CAS: 619-41-0; 2-Bromo-1-(P-Tolyl)Ethanone

上下游产品

CAS号122-00-9 对甲基苯乙酮 | CAS号13664-98-7 2,2-二溴-4'-甲基苯乙酮 | CAS号622-97-9 4-甲基苯乙烯 | CAS号598-21-0 溴乙酰溴 | CAS号108-88-3 甲苯 | CAS号60655-81-4 (±)-2-bromo-1-(... | CAS号536-50-5 1-(4-甲基苯基)乙醇 | CAS号766-97-2 4-乙炔基甲苯 | CAS号1075-47-4 4-甲基苯甲酰甲醛水合物 | CAS号104940-91-2 1-(4-methylphen... | CAS号5467-70-9 4-甲基-α-氨基苯乙酮盐酸盐 | CAS号3343-45-1 1-(4-溴苯基)-2-羟基乙基-1-酮 | CAS号586-70-9 1-(4-甲基苯基)乙胺 | CAS号142016-38-4 2-对甲砜基咪唑[1,2-A]... | CAS号1022-45-3 2-苯基-4-[3H]喹唑啉酮 | CAS号14271-73-9 4-甲基苯甲酰基丁酯 | CAS号4765-56-4 2-苄基喹唑啉-4(1H)-酮 | CAS号142074-20-2 6-氯-2-甲苯咪唑并[1,2-A]嘧啶

Alpha-甲基苯乙烯置于dipotassium Peroxodisulfate,Potassium Bromide体系中,用 水 作为反应溶剂,化学反应 12.0H,以72%的收率获得产物2-溴-4'-甲基苯乙酮
参考文献:通过k 2 S 2 O 8介导的串联羟基溴化和苯甲醛合成苯甲酰溴.氧化作用 的 苯乙烯类 在水里
标题:通过k 2 S 2 O 8介导的串联羟基溴化和苯甲醛合成苯甲酰溴.氧化作用 的 苯乙烯类 在水里
摘要:非过渡金属催化的苯甲酰溴的合成是通过k 2 S 2 O 8介导的串联羟基溴化和氧化作用 的 苯乙烯类.该反应的优点是出色的官能团相容性,温和的反应条件(60oc)和纯净的使用水作为反应介质.基于实验观察,提出了合理的反应机理.
DOI:10.1039/c3Gc40515J

专利信息

专利号:WO-2021038581-A1
优先权日:2019-08-30
标题 :A one step synthesis of 2-substituted benzo[b]thiophenes
发明人：SEKAR GOVINDASAMY; POONGUZHALI ELAMVAZHUTHI
权利人:INDIAN INST TECH MADRAS
摘要:The invention pertains to a one step synthesis of 2-substituted benzo[ b ]thiophene of general formula wherein the synthesis of 2-substituted benzo[ b ]thiophenes is by reacting the starting materials substituted or unsubstituted 2-halogenobenzaldehyde and substituted or unsubstituted acetyl/phenacyl bromide with a catalyst, a sulphur source and phase transfer catalyst in an aqueous medium with atmospheric air and at temperature in the range of 25°C-30°C.

专利号:US-9150840-B2
优先权日:2011-08-26
标题 :Isolated bacterial strain of Achromobacter sp. MTCC 5605 and a highly enantioselective epoxide hydrolase isolated therefrom
发明人：KAMAL AHMED; KHANNA ROHINI; KUMAR CHITYAL GANESH; SHAIK ANVER BASHA; KUMAR MATAM SHIVA
权利人:KAMAL AHMED; KHANNA ROHINI; KUMAR CHITYAL GANESH; SHAIK ANVER BASHA; KUMAR MATAM SHIVA; COUNCIL SCIENT IND RES
摘要:The present invention relates to a novel epoxide hydrolase enzyme which aims to achieve a high degree of resolution towards a broader range of substrates with high enantioselectivity and yields with minimal product inhibition. The invention further relates to a new bacterial strain Achromobacter sp. MTCC 5605 isolated from a petroleum-contaminated sludge sample, capable of producing the said enzyme. It is notable that the enzyme can be used as whole bacterial cell preparation, which allows continuous hydrolysis of substrates at even higher concentration and have an advantage of being recycled. The invention further relates to a process for the hydrolysis of different aryl epoxides which are potential synthons of intermediates for the synthesis of chiral amino alcohols and bioactive compounds like β-blockers.

专利号:US-8101633-B2
优先权日:2006-06-05
标 题 :Preparation and utility of substituted imidazopyridine compounds with hypnotic effects
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:GANT THOMAS G; SARSHAR SEPEHR; AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of GABA A receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of sleep disorders and/or for providing a patient in need with a hypnotic, anxiolytic or anti-convulsive effect are described.

专利号:US-8906915-B2
优先权日:2009-12-17
标 题:Compounds, compositions, and methods for controlling biofilms
发明人：DE KEERSMAECKER SIGRID; DE VOS DIRK; ERMOLATEV DENIS; STEENACKERS HANS; VAN DER EYCKEN ERIK; VANDERLEYDEN JOZEF; SAVALIYA BHARAT S
权利人:DE KEERSMAECKER SIGRID; DE VOS DIRK; ERMOLATEV DENIS; STEENACKERS HANS; VAN DER EYCKEN ERIK; VANDERLEYDEN JOZEF; SAVALIYA BHARAT S; UNIV LEUVEN KATH
摘要:The invention relates to substituted 2-aminoimidazoles and their imidazo[1,2-a]pyrimidinium salts precursors being active against biofilm formation. The invention also relates to imidazo[1,2-a]pyrimidinium salts bearing an azidoalkyl substituent, and to substituted 2-aminoimidazoles wherein the amino group bears a terminal heterocyclic group such as a triazolyl group which are formed through azide-alkyne Huisgen cycloaddition starting from said imidazo[1,2-a]pyrimidinium salts bearing an azidoalkyl substituent. The invention also relates to a class of N-(azidoalkyl)pyrimidin-2-amines useful as starting materials for the synthesis of said imidazo[1,2-a]pyrimidinium salts bearing an azidoalkyl substituent. The invention also relates to antimicrobial compositions that include a microbial biofilm formation inhibiting amount of such substituted 2-aminoimidazoles or imidazo[1,2-a]pyrimidinium salts in combination with excipients. Methods for inhibiting or controlling microbial biofilm formation in a plant, a body part of a human or an animal, or a surface with which a human or an animal may come into contact are also disclosed.

专利号:US-8829014-B2
优先权日:2006-04-07
标题 :Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers
发明人：GIORDANO ANTHONY; VASU KAMALA K; THAKAR HARDIK M; GIRI RAJAN S; SUDARSANAM VASUDEVAN; YERANDE SWAPNIL G; INAMDAR GAJANAN S
权利人:GIORDANO ANTHONY; VASU KAMALA K; THAKAR HARDIK M; GIRI RAJAN S; SUDARSANAM VASUDEVAN; YERANDE SWAPNIL G; INAMDAR GAJANAN S; UNIV LOUISIANA STATE; PATEL PHARMACEUTICAL EDUCATION & RES DEV PERD CT B V
摘要:Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.

专利号:CN-107686481-A
优先权日:2017-09-28
标题:A method for ultrasonic solvent-free synthesis of thiazole derivatives containing acetophenone triazole groups