CAS: 3264-21-9; 1-(Pyren-1-yl)Ethanone

该化合物是一种有机化合物,属于多环芳烃族,其结构特征包括一个带有乙酰集团的发球细胞,通常是黄色至橙色晶状固体,具有相对较高的熔点.该化合物以其荧光特性而著称,在各种应用中,包括在生物化学研究中作为荧光探针的作用.1-乙酰丙烯在丙酮和乙醇等有机溶剂中是可溶的,但在水中溶解性有限.其化学配方为C15H10O,其分子重量反映了其复杂的结构.该化合物在与环境化学有关的研究中的潜在作用以及生物系统中多环芳烃的行为方面,对研究很感兴趣.然而,与许多多环芳烃化合物一样,它可能对环境和健康造成危害,需要小心地处理和处置.

结构式图片

相似化合物

3029-19-4 252338-01-5 80480-15-5

上下游产品

1-(8-乙酰基芘-1-基)乙酮 1,8-Bis(Acetyl)Pyrene 86471-06-9
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合成工艺路线路线简述

    芘置于aluminum Tri-Bromide,Lithium Carbonate体系中,用 四氯化碳,二氯甲烷 用作溶剂,化学反应 23.67H,反应生成1-乙酰基芘
    参考文献:A Very Convenient Synthesis Of Cyclopenta[cd]Pyrene
    标题:A Very Convenient Synthesis Of Cyclopenta[cd]Pyrene
    摘要:
    Doi:10.1021/jo00289A062

    海关参考信息

    专利信息


    专利号:EP-1501848-B1
    优先权日:2002-05-08
    标 题 :Synthesis of locked nucleic acid derivatives
    发明人:SORENSEN MADS DETLEF; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
    权利人:SANTARIS PHARMA AS
    摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as alpha-L-oxy-LNA, amino-LNA, alpha-L-amino-LNA, thio-LNA, alpha-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues. (Formula I)

    专利号:US-6432294-B1
    优先权日:2000-12-14
    标题 :Electrochemical activation of organic disulfides for electrophilic substitution
    发明人:GLASS RICHARD S; JOUIKOV VIATCHESLAV V; BOJKOVA NINA V
    权利人:UNIV ARIZONA
    摘要:Electrochemical oxidation of organic disulfides is conducted in an electrolytic solution containing an arene (e.g., anthracene, acenaphthylene, phenanthrene), and depending on the arene used and/or the product desired, an organic base (e.g., pyridine) to effect the synthesis of organothiated products in good yields.

    专利号:US-6207838-B1
    优先权日:1999-04-30
    标 题 :Electrochemically generated organothiating reagents and their use
    发明人:GLASS RICHARD S; JOUIKOV VIATCHESLAV V
    权利人:UNIV ARIZONA
    摘要:Electrolysis of organic disulfides in liquid sulfur dioxide is used to obtain organothiating agents, which can then be reacted with appropriate substrates to effect the synthesis of organothioaromatic compounds efficiently and in high yields. With appropriate phenolic compounds, regioselective substitution occurs in which para substitution greatly exceeds ortho substitution.

    专利号:US-7569575-B2
    优先权日:2002-05-08
    标题 :Synthesis of locked nucleic acid derivatives

    专利号:CN-106632319-A
    优先权日:2016-11-17
    标 题:A kind of 2-(pyrene-1-yl)-1,8-naphthyridine and its synthesis method
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    主要参考文献

    [参考文献]: Tsutomu Shimada, Et Al. Binding Of Diverse Environmental Chemicals With Human Cytochromes P450 2A13, 2A6, And 1B1 And Enzyme Inhibition. Chem Res Toxicol. 2013 Apr 15;26(4):517-28.

    合成参考文献


    摘要:Wu, F.; Zhu, S., Science of Synthesis Knowledge Updates, (2020) 1, 164.
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