CAS: 20859-02-3; (S)-2-Amino-3,3-Dimethylbutanoic Acid

相似化合物

26782-71-8 33105-81-6 132684-60-7

上下游产品

CAS号62965-35-9 N-B°C-L-叔亮氨酸 | CAS号111525-71-4 (S)-2-叠氮-3,3-二甲基丁酸 | CAS号62965-57-5 Butanamide, 2-a... | CAS号162377-68-6 (2S)-2-benzamid... | CAS号139163-43-2 (S)-2-氨基-3,3-二甲... | CAS号36965-30-7 1,1,1-trichloro... | CAS号139040-45-2 (R)-1,1,1-trich... | CAS号319930-78-4 (R)-2-amino-3,3... | CAS号1067225-04-0 N-[[[2-(二苯基膦基)苯... | CAS号394730-60-0 波普瑞韦 | CAS号572924-00-6 N-环戊氧羰基-L-叔亮氨酸 | CAS号144054-70-6 (S)-(-)-2-氨基-3,... | CAS号630-19-3 三甲基乙醛 | CAS号89226-12-0 L-叔亮氨酸甲基酰胺 | CAS号65050-07-9 (S)-3-叔丁基-2,5-哌嗪二酮 | CAS号62965-56-4 (S)-(-)-4-叔丁基氧氮... | CAS号62965-10-0 Cbz-L-叔亮氨酸 | CAS号62965-35-9 N-B°C-L-叔亮氨酸

Dl-叔亮氨酸置于l-2-氨基丁酸,ω-Transaminase,Branched-Chain Transaminase From Escherichiacoli,S-Selective ω-Transaminase From ochrobactrum Anthropi,丁-1,3-二烯1,2-二乙烯基苯苯乙烯,异丙胺体系中,用 Aq. Phosphate Buffer 用作溶剂,化学反应 18.0H,反应生成L-叔亮氨酸
参考文献:通过伯胺的氨基级联转移到酮酸上的非天然氨基酸的生物催化不对称合成.
标题:通过伯胺的氨基级联转移到酮酸上的非天然氨基酸的生物催化不对称合成.
摘要:逃往山上:通过α-转氨酶反应作为平衡转移剂,成功克服了α-转氨酶催化的氨基酸和酮酸之间的氨基转移平衡失衡,从而有效地不对称合成了多种非天然氨基酸包括大号-叔-亮氨酸和d-苯基甘氨酸.
Doi:10.1002/cctc.201300571

专利信息

专利号:WO-8800592-A1
优先权日:1986-07-18
标题:DIASTEROSELECTIVE STRECKER SYNTHESIS OF alpha-AMINOACIDS FROM GLYCOSYLAMINE DERIVATES
发明人：KUNZ HORST; SAGER WILFRIED; PFRENGE WALDEMAR; DECKER MATHIAS
权利人:CELAMERCK GMBH & CO KG
摘要:O-acyl-protected glycosylamines, in particular 2,3,4,6-tetra-O-pivaloyl-beta-D-galactopyranosylamine (1), their preparation and their use for the diastereoselective synthesis of alpha-aminoacids. With compounds such as (1), one can obtain by Strecker synthesis high yields and high diastereomer surplus. The direction of the asymmetric induction can be determined by the selection of the solvent. This type of synthesis is particularly effective when carried with Lewis acid catalysts. One obtains also high yields and high diastereoselectivity during Ugi four component synthesis facilitated by Lewis acids by using amines such as (1).

专利号:US-2023313255-A1
优先权日:2020-07-15
标题:Massively Parallel Enzymatic Synthesis of Polynucleotides
发明人：HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER
权利人:DNA SCRIPT
摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.

专利号:US-2023159450-A1
优先权日:2020-05-08
标 题 :Dimers for use in synthesis of peptidomimetics
发明人：AL-ABED YOUSEF; ALTITI AHMAD
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Dimers for use in synthesis of peptidomimetics are described. Uses of dimers as synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the dimers and uses of azapeptides and other peptidomimetics are also described.

专利号:WO-2014095657-A1
优先权日:2012-12-20
标题:Synthesis of a viral protease inhibitor intermediate
发明人：RIVA SERGIO; ALLEGRINI PIETRO; ATTOLINO EMANUELE; GRAZIOSI RENZO
权利人:DIPHARMA FRANCIS SRL
摘要:Synthesis of an intermediate useful in the synthesis of a viral protease inhibitor, and its use in the preparation of said inhibitor.

专利号:US-2023278959-A1
优先权日:2020-05-04
标题:Synthesis of Optically Active Indoline Derivatives Via Ruthenium(II)-Catalyzed Enantioselective C-H Functionalization
发明人：CUI XIN; LI ZHONG-YUAN; CHAMINDA LAKMAL HETTI HANDI
权利人:UNIV MISSISSIPPI STATE
摘要:Provided herein are a method of Ru(II)-catalyzed enantioselective synthesis of a cyclic compound and cyclic compounds formed therefrom. The method includes providing a precursor compound having an unfunctionalized C—H bond and activating the unfunctionalized C—H bond by reacting the precursor compound in the presence of co-catalysts including a Ru(II) arene complex and a chiral transient directing group (CTDG).

专利号:US-9938509-B2
优先权日:2010-12-08
标 题 :Biocatalysts and methods for the synthesis of armodafinil
发明人：ANG EE LUI; ALVIZO OSCAR; BEHROUZIAN BEHNAZ; CLAY MICHAEL D; COLLIER STEVEN J; EBERHARD ELLEN D; FAN FU; SONG SHIWEI; SMITH DEREK J; WIDEGREN MAGNUS; WILSON ROBERT; XU JUNYE; ZHU JUN
权利人:CODEXIS INC
摘要:The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (−)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.