CAS: 1212-53-9; Z-Gly-Ome

该化合物是属于氨基酸衍生物类别的有机化合物,其特征是甲基酯功能组,它有助于有机溶剂中的溶性.苯氧碳氢化合物组的存在提供了稳定性,保护氨基组,使其在peptide合成和其他有机反应中有用.该化合物一般是白色至非白色固体的化合物,其特点是其相对较低的熔点和中度沸点,表明其分子结构.甲基N-苯氧碳氢化合物在合成更复杂的分子中经常使用,特别是在制药和生物化学领域,因为其有能力作为peptide形成的一个建筑块.其活性可能受到功能组的存在的影响,允许各种化学变异.在处理和储存时,应参考安全数据,如同任何化学物质一样,以确保适当的实验室做法.

英文名称Z-Gly-Ome
中文名称N-苄氧羰基甘氨酸甲酯
IUPAC名称methyl ((benzyloxy)carbonyl)glycinate
其它别名Methyl 2-{[(Benzyloxy)Carbonyl]Amino}Acetate; N-Benzyloxycarbonylglycine Methyl Ester; N-Benzyloxycarbonyl-Glycine Methyl Ester; Glycine, N-((Phenylmethoxy)Carbonyl)-, Methyl Ester; Methyl ([(Benzyloxy)Carbonyl]
CAS编号1212-53-9
MFCD编号:MFCD00043631
EINECS号:214-922-8
FDA UNII编号:FJN4H3C4H6
分子式:C11H13NO4
分子量:223.23
产品CID: 287792
产品分类有机原料→生命科学→氨基酸及其衍生物→甘氨酸及其衍生物

相似结构搜索
产品信息参考;
InChIKey: DZYBBBYFLOPVOL-UHFFFAOYSA-N
InChI=1S/C11H13NO4/c1-15-10(13)7-12-11(14)16-8-9-5-3-2-4-6-9/h2-6H,7-8H2,1H3,(H,12,14)…
计算化学: 氢键受体数4.0氢键供体数1.0可旋转键数4.0

相似化合物

3154-54-9 42492-57-9 2645-02-5

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志Xi

上下游产品

合成工艺路线路线简述

N-Carbobenzoxy-N-Chloroglycine Methyl Ester置于三乙胺体系中,用95%的收率获得cbz-甘氨酸甲酯
参考文献:Preparation Of Protected α-Alkoxyglycines
标题:Preparation Of Protected α-Alkoxyglycines
摘要:N-Carbobenzoxy-Alpha-Alkoxyglycine Esters Were Synthesized By H2So4-Catalyzed O-Alkylation Of N-Carbobenzoxy-Alpha-Hydroxyglycine And Also By Base Treatment Of N-Carbobenzoxy-N-Chloroglycine Methyl Ester In The Corresponding Alcohol. Saponification Of The Protected Alpha-Alkoxyglycines Gave Free Acids Which Can Be Used For The Synthesis Of Alpha-Alkoxyglycine Residue-Containing Peptides.
Doi:10.1080/00397919608003521

海关参考信息

2902300000-甲苯
2906210000-苄醇
2912110000-甲醛
2912120000-乙醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9403760-B2
优先权日:2013-03-14
标题 :Compounds
发明人：BURGESS STEPHEN W; SHAW WALTER A; LI SHENGRONG
权利人:AVANTI POLAR LIPIDS INC
摘要:Disclosed are compounds of the general formula I and II (as further defined herein) are useful in the production of inhibitors of sphingolipid synthesis the production of sphingolipids. Suitable sphingolipids, include, but not limited to, sphingosine and compounds incorporating sphingosine or that may use sphingosine as an intermediate or a starting material in their synthesis (including, but not limited to, sphingosine-1-P, ceramide, gangliosides and sphingomyelin). In one contemplated use, compounds of the general formula I and II are useful in the production of sphingosine. In another contemplated use, compounds of the general formula I and II are useful in the production of a sphingofugin. Methods of manufacturing each of the above compounds are also provided.

专利号:US-2016024001-A1
优先权日:2013-03-14
标题 :Novel compounds
发明人：BURGESS STEPHEN W; SHAW WALTER A; LI SHENGRONG
权利人:AVANTI POLAR LIPIDS INC
摘要:Disclosed are compounds of the general formula I and II (as further defined herein) are useful in the production of inhibitors of sphingolipid synthesis the production of sphingolipids. Suitable sphingolipids, include, but not limited to, sphingosine and compounds incorporating sphingosine or that may use sphingosine as an intermediate or a starting material in their synthesis (including, but not limited to, sphingosine-1-P, ceramide, gangliosides and sphigomyelin). In one contemplated use, compounds of the general formula I and II are useful in the production of sphingosine. In another contemplated use, compounds of the general formula I and II are useful in the production of a sphingofugin. Methods of manufacturing each of the above compounds are also provided.

专利号:CN-115160430-A
优先权日:2022-07-27
标题:Synthesis method of somaglutide backbone fragment

专利号:CN-113896701-A
优先权日:2021-10-20
标题 :A kind of synthesis process of Hsp90 inhibitor KU-177