CAS: 1993-03-9; (2-Fluorophenyl)Boronic Acid

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CAS号1072-85-1 1-溴-2-氟苯 | CAS号109-72-8 正丁基锂 | CAS号5419-55-6 硼酸三异丙酯 | CAS号462-06-6 氟苯 | CAS号348-52-7 邻氟碘苯 | CAS号367-12-4 2-氟苯酚 | CAS号348-51-6 2-氯氟苯 | CAS号342-24-5 2-氟二苯甲酮 | CAS号346656-39-1 2-(2-氟苯基)-5,5-二... | CAS号321-60-8 2-氟联苯 | CAS号380566-25-6 5-(2-氟苯基)呋喃-2-甲醛 | CAS号3794-15-8 1-苄基-2-1-苄基-2-氟苯氟苯 | CAS号388-82-9 2,2′-二氟联苯 | CAS号365-12-8 2'-氟-[1,1'-联苯]-4-羧酸 | CAS号23985-95-7 6H-benzo[h][1,6...

2-氟碘苯置于magnesium,硼酸三甲酯,盐酸体系中,用 乙醚 用作溶剂,化学反应生成2-氟苯硼酸
参考文献:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
标题:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
摘要:A Convenient Preparation Of K[arbf3] (Ar= 2-C6H4F,3-C6H4F,4-C6H4F,2,6-C6H3F2,3,5-C6H3F2,2,4,6-C6H2F3,3,4,5-C6H2F3,2,3,4,5-C6Hf4 And C6F5) Is Offered And The Ir And Multinuclear NMR Spectra Of These Salts Are Reported. Treatment Of The Trifluoroborate Salts With Bf3 In Chlorocarbon Solvents Provides An Easy Synthetic Route To The Corresponding Aryldifluoroboranes Arbf2. The Multinuclear NMR Spectra Of Arbf2 Are Presented. The Electron Substituent Effect Of The [-Bf3](-)-Group Shows This Substituent As One Of The Strongest Sigma-Electron Donors,While Its Pi-Electron Influence Is Negligible (Sigma(I) =-0.32,Sigma(R) =-0.07). (C) 2000 Elsevier Science S.A. All Rights Reserved.
Doi:10.1016/s0022-328X(99)00690-7

专利信息

专利号:WO-2011106929-A1
优先权日:2010-03-02
标题:Inhibitors of hepatitis c virus ns5b polymerase
发明人：MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO
权利人:MERCK SHARP & DOHME; ANGELETTI P IST RICHERCHE BIO; MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO
摘要:Compounds of formula I that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infection and for inhibiting HCV viral replication and /or viral production in a cell-based system.

专利号:US-2012328569-A1
优先权日:2010-03-02
标题:Inhibitors of hepatitis c virus ns5b polymerase
发明人：MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
权利人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
摘要:Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-8207337-B2
优先权日:2007-01-29
标 题:Reagent for organic synthesis reaction containing organic triol borate salt
发明人：MIYAURA NORIO; YAMAMOTO YASUNORI
权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD
摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).

专利号:US-2024215280-A1
优先权日:2022-10-31
标 题:In situ core/shell perovskite nanocrystal material, method of preparation thereof, and light emitting device comprising the same
发明人：LEE TAE-WOO; KIM JOO SUNG
权利人:SEOUL NAT UNIV R&DB FOUNDATION; PEROLED CO LTD
摘要:The present inventive concept relates to an in situ core/shell perovskite nanocrystal film formed by an in situ nanocrystal synthesis process, a method for producing the same, and a light emitting device comprising the same as a light-emitting layer. The in situ core/shell perovskite nanocrystal film formed by the in situ nanocrystal synthesis process according to the present inventive concept exhibits a strong charge confinement effect by nanocrystal formation, and can simultaneously greatly improve the luminescence efficiency and lifetime by maintaining the fast charge transport capability of polycrystalline perovskite.

专利号:US-2010022541-A1
优先权日:2006-09-25
标题:Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors
发明人：ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
权利人:ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
摘要:The invention relates to new compounds having heptose synthesis inhibitory properties, of formula (I) or a pharmaceutically acceptable salt, or prodrug thereof, wherein A is an aryl or heterocycle, optionally substituted by one or several identical or different R such as H, C1-C10 alkyl, C1-C10 alkyl-OR 1 , C1-C10 alkyl-NR 1 R 1 , alkoxy, hydroxy, thioalkyl, aryl, heterocycle, halogen, nitro, cyano, CO 2 R 1 , NR 1 R 1 , NR 1 C(O)R 1 , C(O)NR 1 R 1 , NR 1 C(S)R 1 , C(S)NR 1 R 1 , SO 2 NR 1 R 1 , SO 2 R 1 , NR 1 SO 2 R 1 , NR 1 C(O)NR 1 R 1 , NR 1 C(O)OR 1 , NR 1 C(S)NR 1 R 1 , NR 1 C(S)OR 1 , R 1 Câ• NOR 1 , C(O)R 1 , aryloxy, thioaryl, alkenyl, alkynyl R1 identical or different is H or C1-C10 alkyl B 1 , B 2 , B 3 identical or not represent C, N, O, S to form a five-membered aromatic ring wherein from one to three carbon atoms are replaced by a heteroatom selected from S, O, N optionally substituted by one or several identical or different R such as defined above B 4 is C or N Y is H, C1-C10 alkyl, alkoxy, thio-alkyl, optionally substituted by one or several identical or different R such as defined above W is C, O or N, substituted or not by one or several C1-C10 alkyl radicals D is an heterocycle optionally substituted by one or several identical or different R such as defined aboe.

专利号:EP-2046804-A1
优先权日:2006-06-30
标题 :Synthesis of diethyl{ i5' (3 -fluorophenyl) -pyridine-2-yl] methyl} phosphonate used in the synthesis of himbacine analogs