CAS: 549-32-6; 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One

该化合物是来自Reynoutria japonica(日本结叶)等植物的氟氯素胶层,该化合物具有显著的抗氧化特性,有效清除了自由基和减轻氧化性压力,其结构与quercetin相似,可以进行类似的生物活动,包括潜在的抗炎和血管保护效应.Reynoutrin在生理条件下表现出稳定性,比一些丙烯氟芳类植物更具生物利用率.研究表明,在营养素和药物中应用,特别是用于支持心血管健康和减少细胞损害,其水溶性和中度代谢稳定性进一步有助于其配方的用途.分析方法确认高纯度,使其适合标准化提取物.

英文名称2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One
中文名称槲皮素-3-D-木糖甙
IUPAC名称2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
CAS编号549-32-6
MFCD编号:MFCD29050264
分子式:C20H18O11
分子量:434.35
产品CID: 2502240
产品分类天然产物 → 黄酮类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: PZZRDJXEMZMZFD-DUYPVGENSA-N
InChI=1S/C20H18O11/c21-8-4-11(24)14-13(5-8)30-18(7-1-2-9(22)10(23)3-7)19(16(14)27)31-20-17(28)15(26)12(25)6-29-20/h1-5,12,15,17,20-26,28H,6H…
计算化学: 氢键受体数11.0氢键供体数7.0可旋转键数3.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P261-P305+P351+P338
UN编号NONH for all modes of transport
WGK Germany3

上下游产品

CAS号117-39-5 槲皮素 | CAS号357194-03-7 2-(2,2-diphenyl... | CAS号742062-21-1 (2S,3R,4S,5R)-2...

合成工艺路线路线简述

(2S,3R,4S,5R)-2-((2-(2,2-Diphenylbenzo[d][1,3]Dioxol-5-yl)-5,7-Dihydroxy-4-Oxo-4H-Chromen-3-yl)Oxy)Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate置于palladium On Activated Charcoal 甲醇,氢气,Sodium Methylate体系中,化学反应生成槲皮素 3-Beta-D-吡喃木糖苷
参考文献:Synthesis And Biological Evaluation Of Flavonoids As Vasorelaxant Agents
标题:Synthesis And Biological Evaluation Of Flavonoids As Vasorelaxant Agents
摘要:Several 5,7-Dihydroxyflavone And Quercetin 3-O-Glycosides Have Been Synthesized And Evaluated For Vasorelaxant Activity. A Logp-Activity Relationship Amongst Flavonoids Was Suggested. (C) 2004 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2004.05.061

海关参考信息

2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.