CAS: 78712-43-3; (E)-3-(4-((1H-Imidazol-1-yl)Methyl)Phenyl)Acrylic Acid Hydrochloride

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CAS号141-82-2 丙二酸 | CAS号102432-03-1 4-(1H-咪唑-1-甲基)苯甲醛 | CAS号1145685-38-6 (E)-4-(hydroxym... | CAS号18282-51-4 4-碘苄醇

4-碘苄醇置于四丁基醋酸铵,三乙胺,Sodium Hydroxide体系中,用 N-甲基吡咯烷酮,甲醇,水 作为反应溶剂,化学反应 51.0H,反应生成 盐酸奥扎格雷
参考文献:钯-纳米粒子和硅-纳米线阵列混合体:催化异构反应的平台
标题:钯-纳米粒子和硅-纳米线阵列混合体:催化异构反应的平台
摘要:我们报告了硅纳米线阵列稳定的钯纳米粒子催化剂sina-Pd的开发.它在钯催化的mizoroki-Heck反应,烯烃的氢化,硝基苯的氢解,α,β-不饱和酮的氢化硅烷化以及噻吩和吲哚的c-H键官能化反应中的应用实现了定量生产具有很高的可重用性.钯的催化活性达到数百mol Ppb,Ton达到2000000.
DOI:10.1002/anie.201308541

专利信息

专利号:US-2003050305-A1
优先权日:2000-05-22
标题:Thromboxane inhibitors, compositions and methods of use
发明人：TEJADA INIGO SAENZ DE
摘要:The present invention describes methods for treating or preventing sexual dysfunctions in males and females, and for enhancing sexual responses in males and females by administering a therapeutically effective amount of at least one thromboxane inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and/or at least one vasoactive agent. The male or female may preferably be diabetic. The present invention also provides novel compositions comprising at least one thromboxane inhibitor, and, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and, optionally, at least one therapeutic agent, such as, vasoactive agents, nonsteroidal antiinflanmmatory compounds (NSAIDs), selective cyclooxygenase-2 (COX-2) inhibitors, anticoagulants, angiotensin converting enzymes (ACE) inhibitors, angiotensin II receptor antagonists, renin inhibitors, and mixtures thereof. The present invention also provides methods for treating or preventing ischemic heart disorders, myocardial infarction, angina pectoris, stroke, migraine, cerebral hemorrhage, cardiac fatalities, transient ischaemic attacks, complications following organ transplants, coronary artery bypasses, angioplasty, endarterectomy, atherosclerosis, pulmonary embolism, bronchial asthma, bronchitis, pneumonia, circulatory shock of various organs, nephritis, graft rejection, cancerous metastases, pregnancy-induced hypertension, preeclampsia, eclampsia, thrombotic and thromboembolic disorders, intrauterine growth, gastrointestinal disorders, renal diseases and disorders, disorders resulting from elevated uric acid levels and dysmenorrhea, and for inhibiting platelet aggregation or platelet adhesion or relaxing smooth muscles.

专利号:US-4777257-A
优先权日:1983-08-25
标题:Certain tetrahydronaphthyl or indanylcarboxylates and derivatives thereof which inhibit the synthesis of thromboxane
发明人：KANAO MUNEFUMI
权利人:DAIICHI SEIYAKU CO
摘要:Benzocycloalkane derivatives of the formula (I) ##STR1## wherein: Z represents a methylene group or an ethylene group, either one of R 1 and R 2 represents --(CH 2 ) m --COOR 3 and the other represents ##STR2## wherein R 3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an interger of 1 to 6 and m represents an interger of 0 to 5, and the physiologically acceptable salts thereof; having a strong and selective inhibition activity of thromboxane A 2 synthesis.

专利号:JP-2004500344-A
优先权日:1999-10-29
标 题 :Synthesis of endogenous nitric oxide under low oxygen partial pressure

专利号:RU-2512491-C2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and use

专利号:BR-PI0719532-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelating agents for nuclear imaging and radiotherapy: compositions and applications

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.