CAS: 16839-97-7; 2-Methoxythiophene

该化合物是一种有机化合物,其特点是五人组成的芳香环,含有硫磺和氧原子.具体地说,它有一个硫苯环,配有与第二个碳原子相连的甲氧基组(OCH),这种替代会影响其化学特性,使其更极化,提高有机溶剂中的溶解性.甲基氧组的存在还可能影响硫苯的电子特性,有可能增加其在电子替代反应中的再活动.2-甲基苯基通常无色,可粉色的黄色液体有独特的味.它用于各种应用,包括有机合成,作为更复杂的分子的建筑块,以及由于其导力特性而在开发电子材料时使用.此外,它可能表现出有趣的光物理特性,从而有可能用于有机发光二极(OLEDs)和其他多光电子装置.在处理这一化合物时,应当采取安全防范措施,因为许多有机化学品具有潜在的毒性和环境影响.

结构式图片

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35087-46-8 58386-20-2 33687-87-5

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上下游产品

CAS号1003-09-4 2-溴噻吩 | CAS号124-41-4 甲醇钠 | CAS号3437-95-4 2-碘噻吩 | CAS号67-56-1 甲醇 | CAS号3354-32-3 2(5H)-噻吩 | CAS号3140-93-0 2,3-二溴噻吩 | CAS号77998-60-8 (5-methoxythiop... | CAS号19259-06-4 2,4-diiodothiophene | CAS号163928-54-9 5-methoxy-2,2’-... | CAS号492-97-7 2,2'-双噻吩 | CAS号29212-22-4 5-甲氧基-2-噻吩甲酸 | CAS号95-15-8 苯并噻吩 | CAS号5632-29-1 α-四联噻吩 | CAS号138706-52-2 2-methoxy-5-(5-... | CAS号33333-57-2 3-thiophen-2-yl... | CAS号35087-46-8 5-甲氧基噻吩-2-甲醛

合成工艺路线路线简述

    2-溴噻吩置于sodium Methylate,Sodium,Copper(I) Bromide体系中,用 甲醇,水 用作溶剂,以76%的收率获得2-甲氧基噻吩
    参考文献:Us6184242
    标题:Us6184242

    海关参考信息

    专利信息


    专利号:EP-1108724-B1
    优先权日:1996-01-16
    标题 :Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
    发明人:WINCOTT FRANCINE; BEIGELMANN LEONID; MATULIC-ADAMIC JASENKA; USMAN NASSIM; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID; JARVIS THALE; DIRENZO ANTHONY
    权利人:SIRNA THERAPEUTICS INC
    摘要:This invention relates to chemical synthesis of 2'-O-methyl, 3'-O-methyl and 5'-O-methyl nucleosides, incorporation of novel chemical modifications in enzymatic nucleic acid molecules and improved methods for the synthesis of enzymatic nucleic acid molecules.

    专利号:US-6972330-B2
    优先权日:1996-02-13
    标题:Chemical synthesis of methoxy nucleosides
    发明人:BEIGELMAN LEONID; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID
    权利人:SIRNA THERAPEUTICS INC
    摘要:Process for chemical synthesis of methoxy nucleosides.

    专利号:US-6413957-B1
    优先权日:1998-04-21
    标题:Methods of inhibiting cell proliferation using indeno [1,2-c]pyrazol-4-ones
    发明人:NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
    权利人:BRISTOL MYERS SUIBB PHARMA COM
    摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

    专利号:US-8642798-B2
    优先权日:2004-12-07
    标 题:Silacycle compounds and methods of use thereof
    发明人:LEIGHTON JAMES LINCOLN; BERGER RICHARD; SHIRAKAWA SEIJI; NOTTE GREGORY T
    权利人:LEIGHTON JAMES LINCOLN; BERGER RICHARD; SHIRAKAWA SEIJI; NOTTE GREGORY T; TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    摘要:The present invention relates to a diastereomeric mixture of Silacycle Compounds and methods for using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis.

    专利号:US-9395371-B2
    优先权日:2010-09-24
    标题:Synthesis of fluorescent noble metal nanoparticles
    发明人:CHAN WARREN; PERRAULT STEVEN; CHOU LEO
    权利人:CHAN WARREN; PERRAULT STEVEN; CHOU LEO
    摘要:A process for the production of fluorescent nanoparticles selected from noble metal or silica nanoparticles. Noble metals or silica nanoparticles provide a platform to which fluorophores and other detection molecules can be added. The fluorescent nanoparticles can be used as regents, diagnostic assays and in the tracking or targeting of tumors.

    专利号:US-3983120-A
    优先权日:1974-11-06
    标 题 :Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
    发明人:BEVERUNG WARREN NEIL; PARTYKA RICHARD ANTHONY
    权利人:BRISTOL MYERS CO
    摘要:A new process has been developed for the synthesis of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Heterogeneously Catalyzed Direct Ch Thiolation Of Heteroarenes
    作者:Suhelen Vásquez-Céspedes,Angélique Ferry,Lisa Candish,Frank Glorius |发布日期:2015.5.4
    摘要:The First General Methodology For The Direct Thiolation Of Electron‐rich Heteroarenes Was Developed By Employing Pd/al2O3, A Recoverable And Commercially Available Heterogeneous Catalyst, And Cucl2. This Method Represents An Operationally Simple Approach For The Synthesis Of These Valuable Compounds. Preliminary Mechanistic Studies Indicate A Heterogeneous Catalytic System, In Which Both Metals Play

    合成参考文献


    摘要:Schatz, J.; Seler, M., Science of Synthesis Knowledge Updates, (2011) 2, 409.
    摘要:Schatz, J.; Seler, M., Science of Synthesis Knowledge Updates, (2011) 2, 382.
    摘要:Schatz, J.; Seler, M., Science of Synthesis Knowledge Updates, (2011) 2, 381.
    摘要:Schatz, J.; Seler, M., Science of Synthesis Knowledge Updates, (2011) 2, 396.
    摘要:Ipaktschi, J.; Saidi, M. R., Science of Synthesis Knowledge Updates, (2012) 4, 410.
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