合成目标产物 N,N'-Dimethylpiperazine 主要起始原料 Piperazine And Formaldehyde
(文献来源)合成步骤主要原料 Piperazine 和 Formaldehyde
甘氨酸酐置于甲醇,镍体系中,200.0 °C,15.2 Mpa 条件下,反应生成1,4-二甲基哌嗪 参考文献:Ovakimian Et Al.,Journal Of Biological Chemistry,1940,Vol. 134,P. 155 标题:Ovakimian Et Al.,Journal Of Biological Chemistry,1940,Vol. 134,P. 155
专利号:US-2004242897-A1 优先权日:2002-07-31 标题 :Universal support media for synthesis of oligomeric compounds 发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH 摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.
专利号:US-6540970-B1 优先权日:1999-11-18 标题:Method for the synthesis of molecular sieves 发明人:STROHMAIER KARL G; VAUGHAN DAVID E W 权利人:EXXON MOBIL CHEM PATENTS INC 摘要:The present invention provides a method for the synthesis of MeAPO molecular sieves which includes the following steps: providing a source of alumina, a source of phosphorus, water, and a template suitable for forming a MeAPO molecular sieve; providing a source of metal (Me) including metal particles, the metal particles measuring, in their largest dimension, equal to or less than five nanometers; providing a water soluble organic solvent capable of solubilizing the source of metal; forming a synthesis mixture from the source of alumina, the source of phosphorus, the water, the template, the source of metal, and the solvent; and forming a MeAPO molecular sieve from the synthesis mixture.
专利号:US-8309740-B2 优先权日:2008-05-13 标题 :One-pot synthesis of fluorinated ionic liquids 发明人:LEE HYUN JOO; SUH DONG JIN; AHN BYOUNG SUNG; KIM HONG GON; KIM CHANG SOO; KIM HOON SIK 权利人:LEE HYUN JOO; SUH DONG JIN; AHN BYOUNG SUNG; KIM HONG GON; KIM CHANG SOO; KIM HOON SIK; KOREA INST SCI & TECH 摘要:The present invention relates to a method for one-pot synthesis of ionic liquid with fluoroalkyl group, more particularly to a method for one-pot synthesis of ionic liquid with fluoroalkyl group represented by the following Chemical Formula 1 by adding and reacting a nitrogen-containing compound, a Brønsted acid of the formula YH and a fluoroolefin compound of the formula CFR 1 â•?CR 2 R 3 in a single reactor: n n n n n n n n n n wherein n nrepresents a nitrogen-containing compound; Y − represents an anion of the Brønsted acid; and R 1 , R 2 and R 3 , which may be same or different, represent hydrogen, fluorine, C 1 -C 10 alkyl or C 1 -C 10 fluoroalkyl having from 1 to 23 fluorine atoms.
专利号:US-8138346-B2 优先权日:2006-08-16 标题 :Method for synthesis of 8-alkoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones 发明人:BRADBURY BARTON JAMES; WILES JASON ALLAN; HASHIMOTO AKIHIRO; WANG QIUPING; LUCIEN EDLAINE; PAIS GODWIN; KIM HA YOUNG 权利人:BRADBURY BARTON JAMES; WILES JASON ALLAN; HASHIMOTO AKIHIRO; WANG QIUPING; LUCIEN EDLAINE; PAIS GODWIN; KIM HA YOUNG; ACHILLION PHARMACEUTICALS INC 摘要:The present invention provides process for synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones of the Formula A. n nThe substituents R, R 5 , R 6 , R 7 , R 8 and R 9 are defined herein. The invention also provides novel synthetic intermediates useful in the synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones.
专利号:US-5145957-A 优先权日:1988-03-18 标 题:Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4-aroyloxy azetidinone 发明人:TSCHAEN DAVID M; LYNCH JOSEPH E; LASWELL WILLIAM L; VOLANTE RALPH P; SHINKAI ICHIRO 权利人:MERCK & CO INC 摘要:A process is described for the stereocontrolled synthesis of (3R,4R)-3-[(1R)-1-hydroxyethyl]-4-benzoyloxyazetidin-2-ones and their derivatives by cycloaddition involving an imine and a ketone, generated from 3(S)-hydroxybutyrate which are useful intermediates in the synthesis of carbapenem antibiotics.
专利号:EP-0269236-B1 优先权日:1986-10-24 标题:Process for synthesis of a chiral azetidinone 摘要:A process is described for the stereo-controlled synthesis of 3-(R)-3-[1'-(R)-hydroxyethyl]-4-(R)-benzoyl-2-oxo-1-aze tidines and their derivatives which are useful intermediates in the synthesis of carbapenem antibiotics.