CAS: 167171-03-1; (R)-2-(2-(Diphenylphosphino)Phenyl)-4-Phenyl-4,5-Dihydrooxazole

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diphenylphosphane (4R)-2-(2-fluorophenyl)-4-phenyl-4,5-dihydro-1,3-oxazole potassium diphenylphosphine D-2-phenylglycinol

L-苯甘氨酸置于copper(L) Iodide,Lithium Aluminium Tetrahydride,氯苯,Zinc(II) Chloride体系中,用 四氢呋喃,甲苯 用作溶剂,化学反应 6.34H,反应生成(R)-(-)-2-[2-(二苯基膦)苯基]-4-苯基-2-噁唑啉
参考文献:铜(i)膦恶唑啉配合物:配体取代和立体需求对电化学和光物理性质的影响.
标题:铜(i)膦恶唑啉配合物:配体取代和立体需求对电化学和光物理性质的影响.
摘要:合成了七个基于异双峰p ^ N配体的纯铜cui复合物,并对其进行了全面的表征.为了研究结构-性质之间的关系,系统地改变了膦恶唑啉(phox)配体上取代基的类型,大小,数量和构型.为此,X射线衍射,NMR光谱,稳态吸收和发射光谱,时间分辨发射光谱,猝灭实验和循环伏安法的组合被用于评估光物理和电化学性质.此外,基于时间的密度泛函理论计算也被用来分析激发态的结构和特性.令人惊讶的是,发现对各个p ^ N配体的手性有很强的依赖性,而不同取代基的具体种类和大小对溶液的性质影响很小.最重要的是,除c3以外的所有配合物在溶液中都是光稳定的,并显示出完全可逆的氧化还原过程.牺牲性还原剂被施加以证明在光照射下成功的电子转移.这些特性使这类光敏剂成为太阳能转化问题的潜在候选者.
Doi:10.1002/chem.201904379

专利信息

专利号:US-9518034-B2
优先权日:2013-10-14
标题 :Synthesis of chiral enaminones, their derivatives, and bioactivity studies thereof
发明人：STOLTZ BRIAN M; DOUGHERTY DENNIS A; DUQUETTE DOUGLAS; DUFFY NOAH
权利人:CALIFORNIA INST OF TECHN
摘要:This invention provides enantioenriched heterocyclic enaminone compounds with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I): n ncomprising treating a compound of formula (II):n n nwith a transition metal catalyst under alkylation conditions.

专利号:US-11377396-B2
优先权日:2014-12-18
标题 :Enantioselective synthesis of α-quaternary Mannich adducts by palladium-catalyzed allylic alkylation
发明人：STOLTZ BRIAN M; NUMAJIRI YOSHITAKA; PRITCHETT BEAU P; CHIYODA KOJI
权利人:CALIFORNIA INST OF TECHN
摘要:This invention provides enantioenriched Mannich adducts with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I): n ncomprising treating a compound of formula (II):n n nwith a transition metal catalyst under alkylation conditions.

专利号:US-2016096810-A1
优先权日:2014-10-07
标 题 :Enantioselective synthesis of dialkylated n,o-heterocycles by palladium-catalyzed allylic alkylation
发明人：STOLTZ BRIAN M; NUMAJIRI YOSHITAKA; BEHENNA DOUGLAS C
权利人:STOLTZ BRIAN M; NUMAJIRI YOSHITAKA; BEHENNA DOUGLAS C
摘要:This invention provides enantioenriched N,O-heterocyclic compounds with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I): n n n n n n n n n n comprising treating a compound of formula (II): n n n n n n n n n n with a transition metal catalyst under alkylation conditions.

专利号:US-2020157020-A1
优先权日:2014-12-18
标题:Enantioselective synthesis of alpha-quaternary mannich adducts by palladium-catalyzed allylic alkylation

专利号:US-2015105552-A1
优先权日:2013-10-14
标 题 :Synthesis of chiral enaminones, their derivatives, and bioactivity studies thereof

专利号:US-2016176773-A1
优先权日:2014-12-18
标 题 :ENANTIOSELECTIVE SYNTHESIS OF alpha-QUATERNARY MANNICH ADDUCTS BY PALLADIUM-CATALYZED ALLYLIC ALKYLATION