CAS: 1986-81-8; 3-Carbamoylpyridine 1-Oxide

上下游产品

1-oxy-nicotinic acid methyl ester 1-oxy-nicotinic acid ethyl ester nicotinamide 3-cyano-1-methylpyridinium iodide2-Cyano-5-carboxamidopyridine 3-cyanopyridine N-oxide 2-hydroxy-N-acetylnicotinamide N-acetyl-2-hydroxynicotinamide

烟酰胺置于双氧水,碳酸氢钠,三氯乙腈体系中,用 四氢呋喃,水 用作溶剂,化学反应 12.0H,以65%的收率获得n-氧代烟酰胺
参考文献:三氯乙腈-过氧化氢:一种用于叔胺和仲胺选择性氧化的简单有效的系统
标题:三氯乙腈-过氧化氢:一种用于叔胺和仲胺选择性氧化的简单有效的系统
摘要:使用三氯乙腈-过氧化氢系统将各种叔胺和仲胺分别有效地氧化为相应的n-氧化物和硝酮.原位生成的三氯甲基过氧亚氨酸是氧化过程的活性试剂.
Doi:10.1016/j.Tetlet.2014.03.017

专利信息

专利号:US-8722852-B2
优先权日:2006-04-28
标 题 :Cosmetic composition for stimulating the synthesis of proteins of the basement membrane
发明人：ZIEGLER HUGO; IMFELD DOMINIK; STOCKLI MARTIN; HEIDL MARC
权利人:ZIEGLER HUGO; IMFELD DOMINIK; STOCKLI MARTIN; HEIDL MARC; DSM IP ASSETS BV
摘要:Cosmetic composition which can be applied topically, comprising at least one compound of the general formula (I) in which R 1 is H, C 1 -C 20 -alkyl, cycloalkyl or aryl-C 1 -C 4 -alkyl, n is 1-4, X is —O—, —NH— or —NR 2 — and R 2 H or C 1 -C 20 -alkyl; and at least one compound corresponding to the above formula (I) but in which XR 1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid; use of these compounds and of the composition for stimulating the synthesis of the proteins of the basement membrane; and also both those compounds of the formula (I) in which X is —NR 2 — and both R 1 and R 2 are different from H, and the compounds corresponding to formula (I) but in which XR 1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid, as such.

专利号:US-6150403-A
优先权日:1997-10-14
标 题 :Topical compositions for regulating the oily/shiny appearance of skin
发明人：BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J
权利人:PROCTER & GAMBLE
摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.

专利号:US-2009155347-A1
优先权日:2006-04-28
标题 :Cosmetic Composition for Stimulating the Synthesis of Proteins of the Basement Membrane

专利号:WO-02053544-A1
优先权日:2000-12-29
标题 :Pharmaceutical uses and synthesis of nicotinanilide-n-oxides

专利号:CA-2650578-A1
优先权日:2006-04-28
标 题 :Cosmetic composition for stimulating the synthesis of proteins of the basement membrane

专利号:US-8293712-B2
优先权日:2006-04-28
标 题 :Cosmetic composition for stimulating the synthesis of proteins of the basement membrane