CAS: 110-64-5; Z/e-But-2-Ene-1,4-Dio

相似化合物

821-11-4 25260-60-0 57323-06-5

上下游产品

1,4-dibromo-2-butene epoxybutene 1,4-dichloro-2-butene L-Tartaric acid 3-chlorotetrahydrofuran 2,5-dihydrofuran 2,5-Divinyl-[1,4]dioxan 2,3-dibromo-1,4-dihydroxy-2-butane

顺式-1,2-二羟甲基乙烯置于c34H45Cl2N2Oru(1+)*c4H9O3S(1-)体系中,用 异丙醇 用作溶剂,化学反应 3.0H,以56%的收率获得1,4-丁烯二醇
参考文献:迈向可持续催化-使用相标记的环烷基氨基碳烯(caac)钌催化剂在质子介质中高效烯烃复分解
标题:迈向可持续催化-使用相标记的环烷基氨基碳烯(caac)钌催化剂在质子介质中高效烯烃复分解
摘要:已经合成了新一代的hoveyda和双卡宾型钌基烯烃复分解催化剂(10和12),其中包含阳离子环烷基氨基卡宾(caac)配体.该催化剂在对环境无害的质子介质中显示出卓越的稳定性和活性.Oh官能化原料(例如rcm,Romp Cm)的各种烯烃复分解反应可以在甲醇,异丙醇,水或甲醇/水溶剂混合物中的催化剂负载量低至0.05 Mol%的条件下进行,从而实现了迄今为止报道的最低的催化剂负载量在这些媒体中.还已经证明了质子介质中可再生原料(包括磷脂(23)和植物油(20))的烯烃易位.
Doi:10.1002/cctc.201902258

专利信息

专利号:US-7956011-B2
优先权日:2005-05-04
标题:Materials and methods for the photodirected synthesis of oligonucleotide arrays
发明人：SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN
权利人:CANCER RES INST ROYAL
摘要:Materials and methods for photodirected synthesis of oligonucleotide arrays on a solid substrate by photodirected synthesis are disclosed which employ a film formed from (i) a photoacid generator that on photolysis generates acid that is capable of directly removing the protecting group of the linker molecules or oligonucleotides and (ii) a polymer substantially lacking electronegative heteroatoms that are capable of hydrogen bonding with photogenerated acid. Methods of synthesizing an oligomer arrays are also described that use a film that restricts diffusion of reactants and products on the substrate during synthesis of the array and which includes a precursor of a deprotecting reagent. The method involves removing one or more of the non-required products of the deprotection reaction from the reactive array elements at which they are produced during the reaction, in order to displace the deprotection reaction towards completion.

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-4108870-A
优先权日:1977-06-06
标 题:Stereocontrolled synthesis of α-multistriatin
发明人：FRIED JOSEF; ELLIOTT WILLIAM J
权利人:UNIV CHICAGO
摘要:A practical stereocontrolled synthesis of a mixture containing a major amount of α-multistriatin and a minor amount of γ-multistriatin in an overall yield of about 73% from cis-2-butene-1,4-diol is provided. α-Multistriatin is one of the three essential components of the aggregation pheromone of the European elm bark beetle.

专利号:US-9409945-B2
优先权日:1999-10-04
标 题 :Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
发明人：DESLONGCHAMPS PIERRE; DORY YVES; BERTHIAUME GILLES; OUELLET LUC; LAN RUOXI
权利人:OCERA THERAPEUTICS INC
摘要:A library of macrocyclic compounds of the formula (I) n n n n n n n n n n n n where part (A) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) y — bivalent radical or a covalent bond; n where part (B) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) z — bivalent radical, or a covalent bond; n where part (C) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) t — bivalent radical, or a covalent bond; and n where part (T) is a —Y-L-Z— radical wherein Y is CH 2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.

专利号:US-12365760-B2
优先权日:2019-05-13
标题 :Process for the synthesis of polycarbonates from cyclic monothiocarbonates
发明人：RUDOLF PETER; THIEL INDRE; WURM THOMAS MAXIMILIAN
权利人:BASF SE
摘要:A process can be used for the synthesis of compounds containing at least one non-cyclic carbonate group, wherein a compound A) containing at least one five-membered cyclic monothiocarbonate group is reacted with at least one hydroxy group of a compound B) or of compound A) itself.