CAS: 17890-56-1; Benzo[b]Thiophen-2-Ylmethanol

上下游产品

CAS号17890-55-0 苯并[b]噻吩-2-羧酸乙酯 | CAS号3541-37-5 苯并[b]噻吩-2-甲醛 | CAS号50-00-0 甲醛 | CAS号95-15-8 苯并噻吩 | CAS号6314-28-9 苯并噻吩-2-羧酸 | CAS号108-23-6 氯甲酸异丙酯 | CAS号22913-24-2 甲基苯并噻吩-2-甲醛 | CAS号2076-88-2 2-(氯甲基)苯并[b]噻吩 | CAS号151-50-8 氰化钾 | CAS号446-52-6 邻氟苯甲醛 | CAS号3541-37-5 苯并[b]噻吩-2-甲醛 | CAS号6314-28-9 苯并噻吩-2-羧酸 | CAS号197245-31-1 N-BSM°C-L-天冬酰氨酸 | CAS号197245-21-9 N-Bsm°C-L-亮氨酸 | CAS号2076-88-2 2-(氯甲基)苯并[b]噻吩 | CAS号197245-19-5 N-BSM°C-L-苯基丙胺酸 | CAS号197245-22-0 N-BSM°C-L-异亮氨酸 | CAS号197245-27-5 N-BSM°C-L-色氨酸 | CAS号197245-15-1 N-BSM°C-L-丙氨酸 | CAS号197245-29-7 N-BSM°C-L-蛋氨酸

1-苯并噻酚-2-羧醛置于sodium Tetrahydroborate体系中,用 甲醇 用作溶剂,化学反应生成1-苯并噻吩-2-甲醇
参考文献:杂芳基丙烯酸酯和丙氨酸与欧芹中的苯丙氨酸氨裂解酶的相互作用.
标题:杂芳基丙烯酸酯和丙氨酸与欧芹中的苯丙氨酸氨裂解酶的相互作用.
摘要:合成了在β位置被杂芳基取代的丙烯酸和丙氨酸,并进行了光谱表征(uv,Hrms,(1)h NMR和(13)c NMR光谱).杂芳基基团是呋喃基,噻吩基,苯并呋喃基和苯并噻吩基,并且在2-或3-位含有丙酰基侧链.前者是苯丙氨酸解氨酶(pal)的非常好底物,而后者是抑制剂.例外的是噻吩-3-基丙氨酸(一种中等的底物)和呋喃-3-基丙氨酸(惰性).讨论了这些例外的可能原因.从外消旋杂芳基-2-丙氨酸开始,它们的d-对映异构体通过立体破坏方法制备.由杂芳基-2-丙烯酸酯以高氨浓度制备杂芳基-2-丙氨酸的l-对映异构体.
Doi:10.1002/chem.200501034

专利信息

专利号:US-4388310-A
优先权日:1982-03-01
标 题:6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
发明人：CHRISTENSEN BURTON G; DININNO FRANK P; MUTHARD DAVID A; RATCLIFFE RONALD W
权利人:MERCK & CO INC
摘要:Disclosed are 6-amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids (I) which are useful as antibiotics and as intermediates in the synthesis of substituted pen-2-em-3-carboxylic acids: I wherein: R1 is H or acyl; R2 is hydrogen or methoxyl; R3 is alkyl having from 1-6 carbon atoms; phenylalkyl having 7-12 carbon atoms; and cycloalkyl having 3-6 carbon atoms; and R4 is hydrogen, a removable protecting group or a pharmaceutically acceptable salt or ester moiety.

专利号:US-5637719-A
优先权日:1989-06-09
标 题 :Reagents for rapid peptide synthesis
发明人：CARPINO LOUIS A; PHILBIN MICHAEL
权利人:RES CORP TECHNOLOGIES INC
摘要:The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is directed to a method of protecting an amino group of an organic molecule during a reaction which modifies a portion of the molecule other than the protected amino group.

专利号:EP-0401817-B1
优先权日:1989-06-09
标题 :Reagents for rapid peptide synthesis
发明人：CARPINO LOUIS A; PHILBIN MICHAEL
权利人:RES CORP TECHNOLOGIES INC
摘要:This invention relates to compounds of the formula: wherein R is an electron withdrawing group; R1 is H or COZ; X1 and X2 are independently H, lower alkyl, aryl, aryl lower-alkyl or polystyrene or R and X1 taken together with the carbon atoms to which they are attached form a ring containing from 4 to 15 ring carbon atoms and may contain up to 2 heteroatoms, wherein the heteroatoms are O, S, or N; and Z is an amino acid residue, a peptide residue or a leaving group. The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is also directed to a method of protecting an amino group of an organic molecule during a reaction which modifies a portion of the molecule other than the protected amino group.

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:JP-2832643-B2
优先权日:1989-10-23
标题:Synthesis of amino acid fluorides as peptide coupling agents and their use

专利号:JP-H05502029-A
优先权日:1989-10-23
标题:Synthesis of amino acid fluorides as peptide coupling agents and their uses