CAS: 814-75-5; 3-Bromobutan-2-One

相似化合物

2648-71-7 19967-55-6 5798-80-1

上下游产品

2-acetoxy-2-butene butanone acetic acid 2,3-dimethyl-2-nitro-oxirane 3-(1'-pyrrolidinyl)-2-butanone 3-cyclohexylidene-butan-2-one 3-((4-methoxyphenyl)amino)butan-2-one 4,5-Dimethylthiazole

丁酮置于hexabromocyclopenta-1,3-Diene体系中,用 乙腈 作为反应溶剂,化学反应 17.5H,以82%的收率获得产物3-溴-2-丁酮
参考文献:新型溴化剂.六溴环戊二烯:活化饱和位点的溴化
标题:新型溴化剂.六溴环戊二烯:活化饱和位点的溴化
摘要:六溴环戊二烯(hbc)容易溴化α-酮和苄基位点,显然是通过溴离子转移.
DOI:10.1016/s0040-4039(01)81387-3

专利信息

专利号:US-2010222601-A1
优先权日:2006-12-12
标题 :Synthesis of cyclopentadiene derivatives
发明人：TAHIRI OUARDIA; JONES ROBERT L; SCHIENDORFER MICHAEL; CHEVALIER REYNALD
权利人:BASELL POLYOLEFINE GMBH
摘要:A process for preparing cyclopentadiene derivatives having formula (I) n n n n n n n n n n Wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 equal to or different from each other, are hydrogen atoms or hydrocarbon groups comprising the steps of reacting a substituted or unsubstituted indanon with a base and then with a substituted or unsubstituted haloaceton and treating the obtained product with the Lawesson's reagent.

专利号:US-10807941-B2
优先权日:2016-06-03
标题:Process for the preparation of polysantol-type compounds
发明人：KNOPFF OLIVER
权利人:FIRMENICH & CIE
摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a novel compound of formula (I). The invention additionally relates to a process for preparing a compound of formula (III) using the compound of formula (I) as an intermediate, wherein the process involves elimination of the R3(X)nC(â•?O)O functional group of the compound of formula (I).

专利号:US-6586453-B2
优先权日:2000-04-03
标 题:Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
发明人：DHANOA DALE S; RYAN DECLAN E; DECKMAN INGRID; SAPIENZA ANTHONY
权利人:DIMENSIONAL PHARM INC
摘要:The present invention relates to the use of aminothiazole derivatives of Formula I of as inhibitors of PAI-1, and to novel classes of aminothiazole derivatives, their synthesis and their use as inhibitors of PAI-1. It has been discovered that compounds of Formula I:or a solvate, hydrate or a pharmaceutically acceptable salt thereof, whereinY, Ar1, Ar2, R1, R2, Z, m and n are described in the specification, inhibit plasminogen activator inhibitor-1 (PAI-1). These compounds can be used in the prophylaxis or for the treatment of thrombosis, angina pectoris, cerebral infarction, myocardial infarction, pulmonary infarction, intra-atrial thrombus in atrial fibrillation, deep venous thrombus, disseminated intravascular coagulation syndrome, diabetic complications, restenosis and stroke.

专利号:US-4246173-A
优先权日:1978-04-24
标题 :Process for preparing tetraselenofulvalenes, and conductive salts obtained therefrom
发明人：COWAN DWAINE O; BLOCH AARON N; BECHGAARD KLAUS
权利人:UNIV JOHNS HOPKINS
摘要:A multistep process for preparing tetraselenofulvalenes involving the synthesis of 1,3-diselenole-2-selones and -2-thiones from diselenocarbamates and α-haloketones followed by coupling of the selone or thione using a dechalkogenizing reagent. New highly conductive salts obtained by coupling certain tetraselenofulvalenes with acceptor compounds are also disclosed.

专利号:US-8987195-B2
优先权日:2012-08-08
标 题:HCV NS3 protease inhibitors
发明人：BARA THOMAS; BHAT SATHESH; BISWAS DIPSHIKHA; BROCKUNIER LINDA; BURNETT DUANE A; CHACKALAMANNIL SAMUEL; CHELLIAH MARIAPPAN V; CHEN AUSTIN; CLASBY MARTIN; COLANDREA VINCE J; GUO ZHUYAN; HAN YONGXIN; JAYNE CHARLES; JOSIEN HUBERT; MARCANTONIO KAREN; MIAO SHOUWU; NEELAMKAVIL SANTHOSH; PINTO PATRICK; RAJAGOPALAN MURALI; SHAH UNMESH; VELAZQUEZ FRANCISCO; VENKATRAMAN SRIKANTH; XIA YAN
权利人:MERCK SHARP & DOHME; MERCK CANADA INC
摘要:The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.

专利号:US-7772246-B2
优先权日:2007-08-01
标题:Pyrazole compounds as RAF inhibitors
发明人：CUI JINGRONG JEAN; DEAL JUDITH GAIL; GU DANLIN; GUO CHUANGXING; JOHNSON MARY CATHERINE; KANIA ROBERT STEVEN; KEPHART SUSAN ELIZABETH; LINTON MARIA ANGELICA; MCALPINE INDRAWAN JAMES; PAIRISH MASON ALAN; PALMER CYNTHIA LOUISE
权利人:PFIZER
摘要:The present invention is directed to compounds of Formula (I), n nand to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.