CAS: 1125-21-9; 2,6,6-Trimethyl-2-Cyclohexene-1,4-Dione

相似化合物

78-59-1 14203-59-9 1125-21-9

上下游产品

CAS号471-01-2 3,5,5-三甲基-3-环己烯-1-酮 | CAS号78-59-1 异佛尔酮 | CAS号518316-69-3 (S)-4-hydroxy-3... | CAS号127-41-3 紫罗兰酮 | CAS号14203-59-9 4-hydroxyisophorone | CAS号23526-45-6 吐叶醇 | CAS号2408-37-9 2,2,6-三甲基环庚烷 | CAS号14203-64-6 7,9,9-trimethyl... | CAS号20547-99-3 2,2,6-三甲基-1,4-环己二酮 | CAS号13487-30-4 2,6,6-TRIMETHYL... | CAS号7479-28-9 1,4-Benzenediol...

异佛尔酮置于n-羟基邻苯二甲酰亚胺,氧气,Zinc(II) Chloride体系中,用 乙腈 用作溶剂,75.0 °C,1.2 Mpa 条件下,反应 5.0H,反应生成2,6,6-三甲基-2-环己烯-1,4-二酮
参考文献:An Efficient And Mild Oxidation Of α-Isophorone To Ketoisophorone Catalyzed By N-Hydroxyphthalimide And Copper Chloride
标题:An Efficient And Mild Oxidation Of α-Isophorone To Ketoisophorone Catalyzed By N-Hydroxyphthalimide And Copper Chloride
摘要:N-羟基邻苯二甲酰亚胺(nhpi)和氯化铜(cucl₂)首次被用于α-异佛尔酮(α-Ip)的有氧氧化,生成酮异佛尔酮(kip),并广泛研究了助催化剂,温度,反应时间,溶剂,Cucl₂ 的用量以及氧气压力的影响.Nhpi/cucl₂ 证明对该氧化反应具有高效性,在温和条件下达到最高 91.3% 的转化率和 81.0% 的选择性.此外,包括苯甲基化合物,环烯烃及其衍生物在内的各种烃在优化条件下也被顺利氧化.此外,还提出了可能的反应机制,并通过傅里叶变换红外光谱(ft-Ir)进行了验证.
Doi:10.5012/bkcs.2012.33.2.459

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-2005027142-A1
优先权日:2003-08-01
标题 :Method for synthesis of 2,2,6-trimethylcyclohexan-1-one
发明人：KLEINFELD SUSANNE; FISCHER ACHIM; WILZ FRANK; WECKBECKER CHRISTOPH; HUTHMACHER KLAUS
权利人:DEGUSSA
摘要:The present invention relates to a method for synthesis of 2,2,6-trimethylcyclohexan-1-one (TMCH) by partial reduction of 2,6,6-trimethyl-2-cyclohexen-1,4-dione (ketoisophorone, KIP), the reaction being carried out in the gas phase in the presence of oxide catalysts.

专利号:WO-2024133119-A1
优先权日:2022-12-19
标 题:Process for the synthesis of isophorone in the liquid phase, including recycling of the by-products
发明人：RUPPIN CHRISTOPHE
权利人:ARKEMA FRANCE
摘要:The present invention relates to a continuous process for the synthesis of isophorone in the liquid phase by alkaline self-condensation of acetone, comprising the following successive steps: a) continuously injecting, through a tubular reactor (R), a stream of an aqueous alkali hydroxide solution and a stream of an organic solution comprising acetone and by-products recycled in step g), followed by b) condensation reaction of the acetone in the tubular reactor (R), then c) distillation of the reaction mixture from the tubular reactor (R), then d) separation of the concentrated raw reaction product from the distillation of step c), resulting in an alkaline aqueous phase and an organic phase containing isophorone, then e) distillation of the organic phase containing the isophorone recovered in the preceding step, then f) distillation of the polycondensation sub-products from the bottom of the column (D2) from the preceding distillation, then g) recycling, to the tubular reactor (R), of the stream from the column head of the preceding distillation (D3), said stream comprising xylitones and/or isoxylitones.

专利号:US-5874632-A
优先权日:1996-05-15
标 题 :Method of producing ketoisophorone
发明人：HAHN RAINER; GORA ULRICH; HUTHMACHER KLAUS; HUEBNER FRANK; KRILL STEFFEN
权利人:DEGUSSA
摘要:An improved method of producing 3,5,5-trimethylcyclohex-2-ene-1,4-dione (KIP) by the oxidation of 3,5,5-trimethylcyclohex-3-ene-1-one ( beta -IP) in the presence of managansalene-like catalysts and certain catalytic additives. Byproducts:uct in the synthesis of trimethylhydroquinone, an initial substance in the synthesis of vitamin E. Furthermore, KIP is an initial compound for the synthesis of various carotinoids.

专利号:US-6103924-A
优先权日:1998-04-21
标 题 :Process for the preparation of 2,3,5-trimethylhydroquinone diesters
发明人：SHI NONGYUAN; SCHOLZ MARIO; HASENZAHL STEFFEN; WEIGEL HORST; DRAPAL BERND; MCINTOSH RALPH; HASSELBACH HANS J; HUTHMACHER KLAUS
权利人:DEGUSSA
摘要:Preparation of 2,3,5-trimethylhydroquinone diesters by rearrangement of 2,6,6-trimethylcyclohex-2-ene-1,4-dione (4-oxo-isophorone, ketoisophorone) in the presence of a solid, acid catalyst and an acylating agent, for example carboxylic acid anhydrides or carboxylic acid halides. The 2,3,5-trimethylhydroquinone diester may then optionally be saponified to the free 2,3,5-trimethylhydroquinone, which is a valuable building block in the synthesis of vitamin E.

专利号:WO-2020109533-A1
优先权日:2018-11-30
标 题:Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases
发明人：ARANDA OLIDEN Mª DEL CARMEN; DEL RÃ?O ANDRADE JOSÉ CARLOS; MARTÃ?NEZ FERRER Ã?NGEL TOMÃ?S; GUTIÉRREZ SUAREZ ANA
权利人:CONSEJO SUPERIOR INVESTIGACION
摘要:The process of the present invention relates to the biocatalytic transformation of isophorone (3,5,5-trimethylcyclohex-2-en-1-one) and 4-hydroxyisophorone by several unspecific peroxygenases produced by fungi. These biocatalysts, that only require H 2 O 2 or organic peroxides for activation, potentially represent a novel simple and environmentally friendly route for the production of isophorone derivatives, such as the high value products for the pharmaceutical and flavour and fragrance industry 4-hydroxyisophorone and 4-ketoisophorone.