专利号:WO-2023064991-A1 优先权日:2021-10-22 标题 :Process for preparing bicyclic glycine-proline compounds and monocyclic glycine-proline intermediates thereof 发明人:SCOTT JEREMY PETER; KEEN STEPHEN PHILIP; ESPENSEN GEORGE MAX; PARRY-JONES DAVID; LAWRENCE RONNIE MAXWELL; BLOWER CLIVE JOHN 权利人:NEUREN PHARMACEUTICALS LTD 摘要:The present disclosure generally relates to a process for the synthesis of bicyclic glycine-proline compounds, and monocyclic glycine-proline intermediates thereof. In particular, the present disclosure also relates to a process for the synthesis of cyclic G-2-AllylP and its analogues. The present disclosure also relates to a process for the synthesis of optionally protected monocyclic glycine-proline intermediates. The present disclosure also relates to a process for the synthesis of esterified glycine-proline intermediates. The present disclosure also relates to compounds prepared by the processes and the use of such compounds to prepare compositions and to treat disorders.
参考标题:Design Of Photoaffinity Labeling Probes Derived From 3,4,5-Trimethylfuran-2(5 H )-One For Mode Of Action Elucidation 作者:Martin Pošta,Vilmos Soós,Petr Beier |发布日期:2016.7 摘要:Herein We Report The Synthesis Of New Probes For Photoaffinity Labeling With The Aim Of Receptor Identification And Mode Of Action Elucidation Of 3,4,5-Trimethylfuran-2(5H)-One (Tmb), Recently Identified In The Smoke Of Burning Vegetation As An Efficient Seed Germination Inhibitor. These Photoaffinity Probes Consist Of An Ethynyl Group That Acts As A Tag For Introduction Of An Optional Detectable Marker
合成参考文献
摘要:Stará, I. G.; Starý, I., Science of Synthesis, (2010) 45, 905.