专利号:US-7956169-B1 优先权日:2010-06-16 标题 :Synthesis of novel azo-dyes and their use in oligonucleotide synthesis 发明人:LAIKHTER ANDREI; SRIVASTAVA SURESH C; SRIVASTAVA NAVEEN P 权利人:CHEMGENES CORP 摘要:The invention provides a novel group of azo quencher compositions that are useful as quenchers of fluorescence and to methods for making and using them. The quenchers contain an azo bond and 1,3,3-trimethyl-2-methyleneindoline ring system. The quenchers can be derivatized to facilitate their conjugation to a variety of biologically relevant compounds, including lipids, nucleic acids, peptides, proteins, and the like.
专利号:US-2023295613-A1 优先权日:2020-02-14 标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming 发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:US-11814621-B2 优先权日:2018-06-01 标题 :Expanding the chemical substrates for genetic code reprogramming 发明人:JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:EP-2397464-A1 优先权日:2010-06-16 标题:Synthesis of novel azo-dyes and their use in oligonucleotide synthesis
专利号:EP-2397464-B1 优先权日:2010-06-16 标 题 :Synthesis of novel azo-dyes and their use in oligonucleotide synthesis
专利号:US-4828622-A 优先权日:1984-11-06 标题:Process for preparing highly concentrated aqueous press cakes of solids 发明人:WEIDE JOACHIM; DIETZ ERWIN; DEUBEL REINHOLD 权利人:HOECHST AG 摘要:According to the invention, addition of one or more surfactants having a cloud point in aqueous solution to an aqueous suspension of a solid gives after the isolation of the solid at a temperature above the cloud point aqueous press cakes containing a large amount of this solid. The direct processing of press cakes as obtained for example after the synthesis and isolation of dyes or pigments to give practical aqueous pastes or dispersions requires a minimum solids content in the press cakes. The minimum content is frequently not obtained when conventional methods of isolation are used, so that it is necessary to proceed via the indirect route of drying to obtain the powders and redispersing the powders. By using the process according to the invention it is possible to cut out the costly indirect route or, if desired, to reduce the expense of drying to obtain powders by an appreciable margin.
参考标题:Synthesis Of Indoles: Efficient Functionalisation Of The 7-Position 作者:Emmanuel Demont,Nicolas Charrier,Rachel Dunsdon,Graham Maile,Alan Naylor,Alistair O'Brien,Sally Redshaw,Pam Theobald,David Vesey,Daryl Walter |发布日期:2006.10 摘要:Traditional Strategies In Indole Chemistry Do Not Allow High-Yielding Access To Some Substitution Patterns Such As 3,5,7-Trisubstituted Indoles. We Report In This Article The Efficient Synthesis Of This Type Of Indole. The Heck Cyclisation Strategy We Used Allows The Synthesis Of 7-Iodo-, 7-Alkoxy-, 7-Amino-, And 7-Nitroindoles Bearing Other Functionalities At The 3- And 5-Positions. We Believe That
合成参考文献
参考文献:10.1107/s1600536810040146 摘要:Win YF, Choong CS, Teoh SG, Goh JH, Fun HK. Bis(μ(2)-4-amino-3-nitro-benzoato)bis-(4-amino-3-nitro-benzoato)octa-butyldi-μ(3)-oxido-tetra-tin(IV). Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 13;66(Pt 11):m1406–7.