CAS: 5922-60-1; 2-Amino-5-Chlorobenzonitrile

相似化合物

20028-53-9 5202-85-7 635-21-2

上下游产品

5-Chloroisatin 3-oxime 3-chloro-6-nitrobenzonitrile 4-chloro-aniline trichloroacetonitrile 2-Amino-5-chlor-2'-methyl-diphenylketoimin 2-Cyano-4-selen°Cyanatoaniline (2-amino-5-chlorophenyl)-phenyl-methane-imine 5-chloro-2-(methylamino)benzonitrile

2-氨基苯甲腈置于n-氯代丁二酰亚胺,二氟溴乙酸,2,4,5,6-四(9H-咔唑-9-基)异酞腈体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.5H,以89%的收率获得产物2-氨基-5-氯苯腈
参考文献:通过光/有机共催化(杂)苯胺的 C-H 氯化
标题:通过光/有机共催化(杂)苯胺的 C-H 氯化
摘要:氯化(杂)苯胺是一类重要的结构基序,广泛存在于合成结构单元和药物中.尽管最近取得了进展,但直接苯胺氯化仍然存在邻/对和单/多氯化选择性问题.在此,我们公开了一种用于苯胺的光氧化还原和有机共催化氯化方法.该方法具有很好的底物通用性和优异的单氯化选择性.这种方法的另一个优点是药物分子的后期修饰,这将在药物化学中有用.
DOI:10.1039/d2Ob00834C

专利信息

专利号:US-11718584-B2
优先权日:2019-02-22
标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof
发明人：KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR
权利人:PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)

专利号:US-4713383-A
优先权日:1984-10-01
标 题:Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
发明人：FRANCIS JOHN E; GELOTTE KARL O
权利人:CIBA GEIGY CORP
摘要:[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N-R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N-R3.

专利号:US-11365267-B2
优先权日:2019-06-04
标题 :Fluorine-containing alternating copolymer macromonomer and synthesis method thereof
发明人：CHENG ZHENPING; CHENG JIANNAN; WANG JINYING; TU KAI; ZHU XIULIN
权利人:UNIV SOOCHOW
摘要:The present invention relates to a fluorine-containing alternating copolymer macromonomer and a synthesis method thereof. The synthesis method comprises steps of: subjecting a fluorine-containing alternating copolymer to a reduction reaction at 60-100° C. in an organic solvent in the presence of a reducing agent and a first catalyst to obtain a reduction product; in the presence of a second catalyst, reacting the reduction product with a mercapto-monohydric alcohol in an organic solvent at 60-100° C., to obtain a hydroxyl-terminated fluorine-containing alternating copolymer; and in the presence of a third catalyst, reacting the hydroxyl-terminated fluorine-containing alternating copolymer with an acrylic monomer or acryloyl chloride monomer at 0-30° C., to obtain the fluorine-containing alternating copolymer macromonomer. In the present invention, a fluorine-containing alternating copolymer macromonomer is initially synthesized from a fluorine-containing alternating copolymer through polymer modification.

专利号:US-4740604-A
优先权日:1986-05-26
标题:Benzanthrone lactones
发明人：WEIS CLAUS D; SUTTER PETER
权利人:CIBA GEIGY CORP
摘要:There are disclosed benzanthrone lactones of formula ##STR1## wherein R 1 , R 2 and R 3 are as defined in claim 1. The benzanthrone lactones of formula (1) are important intermediates for the synthesis of novel dyes which are obtained by coupling suitable diazo components to said compounds of formula (1).

专利号:US-12351847-B2
优先权日:2019-10-16
标题 :Methods for the improved formation of acarbose
发明人：PUHLER ALFRED; KALINOWSKI JORN; SCHNEIKER-BEKEL SUSANNE; PERSICKE MARCUS; SCHAFFERT LENA
权利人:BAYER AG
摘要:The present invention relates to Actinomycetales strains for the improved formation of acarbose. Provided are Actinomycetales strains which are engineered to overexpress dTDP-D-glucose-4,6-dehydratase (AcbB) and/or uridyltransferase (GtaB). Also provided are Actinomycetales strains which are engineered to have a reduced or absent expression of the small carbohydrate binding protein (Cgt) and/or a reduced or absent expression of genes which are essential for carotenoid synthesis. Also provided are tools, methods and means to generate these strains.

专利号:US-4338318-A
优先权日:1979-03-23
标 题 :Novel compositions and methods
发明人：HENRICK CLIVE A; LABOVITZ JEFFREY N; FOX ROLAND T V; RATHMELL WILLIAM G; SHEPHARD MARGARET C
权利人:ZOECON CORP
摘要:Novel 1-substituted uracils, synthesis and intermediates therefor, and compositions for the control of pests.