CAS: 4635-08-9; 5-Bromopyridine-3,4-Diamine

相似化合物

89284-05-9 1044771-99-4 221241-11-8

上下游产品

4-amino-3-bromo-5-nitropyridine 4-amino-3-nitropyridine 4-aminopyridine 4-(nitroamino)pyridine pyridin-2-one7-bromo-1,3-dihydro-2H-imidazo4,5-cpyridin-2-one N-(2,3-diphenylpyrido[3,4-b]pyrazin-8-yl)benzophenone imine N-[2,3-bis(4-methoxyphenyl)pyrido[3,4-b]pyrazin-8-yl]benzophenone imine 8-amino-2,3-diphenylpyrido[3,4-b]pyrazine

4-氨基-3-硝基吡啶置于水,Potassium Acetate,溶剂黄146,Tin(Ll) Chloride体系中,用 乙醇 作为反应溶剂,化学反应 3.0H,反应生成 5-溴-3,4-二氨基吡啶
参考文献:新型2,3,8-三取代吡啶并[3,4-B]吡嗪和吡啶并[2,3-B]吡嗪的制备
标题:新型2,3,8-三取代吡啶并[3,4-B]吡嗪和吡啶并[2,3-B]吡嗪的制备
摘要:八步合成8-溴-2,3-二取代的吡啶并[3,4-B]吡嗪和六步合成8-氨基-2,3-二取代的吡啶并[3,4-B]吡嗪已开发.该合成路线的特别有价值的特征是可以构建在位置8(苯胺,酰胺,尿素,硫脲)具有多种取代基的2,3-二取代的吡啶并[3,4-B]吡嗪.我们的协议扩展到2,3,8-三取代吡啶并[2,3-B]吡嗪的合成. 吡啶并[3,4-B]吡嗪-吡啶并[2,3-B]吡嗪-二氨基吡啶-尿素-硫脲-酰胺
DOI:10.1055/s-0030-1259429

专利信息

专利号:US-9708336-B2
优先权日:2014-01-22
标题 :Metallo-beta-lactamase inhibitors
发明人：MANDAL MIHIR; TANG HAIFENG; XIAO LI; SU JING; LI GUOQING; YANG SHU-WEI; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; HICKS JACQUELINE; LOMBARDO MATTHEW; CHU HONG; HAGMANN WILLIAM; PASTERNAK ALEX; GU XIN; JIANG JINLONG; DONG SHUZHI; DING FA-XIANG; LONDON CLARE; BISWAS DIPSHIKHA; YOUNG KATHERINE; HUNTER DAVID N; ZHAO ZHIQIANG; YANG DEXI
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

专利号:CA-2482705-A1
优先权日:2002-04-17
标题:Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin

专利号:CA-2482705-C
优先权日:2002-04-17
标题 :Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin