CAS: 18063-02-0; 2,6-Difluorobenzoyl Chloride

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CAS号385-00-2 2,6-二氟苯甲酸 | CAS号372-18-9 1,3-二氟苯 | CAS号110623-36-4 5-(2,6-difluoro... | CAS号60731-73-9 2,6-二氟苯甲酰异氰酸酯 | CAS号385-00-2 2,6-二氟苯甲酸 | CAS号13671-00-6 2,6-二氟苯甲酸甲酯 | CAS号19064-14-3 2,6-二氟苯甲酸乙酯 | CAS号443797-96-4 4-[[5-氨基-1-(2,6... | CAS号35367-38-5 氟脲杀 | CAS号122987-01-3 N-(4-氯苯基)-2,6-二氟苯甲酰胺 | CAS号869363-13-3 4-[[9-氯-7-(2,6-... | CAS号1897-52-5 2,6-二氟苯腈

1,3-二氟苯置于氯化亚砜体系中,化学反应生成2,6-二氟苯甲酰氯
参考文献:The Synthesis And Activity Of Some 2,6-Difluorophenyl-Substituted Compounds
标题:The Synthesis And Activity Of Some 2,6-Difluorophenyl-Substituted Compounds
摘要:
Doi:10.1021/jm00310A026

专利信息

专利号:RU-2440355-C2
优先权日:2006-04-03
标 题:Method for synthesis of organoelement compounds

专利号:US-7109220-B2
优先权日:2003-11-19
标 题:Amino substituted pyridinyl methanone compounds useful in treating kinase disorders
发明人：LIN RONGHUI; WETTER STEVEN K; LU YANHUA; CONNOLLY PETER J; EMANUEL STUART; GRUNINGER ROBERT H; MIDDLETON STEVEN A
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention provides amino substituted pyridinyl methanone compounds; pharmaceutical compositions comprising the compounds and methods of synthesis thereof. The compounds, which are cyclin dependent kinase (CDK) inhibitors, can be used to treat or ameliorate CDK mediated disorders. The invention thus also provides the therapeutic or prophylactic use of the compounds and/or pharmaceutical compositions to treat such disorders.

专利号:EP-1641453-B1
优先权日:2003-06-25
标题 :Product containing at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent
发明人：PREVOST GREGOIRE; BREZAK PANNETIER MARIE-CHRISTINE; DIOLEZ CHRISTIAN
权利人:IPSEN PHARMA
摘要:The invention relates to a product containing at least one phosphatase Cdc25 inhibitor combined with at least one other anticancer agent for simultaneous, separate or staggered therapeutic use during treatment for cancer. According to the invention, the other anticancer agent is preferably selected from: DNA base analogs such as 5-fluorouracil; inhibitors of type I and/or type II topoisomerases, such as camptothecin and the analogs thereof, doxorubicin or amsacrine; compounds interacting with the cellular spindle, for example, paclitaxel (Taxol); compounds acting on the cytoskeleton, such as vinblastine; inhibitors of the transduction of the signal passing via the heterotrimeric G proteins; prenyltransferase inhibitors, and especially farnesyltransferase inhibitors; cyclin-dependent kinase (CDKs) inhibitors; alkylating agents such as cisplatin; folic acid antagonists such as methotrexate; and inhibitors of DNA synthesis and cellular division, such as mitomycin C. The invention also relates to (1R)-1-[({(2R)-2-amino--3-[(8S)-8-(cyclohexylmethyl)-2-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl]--3-oxopropyl}dithio)methyl]-2-[(8S)-8-(cyclohexylmethyl)-2-phenyl--5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl]-2-oxoethylamine, or the pharmaceutically acceptable salts thereof, that can be used as anticancer agents.

专利号:RU-2142949-C1
优先权日:1993-07-21
标题:Derivatives of 3,6-substituted-1,2,4,5-tetrazine, methods of their synthesis, larvicide and ovicide-active composition, method of its preparing and method of decrease of amount of mite larvae and eggs

专利号:RU-1806128-C
优先权日:1991-05-12
标题 :Method of 2,6-difluorobenzoyl chloride synthesis

专利号:CN-111004150-B
优先权日:2019-12-18
标题 :Synthesis method of substituted benzoyl isocyanate