专利号:US-2013165350-A1 优先权日:2011-12-22 标 题:Surface linkers for array synthesis 发明人:KUIMELIS ROBERT; MCGALL GLENN; PAO DEXTER; CHEN ZIHUI; AXELROD TREVOR 权利人:KUIMELIS ROBERT; MCGALL GLENN; PAO DEXTER; CHEN ZIHUI; AXELROD TREVOR; AFFYMETRIX INC 摘要:The present invention provide several methods of derivatizing a surface of a support with one or more linkers thus providing a suitable platform for synthesis of a polymer array, particular a nucleic acid array. Some methods derivatize a surface with a self-assembled monolayer (SAM) of a linker. The SAM confers advantages of hydrolytic stability, broad compatibility with synthesis and detection chemistries, and reduced emergence of latent functional groups during polymer array synthesis. Substrates can also be derivatized with multi-layers of SAMs providing greater hydrolytic stability. Substrates can also be derivatized by synthesizing a linker in situ on the substrate by atom transfer radical polymerization of functional and functional monomers. Appropriate selection of monomers reduces emergence of latent functional groups in subsequent array synthesis.
专利号:CN-107216242-A 优先权日:2017-07-07 标题 :A method for the synthesis of aromatic aldehydes, aromatic ketones and aromatic esters by iron-catalyzed oxidation of alkyl aromatic compounds
专利号:US-2626268-A 优先权日:1948-12-11 标 题 :Synthesis of aliphatic silanes 发明人:JOHN BARRY ARTHUR; DE PREE LEE; EUGENE HOOK DONALD 权利人:DOW CHEMICAL CO
专利号:CN-110256327-A 优先权日:2019-06-20 标题:A kind of method that iron catalyzes the synthesis of 2-indolinone compound of oxidized indole compound
专利号:CN-100402475-C 优先权日:2006-05-16 标题:Method for direct chlorination synthesis of chlorohydrocarbon adopting chlorosilane carbonyl compound
专利号:US-5808162-A 优先权日:1995-07-21 标题:Chiral unsymmetric diphosphine compound and transition metal complex containing the same as ligand 发明人:SAYO NOBORU; ZHANG XIAOYONG; OMOTO TATSUYA; YOKOZAWA TOHRU; YAMASAKI TETSURO; KUMOBAYASHI HIDENORI 权利人:TAKASAGO PERFUMERY CO LTD 摘要:A novel chiral unsymmetric diphosphine compound of formula (I): ##STR1## wherein Ar 1 and Ar 2 , which are different from each other, each represent a substituted or unsubstituted phenyl group, a substituted or unsubstituted naphthyl group, a pyridyl group, a quinolyl group, an isoquinolyl group, a furfuryl group, a benzofurfuryl group, a thienyl group, or a benzothienyl group, and a transition metal complex containing the diphosphine compound as a ligand. The complex catalyzes various asymmetric synthesis reactions, e.g., asymmetric hydrogenation or asymmetric hydrosilylation, exhibiting excellent performance in selectivity, conversion and catalytic activity, to provide a product of desired absolute configuration at high optical purity and in high yield.