CAS: 431-21-0; 2,3-Dibromo-1,1,1-Trifluoropropane

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CAS号677-21-4 3,3,3-三氟丙烯 | CAS号460-35-5 1-氯-3,3,3-三氟丙烷 | CAS号17760-01-9 2,3-dibromo-1,1... | CAS号600-05-5 2,3-二溴丙酸 | CAS号7783-56-4 三氟化锑 | CAS号421-46-5 2-溴-1,1,1-三氟丙烷 | CAS号384-64-5 alpha-(三氟甲基)苯乙烯 | CAS号188739-86-8 alpha-Trifluoro... | CAS号661-54-1 3,3,3-三氟-1-丙炔 | CAS号1514-82-5 2-溴-3,3,3-三氟丙烯 | CAS号775320-72-4 3-(t-butyloxy)-... | CAS号105935-24-8 2-三氟甲基丙烯酸叔丁酯 | CAS号136476-28-3 1-(3,3,3-triflu... | CAS号85199-73-1 3-methyl-5-(tri... | CAS号85199-74-2 1-methyl-5-(tri...

3,3,3-三氟丙烯置于溴体系中,化学反应生成 1,2-二溴-3,3,3-三氟丙烷
参考文献:2-溴-3,3,3-三氟丙烯的热分解及其灭火机理的研究
标题:2-溴-3,3,3-三氟丙烯的热分解及其灭火机理的研究
摘要:作为一种新型的哈龙替代品,2-溴-3,3,3-三氟丙烯(btp)的灭火效果非常好,灭火浓度低于哈龙1301.尽管btp的物理性质和灭火特性已有所改善.广泛报道的是,关于其热解和灭火机理的研究相对较少.在这项研究中,研究了btp在25-800oc的温度范围内的热分解,并通过gc和gc-Ms分析了分解产物.实验结果表明,分解产物主要三氟(cf 3 Cch)和/或溴三氟(cf 3Br).通过一阶反应近似计算得出的btp热裂解的表观活化能与高斯03的理论计算结果非常吻合.此外,通过分析分解产物及其化学抑制作用,Btp的热分解机理及其化学熄灭.然后提出了高温下的机理.
DOI:10.1016/j.Jfluchem.2013.05.008

专利信息

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-7179794-B2
优先权日:1998-06-08
标题 :Multivalent macrolide antibiotics
发明人：GRIFFIN JOHN H; PACE JOHN L
权利人:THERAVANCE INC
摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.