ; 1,2-Bis(2-Aminoethoxy)Ethane; 1,2-Bis-(2-Aminoe
• CAS编号929-59-9
• MFCD编号:MFCD00040474
• EINECS号:213-203-6
• FDA UNII编号:R41ZT4UF34
• 分子式:C6H16N2O2
• 分子量:148.2
• 产品CID: 1968430
• 产品分类有机原料→分子砌块→脂肪链类化合物

• 相似结构搜索
• 产品信息参考;
• InChIKey: IWBOPFCKHIJFMS-UHFFFAOYSA-N
• InChI=1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2…
• 计算化学: 氢键受体数4.0氢键供体数2.0可旋转键数7.0

相似化合物

物理性质

• 沸点105-109 °C at 6 mmHg
• 闪点110°C
• 密度1.015 g/mL at 25 °C(文献)
• pKa:9.04±0.10(预测)
• PSA:70.5
• LogP:-1.063
• 折射率n 20/D 1.461(文献)
• 蒸汽压71Pa at 20°C
• 溶解性Soluble In Dimethylformamide, Methanol
• 敏感性吸潮
• 外观形态无色至几乎无色液体
• 储存条件存储低于 +30°C.
• 产品应用该化合物用于连接器,形成含锰的硫化锌纳米粒子与叶酸的结合体.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07 & GHS05;
  注释: Exclamation mark & Corrosion
• 危险类别急性毒性 类别4(经口)
  皮肤腐蚀 类别1C
  严重眼损伤 类别1
  皮肤致敏 类别1B
  皮肤腐蚀 类别1B
  呼吸道致敏 类别1
  皮肤致敏 类别1
  特定目标器官毒性 - 单次接触 类别3
  水生慢性毒性 类别3
• 警示词Danger(危险)
• 危险描述H302 |吞咽有害.
  H314 |造成严重皮肤灼伤和眼损伤.
  H318 |造成严重眼损伤.
  H317 |可能引起皮肤过敏反应.
  H334 |吸入可能引起过敏或哮喘症状或呼吸困难.
  H335 |可能引起呼吸道刺激.
  H412 |对水生生物有害并具有长期持续影响.
• 防范说明P260-P261-P264-P270-P272-P280-P284-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
• 危险等级8
• UN编号2735.0
• 危险品标志C
• 包装等级Ⅱ
• 安全声明23-26-36/37/39-45
• 危险类别码22-34-42/43-37
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 1,8-Diamino-3,6-Dioxaoctane 主要起始原料 Triethylene Glycol Dimethanesulfonate
• 59086-77-0 = 929-59-9
  反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol; Rt
  标题:Method For Preparing Tert-Butyl 2-(2-(2-Aminoethoxy)Ethoxy)Ethyl Carbamate
  参考文献:China]
  
  929-59-9 = 929-59-9
  反应条件:1.1 Reagents: Potassium Cyanide,Nickel Dichloride,Silver Nitrate Solvents: Water; 2 Min,Rt1.2 Rt; 2 - 3 H,Rt
  标题:New Bimetallic Dicyanidoargentate(I)-Based Coordination Compounds: Synthesis,Characterization,Biological Activities And Dna-Bsa Binding Affinities
  作者:Korkmaz,Nesrin; Aydin,Ali; Karadag,Ahmet; Yanar,Yusuf; Maasoglu,Yelis; Et Al
  参考文献:Spectrochimica Acta 日期:2017 卷标:173 页码:1007-1022]
  
  112-27-6 = 929-59-9
  反应条件:1.1 Reagents: Ammonia Catalysts: Zinc Oxide (Zno),Alumina,Nickel Solvents: Water; 5 Mpa,185 °C
  标题:Preparation Of 1,8-Diamino-3,6-Dioxaoctane By Hydroamination Of Triethylene Glycol
  参考文献:China]
  
  112-27-6 = 929-59-9
  反应条件:1.1 Reagents: Hydrogen,Ammonia
  标题:Process For Synthesis Of A Mixture Of N,N,N',N'-Tetramethyl-1,6-Hexanediamine And N,N,N',N'-Tetramethyldiamino Ethers
  参考文献:France]
  
  7440-44-0 + 929-59-9 = 929-59-9
  反应条件:1.1 Reagents: Sulfuric Acid,Nitric Acid; 5 Min; 3 H,80 °C1.2 Reagents: Thionyl Chloride Solvents: Tetrahydrofuran; 24 H,80 °C1.3 Reagents: Pyridine Solvents: Dimethyl Sulfoxide; 12 H,Cooled
  标题:Surface Chemistry Dependent "Switch" Regulates The Trafficking And Therapeutic Performance Of Drug-Loaded Carbon Nanotubes
  作者:Das,Manasmita; Singh,Raman Preet; Datir,Satyajit R.; Jain,Sanyog
  参考文献:Bioconjugate Chemistry 日期:2013 卷标:24(4) 页码:626-639]
  
  929-59-9 = 929-59-9
  反应条件:1.1 Reagents: 1-Ethyl-3-(3′-Dimethylaminopropyl)Carbodiimide,1-Hydroxybenzotriazole,2-Propenoic Acid,1,1-Dimethylethyl Ester,Polymer With 1-(Chloromethyl)-4-Ethen... Solvents: Dimethylformamide; 1 H,Rt1.2 Reagents: Diisopropylethylamine Solvents: Dimethylformamide; 20 H,Rt1.3 Solvents: Dimethylformamide,Water; 1 H,Rt; 3 H,Rt; 12 H,Rt1.4 Reagents: Sodium Azide Solvents: Dimethyl Sulfoxide,Water; 24 H,Rt
  标题:64Cu Core-Labeled Nanoparticles With High Specific Activity Via Metal-Free Click Chemistry
  作者:Zeng,Dexing; Lee,Nam S.; Liu,Yongjian; Zhou,Dong; Dence,Carmen S.; Et Al
  参考文献:Acs Nano 日期:2012 卷标:6(6) 页码:5209-5219]
  
  79-06-1 + 929-59-9 = 929-59-9
  反应条件:1.1 Solvents: Water; 15 Min,80 °C
  标题:Supramolecular Complexing Of Membrane Siglec Cd22 Mediated By A Polyvalent Heterobifunctional Ligand That Templates On Igm
  作者:Cui,Lina; Kitov,Pavel I.; Completo,Gladys C.; Paulson,James C.; Bundle,David R.
  参考文献:Bioconjugate Chemistry 日期:2011 卷标:22(4) 页码:546-550]
  
  3386-87-6 = 929-59-9
  反应条件:1.1 Reagents: Potassium Methoxide,Hydrogen Catalysts: Octanedinitrile,Oft 60 Solvents: Methanol
  标题:Preparation Of Aliphatic Primary Amines By Hydrogenation Of Nitriles
  参考文献:Japan]
  
  59559-06-7 = 929-59-9
  反应条件:1.1 Reagents: Lithium Aluminum Hydride
  标题:Synthesis And Characterization Of Some Bifunctional 2B:2:1 Cryptands
  作者:Gansow,Otto A.; Kausar,A. Rashid; Triplett,Kelly B.
  参考文献:Journal Of Heterocyclic Chemistry 日期:1981 卷标:18(2) 页码:297-302]
  
  21442-01-3 + 100424-71-3 + 929-59-9 = 929-59-9
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Dimethylformamide,Water; 15 Min,Ph 9.01,0 °C; 15 Min,0 °C; 0 °C -> Rt; 2 H,Rt
  标题:Metap2 Inhibitors And Methods Of Treating Obesity
  参考文献:World Intellectual Property Organization]
  
  112-26-5 = 929-59-9
  反应条件:1.1 Reagents: Sodium Azide
  标题:Doubly And Triply Bridged Polyoxapolyazaheterophanes Derived From 2,4,6-Trichloro-S-Triazine
  作者:Anelli,Pier Lucio; Lunazzi,Ludovico; Montanari,Fernando; Quici,Silvio
  参考文献:Journal Of Organic Chemistry 日期:1984 卷标:49(22) 页码:4197-203]
  
  109-85-3 = 929-59-9
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran
  标题:Syntheses And Binding Properties Of Bibrachial Lariat Ethers (Bibles): Survey Of Synthetic Methods And Cation Selectivities
  作者:Gatto,Vincent J.; Arnold,Kristin A.; Viscariello,Anthony M.; Miller,Steven R.; Morgan,Charles R.; Et Al
  参考文献:Journal Of Organic Chemistry 日期:1986 卷标:51(26) 页码:5373-84]
  
  112-26-5 = 929-59-9
  反应条件:1.1 Reagents: Sodium Azide Solvents: Water; 15 H,98 °C1.2 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 0 °C; 16 H,Reflux1.3 Reagents: Sodium Hydroxide Solvents: Water; 12 H,Rt
  标题:A Novel Graphite-Like Stacking Structure In A Discrete Molecule And Its Molecular Recognition Behavior
  作者:Akine,Shigehisa; Onuma,Takahiro; Nabeshima,Tatsuya
  参考文献:New Journal Of Chemistry 日期:2018 卷标:42(12) 页码:9369-9372]
  
  31255-11-5 = 929-59-9
  反应条件:1.1 Reagents: Hydrazine Hydrate (1:1) Solvents: Ethanol; 2 H,Reflux1.2 Reagents: Hydrochloric Acid Solvents: Water; 1 H,Reflux; Reflux -> Rt1.3 Reagents: Sodium Hydroxide Solvents: Water; Neutralized,Rt
  标题:Study On Synthesis Of 1,8-Diamino-3,6-Dioxaoctane
  作者:Chen,Jianliang
  参考文献:Guangdong Huagong 日期:2015 卷标:42(17) 页码:221-222]
  
  31255-11-5 = 929-59-9 [标题:Reaction Conditions
  标题:Reaction Of N,N'-Substituted Derivatives Of Diphthalimide With Amines
  作者:Anikin,V. F.; Ganin,E. V.; Rozynov,B. V.; Zakharova,R. M.; Kamalov,G. L.
  参考文献:Khimiya Geterotsiklicheskikh Soedinenii 日期:1982 卷标:(2) 页码:246-9]
  
  19249-03-7 = 929-59-9
  反应条件:1.1 Reagents: Ammonium Hydroxide Solvents: 1,4-Dioxane,Water1.2 Reagents: Potassium Hydroxide Solvents: 1,4-Dioxane,Water
  标题:Proton-Ionizable Crown Compounds. 10. Preparation And Structural Studies Of Macrocyclic Ligands Containing Two Sulfonamide Units And With Seventeen To Twenty-Six Ring Members
  作者:Bradshaw,Jerald S.; Koyama,Hiroyuki; Dalley,N. Kent; Izatt,Reed M.; Biernat,Jan F.; Et Al
  参考文献:Journal Of Heterocyclic Chemistry 日期:1987 卷标:24(4) 页码:1077-83]
  
  929-59-9 = 929-59-9
  反应条件:1.1 Reagents: Triethylamine,Dicyclohexylcarbodiimide,Graphene (Oxide) Solvents: Dimethylacetamide; 48 H,Rt
  标题:An Extremely Productive And Sustainable Procedure For The Synthesis Of 2,4,5-Trisubstituted Imidazoles Using Graphene Oxide-Substituted Sulfoacetic Acid Amide
  作者:Zadeh,M. M. A.; Rostami,E.; Farhadi,A.
  参考文献:Russian Journal Of Organic Chemistry 日期:2022 卷标:58(10) 页码:1487-1497]
  
  59559-06-7 = 929-59-9
  反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol; 3 - 4 H,Rt
  标题:Modification Of Exenatide As Glp-1 Receptor Agonist For Treatment And Prevention Of Glycometabolism Related Disease
  参考文献:China

海关参考信息

• 2905310000-1,2-乙二醇
  2909110000-乙醚
  2922110001-单乙醇胺
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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